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Carrington Subsidiary DelSite Biotechnologies Enters into Technology Evaluation Rights License Agreement for Transdermal Delivery of Vaccines
Date:9/19/2007

Application Would Expand Versatility of DelSite cGMP Polymer

IRVING, Texas, Sept. 19 /PRNewswire-FirstCall/ -- Carrington Laboratories, Inc. (Pink Sheets: CARN) today announced its wholly-owned subsidiary, DelSite Biotechnologies, Inc., entered into a technology evaluation rights license agreement with a biotechnology company for transdermal delivery of vaccines using GelSite(R) polymer, DelSite's high-molecular-weight anionic polysaccharide which is produced under cGMP with high purity at a kilogram scale. Financial terms of the agreement were not disclosed.

As part of the agreement, DelSite will provide GelSite(R) polymer and assistance in formulation development of a transdermal vaccine. Transdermal vaccination avoids needle sticks, pain or tissue damage and offers distinct advantages over conventional vaccination regimens. The objective of the program is to develop an effective vaccine formulation that may further enhance the immune response following through-the-skin delivery. The GelSite(R) polymer's distinct chemical and functional properties, including its capability for in-situ gel formation that provides a matrix for sustained antigen release, may make it an especially suitable platform for noninvasive transdermal vaccination delivery.

This agreement is a new addition to DelSite's delivery technology programs in the vaccine areas. So far this year, DelSite has entered into five technology rights evaluation agreements with commercial partners in using GelSite(R) polymer for drug or vaccine delivery by various routes. These include intranasal delivery of a Shigellosis vaccine by EndoBiologics, Inc.; intranasal delivery of peptide/protein therapeutics by Nastech Pharmaceutical Company, Inc.; injectable delivery of an HIV peptide vaccine by AriaVax, Inc.; injectable delivery of a cancer therapeutic agent by ElSohly Laboratories; and sublingual delivery of vaccines by the International Vaccine Institute.

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SOURCE Carrington Laboratories, Inc.
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