Navigation Links
Cardium's Corgentin Preclinical Program Shows High Levels of Targeting to Acutely Ischemic Heart Muscle Following Intracoronary Infusion
Date:3/11/2008

SAN DIEGO, March 11 /PRNewswire-FirstCall/ -- Cardium Therapeutics (Amex: CXM) announced positive findings from its preclinical study being conducted by researchers at Emory University, which demonstrated highly efficient uptake of DNA-based vectors within acutely ischemic myocardium (heart muscle lacking sufficient blood flow as a result of blockage of the coronary arteries). The study employed an occlusion and reperfusion model analogous to a heart attack or acute myocardial infarction, in which the coronary arteries supplying the heart muscle are initially blocked and later reopened, as occurs in patients after a heart attack. In that setting, delivery of an adenovector using Cardium's intracoronary administration technique resulted in robust protein expression within acutely ischemic areas of the myocardium that are most at risk for damage following a heart attack. In addition to showing high levels of uptake, there was no evidence of any increase in inflammatory responses following intracoronary infusion to the acutely ischemic heart as compared to controls.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080311/LATU021)

(Logo: http://www.newscom.com/cgi-bin/prnh/20051018/CARDIUMLOGO)

This study was designed to further support the therapeutic potential of Corgentin(TM) (Ad5IGF-I) to preserve heart tissue and cardiac function following a heart attack and was conducted at Emory University under support of an NIH Small Business Innovation Research (SBIR) grant. Corgentin is a DNA-based therapeutic designed to provide localized and sustained cardiac product
'/>"/>

SOURCE Cardium Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related biology technology :

