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Caris Life Sciences nimmt Next-Generation Sequencing zur Verbesserung des evidenzbasierten Tumorprofilierungsservices für Krebspatienten auf
Date:1/28/2013

IRVING, Texas, 28. Januar 2013 /PRNewswire/ -- Caris Life Sciences®, ein führendes biowissenschaftliches Unternehmen, das sich auf die Einführung von personalisierter Medizin konzentriert, gab heute die kommerzielle Verfügbarkeit der Mutationsanalyse mithilfe von Next-Generation Sequencing (NGS) bekannt, welche die bisherige Mutationsanalyseplattform ersetzen wird. NGS kommt zu einer bereits umfassenden Sammlung von Tumorprofilierungstechnologien hinzu, die der Caris Molecular Intelligence™ Service (MI Profile™) derzeit einsetzt, und zu denen Immunohistochemie (IHC), Fluoreszenz in situ Hybridisierung (FISH), chromogene in situ Hybridisierung (CISH), Restriktionsfragment-Längenpolymorphismus (RFLP) und Polymerase-Kettenreaktion (PCR) gehören. Damit steht Onkologen die bis heute umfangreichste, kommerziell verfügbare Möglichkeit der Molekularprofilierung zur Verfügung.

MI Profile™ bietet umfassende Biomarkeranalysen von Tumoren und kombiniert diese mit einer weitgehenden Prüfung von Nachweisen in der klinischen Literatur, wobei mögliche Therapien mit patientenspezifischen Biomarkerinformationen verglichen werden. Onkologen erhalten einfach zu lesende Berichte, die auf den Ergebnissen der Molekularprofilierung aufbauen, und aus denen ersichtlich ist, welche chemotherapeutischen, biologischen und hormongestützten Behandlungen potenziell wirksam sind bzw. welche potenziell weniger wirksam sind. Der Bericht enthält ebenfalls Informationen über angebrachte und derzeit rekrutierende klinische Studien, die für den Patienten geeignet wären. Dieser Service bietet Ärzten klinisch relevante, patientenspezifische Informationen, die sie zur Personalisierung ihrer Krebsbehandlungen einsetzen können.

Anders als andere, auf dem Markt befindliche Tumorprofilierungsdienste, die oft nur auf einer einzigen Technologieplattform aufb
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