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Caris Life Sciences erhält erste Akkreditierung als medizinisches Laboratorium nach ISO 15189 im Bereich Tumor-Profiling
Date:12/20/2013

m Einsatz, die sich auf die neuesten und belastbarsten Kenntnisse stützen, darunter Immunhistochemie, Fluoreszenz- und chromogene In-situ-Hybridisierung, Polymerase-Kettenreaktion und Next-Generation-Sequenzierung. Dadurch erhalten Onkologen ein umfassendes, klinisch relevantes Profil der einzigartigen Krebs-Biomarker eines Patienten. Im Gegensatz zu anderen Tumor-Profiling-Diensten fragt Caris Molecular Intelligence™ die individuelle Tumorbiologie eines Patienten vollständiger ab und geht dabei über die reine DNA-Analyse hinaus. Anhand weiterer wichtiger biologischer Komponenten wie RNA- und Proteinexpressions-Ebenen entsteht ein multidimensionales Tumorprofil des Patienten, das genauer auf die komplexen biologischen Prozesse, die den Krebs eines Patienten steuern, schließen lässt und daher relevantere Angriffspunkte für die klinische Behandlung bietet.  

Das multidimensionale Profil des individuellen Tumors eines Patienten wird mit den Erkenntnissen der Caris Molecular Intelligence aus seiner eigenentwickelten, branchenführenden Evidenzpflege- und Bioinformatikplattform zur Identifizierung und Berichterstattung der klinisch relevantesten Assoziationen zu Medikamententherapien abgeglichen, die von der U.S. Food & Drug Administration zugelassen sind oder in den USA in aktiven klinischen Studien untersucht werden. Unter Führung des Caris Evidence Design Board, einem Expertenteam aus 5 PhDs und 6 MDs, werden mit der Caris Molecular Intelligence Evidenz- und Bioinformatikplattform die Erkenntnisse und Evidenz aus allen relevanten klinischen Studien im Bereich Krebs und Krebsbiologie, die in der wissenschaftlichen und medizinischen Literatur veröffentlicht werden, gepflegt, klassifiziert und katalogisiert. Die dabei angewendete Methode ist eine Abwandlung der Evidenzprüfung, wie sie von der U.S. Preventive Services Task Force (

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