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Cardio3 BioSciences Completes Patient Enrolment in First Stage of Pivotal Trial of C-Cure(R) in Heart Failure
Date:12/15/2009

rapy.

Dr Christian Homsy, CEO of Cardio3 BioSciences said: "We believe C-Cure holds the promise for a treatment that could fundamentally change the future of heart failure patients, one of the world's greatest medical needs. The fact that we have been able to fully enroll the first stage of the trial two months ahead of schedule speaks to the interest physicians have in this potential new therapy and brings us a step nearer a new treatment for a condition where at present current therapy does not address the underlying cause of the disease."

Heart failure is a serious and common condition in which the heart cannot pump enough blood through the body, leaving the patient debilitated and unable to conduct a normal life. It can result from heart attacks or a number of other causes. Patients suffering from the condition can experience shortness of breath and extreme exhaustion. It affects 20 million patients in Europe, US and Japan and this number is predicted to double by 2020. Therapies available for chronic heart failure aim at slowing down the disease progression, but with the exception of heart transplant, existing drugs or devices do not cure chronic heart failure.

Dr. Jozef Bartunek, Associate Director of the Cardiovascular Center in Aalst, Belgium and Co-Principal Investigator of the C-Cure trial commented: "C-Cure represents a major breakthrough in the field of cardiac regenerative medicine offering the potential of a curative treatment which could save lives and avoid the need for heart transplants. The trial is progressing very well and we look forward to seeing the safety data next year and to beginning the larger second stage to fully examine the efficacy of C-Cure for these patients."

About Cardio3 BioSciences

Cardio3 BioSciences is a leading Belgian biotechnology company specialising in stem cell-based therapies for the treatment of cardiovascular disease. The Company's lead pr
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