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Cardiome meldet Veröffentlichung positiver Ergebnisse aus Vergleichsstudie von Vernakalant IV mit Propafenon und Flecainid
Date:9/24/2013

VANCOUVER, September 24, 2013 /PRNewswire/ --

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Die Cardiome Pharma Corp. (NASDAQ: CRME / TSX: COM) meldete heute die Veröffentlichung positiver Ergebnisse aus einer Open-Label-Studie an Patienten mit Vorhofflimmern, in deren Rahmen die therapeutische Anwendung von intravenös verabreichtem Vernakalant (IV) mit oral verabreichtem Propafenon und oral verabreichtem Flecainid verglichen wurde. Bei den mit Vernakalant behandelten Patienten erfolgte die Konversion in den Sinusrhythmus im Median innerhalb von 12 Minuten, während die Propafenon-Gruppe 151 Minuten und die Flecainid-Gruppe 162 Minuten (p<0,01) benötigte. Die Ergebnisse dieser ersten Vergleichsstudie an diesen drei Wirkstoffen sind in der aktuellen Ausgabe der von Experten begutachteten medizinischen Fachzeitschrift Journal of Atrial Fibrillation publiziert worden.

"Ich bin mit den positiven Ergebnissen dieser Studie sehr zufrieden. Sie zeigen, dass die Konversion zum normalen Sinusrhythmus bei Patienten mit jüngst ausgebrochenem Vorhofflimmern durch die Behandlung mit Vernakalant IV schneller zustande kam als bei Propafenon oder Flecainid. Diese beiden Wirkstoffe werden häufig als antiarrhythmische Medikamente verschrieben," erklärte Dr. med. William Hunter, Chief Executive Officer der Cardiome Pharma Corp. "Die in dieser Einrichtung erzielte schnellere Konversionsrate bei intravenös verabreichtem Vernakalant hat im Vergleich zu den beiden anderen Therapien zu kürzeren Aufenthaltszeiten in der Notaufnahme geführt. Wir sind der Auffassung, dass diese Ergebnisse in weiteren Einrichtungen und ähnlichen Patientengruppen weltweit reproduziert werden können."

"Vernakalant IV ist dank seiner schnell einsetzenden Wirkung in diesem
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SOURCE Cardiome Pharma Corp.
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