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Caris Life Sciences nimmt Next-Generation Sequencing zur Verbesserung des evidenzbasierten Tumorprofilierungsservices für Krebspatienten auf
Date:1/28/2013

auen oder von der erfolgreichen Nutzung einer bestimmten DNA-Mutation abhängen, ist Caris sowohl technologie- als auch biomarker-agnostisch und verwendet ein breites Spektrum an Technologien zur Entdeckung einer großen Bandbreite von wichtigen Biomarkern. Mit diesem einzigartigen Ansatz bietet das Unternehmen derzeit Informationen über möglicherweise klinisch relevante Beziehungen zwischen Biomarkern und Medikamenten für etwa 95 Prozent der Patienten, d. h., durchschnittlich mehr als 25 mögliche, klinisch verwertbare Biomarker für jeden Patienten.

„Die Auswertung von DNA alleine berücksichtigt nicht die wahre Komplexität der Biologie, die hinter dem Krebs steht. Es ist wichtig, den wesentlichen Einfluss der RNA und nachgelagerter Veränderungen der Proteine einzubeziehen, die an der Krankheit der jeweiligen Patienten beteiligt sind", sagte David D. Halbert, Chairman und Chief Executive Officer von Caris Life Sciences. „Man muss unbedingt eine ganzheitliche und umfassende Analyse eines Tumors durchzuführen, besonders der Proteine, die ja die aktiven Substanzen sind. Alles andere würde für den behandelnden Arzt ein Bärendienst sein und möglicherweise ein Risiko für den Patienten darstellen."

Die Integration des Next-Generation Sequencing zeigt erneut unser Engagement, uns laufend entlang der neuesten Erkenntnisse der Wissenschaft zu entwickeln, um unseren Ärzten einen unübertroffenen, umfassenden Tumorprofilierungsservice bieten zu können", sagt Tom Spalding , Senior Vice President & Group Head, Oncology, von Caris Life Sciences. „Das Ergebnis dieses umfassenden Ansatzes ist, dass wir deutlich größeren klinischen Nutzen als andere Services bieten können, die sich
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