1. Genmab Announces Encouraging Preclinical Data for ofatumumab
2. Arius Features Preclinical Data on Antibody Candidates at Two Conferences
3. Preclinical Research on Coronary Stent with CeloNova BioSciences Polyzene(R)- F Nanocoating Receives Award at CIRSE 2007
4. Arpida Invited to Present Preclinical Data on Novel Topical Antibiotic AR-2474 at ICAAC
5. Arpida Presents Preclinical and Clinical Data on Iclaprim at ICAAC
6. Arpida Presents Preclinical Data on AR-2474 at ICAAC
7. ADVENTRX to Present ANX-514 Preclinical Data at 2007 AACR-NCI-EORTC International Conference
8. Genta Announces Presentation of New Clinical and Preclinical Data on Genasense(R) at AACR-NCI-EORTC Targets Conference
9. ANX-514 Reduces Hypersensitivity Reactions Without Impacting Pharmacokinetics or Antitumor Activity in Preclinical Tests
10. Preclinical Efficacy Data Demonstrate Ability of Tengions Neo-Bladder Augment to Restore Bladder Function
11. GelVac(TM) Nasal Powder H5N1 (Bird Flu) Influenza Vaccine Passes Preclinical Toxicology Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... -- About POCT POCT, also ... laboratory. It helps in making fast clinical decisions, ... POCT is gaining popularity due to the increasing ... diabetes, heart disease, and obesity. It is generally ... minimize errors during the diagnosis of patients. POCT ...
(Date:9/18/2014)... A novel robotic system that can ... currently being tested as part of a biomedical research ... with the aim of determining if the robot, in ... biopsies faster, more accurate, less costly, and less discomforting ... potential to deliver prostate cancer therapies with greater precision. ...
(Date:9/18/2014)... , September 18, 2014 ... ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has announced the ... - Global Strategic Business Report" ... http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes the worldwide ... Million by the following Product Segments: ...
(Date:9/18/2014)... Washington, D.C. (PRWEB) September 18, 2014 ... Dick Durbin and Sen. Jim Risch for National Lab ... research projects from across the national laboratory system. Durbin ... Caucus, which aims to increase awareness of the reach ... breakthrough technologies and discoveries to address some of our ...
Breaking Biology Technology:POCT Market in China 2014-2018 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3
... RNA Isolation Kit , , ... for molecular assays due to abundant genetic information as ... ease and simplicity of sample collection. RNA , ... MagMAX-96 Blood RNA Isolation Kit uses strong denaturing , ...
... of Long dsRNA for RNAi , ... dsRNA for RNAi experiments in non-mammalian systems can now be , ... The kit , is based on ... and includes reagents for transcription, nuclease digestion and , ...
... RNA later Tissue , ... the preservation of RNA in intact animal tissues, organs, and cells. , ... tissue , samples or to freeze samples ... Here we demonstrate that RNA later provides the , ...
Cached Biology Technology:Robust High Throughput RNA Isolation from Blood Samples 2Robust High Throughput RNA Isolation from Blood Samples 3Robust High Throughput RNA Isolation from Blood Samples 4RNAi in Non-Mammalian Cultured Cells 2RNAi in Non-Mammalian Cultured Cells 3RNAi in Non-Mammalian Cultured Cells 4RNAi in Non-Mammalian Cultured Cells 5RNAi in Non-Mammalian Cultured Cells 6RNAi in Non-Mammalian Cultured Cells 7RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 2RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 3RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis 4
(Date:9/17/2014)... Arlington engineering professor and his doctoral student have designed ... accumulate water collected from fog and dew., The device ... or deserts around the globe., Cheng Luo, professor in ... PhD candidate in the same College of Engineering department, ... edition of ACS, (American Chemical Society) Applied ...
(Date:9/17/2014)... developed, very cleverly, some lessons on how to create ... Joseph Shaw, director of the Optical Technology Center at ... at the nanoscale, we,ll discover them." , Some of ... during a conference called "The Nature of Light: Light ... the University of Arizona College of Optical Sciences. The ...
(Date:9/17/2014)... del Mar Medical Research Institute) and at the Universitat ... in eLife showing that RNA called non-coding ... new proteins, some of which could have important cell ... the instructions found in an RNA molecule. However, only ... for the synthesis of proteins, meaning it is coding. ...
Breaking Biology News(10 mins):Shorebird's beak inspires UT Arlington research on water collection 2Nature's designs inspire research into new light-based technologies 2Nature's designs inspire research into new light-based technologies 3Parts of genome without a known function may play a key role in the birth of new proteins 2
... Public Health Project Eating Among Teens (EAT) researchers ... of encouraging youth to eat breakfast regularly. Researchers ... body weight change in more than 2,200 adolescents, ... consumed a healthier diet and were more physically ...
... Schedule , The following schedule of press conferences ... Sciences Meeting. Press conferences may be added or dropped, ... change. All updates to this schedule will be announced ... Convention Center). Press conferences take place in the Press ...
... Bobev, assistant professor of chemistry and biochemistry, has ... Career Development Award. The highly competitive funding ... educational activities of faculty early in their careers, ... most likely to become the academic leaders of ...
Cached Biology News:U of M finds teens who eat breakfast daily eat healthier diets than those who skip breakfast 22008 Ocean Sciences Meeting -- media advisory 2 22008 Ocean Sciences Meeting -- media advisory 2 32008 Ocean Sciences Meeting -- media advisory 2 42008 Ocean Sciences Meeting -- media advisory 2 52008 Ocean Sciences Meeting -- media advisory 2 62008 Ocean Sciences Meeting -- media advisory 2 72008 Ocean Sciences Meeting -- media advisory 2 82008 Ocean Sciences Meeting -- media advisory 2 9UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 2UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 3
Taq DNA Polymerase (T. aquaticus), 250 units. For PCR and other procedures requiring DNA polymerase activity at elevated temperatures. Category: Nucleotides & Enzymes & Biochemicals, Modifying Enzyme...
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/L; 1 tube of 1, 000 units enzyme/tube w/Buffer II and MgCl2...
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/uL; 25 tubes of 1, 000 units enzyme/tube w/ Buffer I...
A robust formulation of Taq Polymerase supplied with a 10X colored reaction buffer which allows Direct Gel-Loading...
Biology Products: