Cardica Receives European CE Mark for C-Port Flex A System for Use in Coronary Artery Bypa...( Flex A System Facilitates Minimally ...)

Flex A System Facilitates Minimally Invasive and Robotic-Assisted Coronary

Artery Bypass Surgery

REDWOOD CITY, Calif., Sept. 12 /PRNewswire-FirstCall/ -- Cardica, Inc. (Nasdaq: CRDC) today announced that it has received European CE Mark (Conformite Europeenne) approval for the C-Port(R) Flex A Anastomosis System. The C-Port Flex A system is a variation of Cardica's C-Port(R) xA Distal Anastomosis System product line and further facilitates the automated anastomosis, or attachment of blood vessels and grafts, during less invasive coronary artery bypass graft (CABG) procedures. Recently, two independent groups of leading cardiothoracic surgeons in the U.S. performed minimally invasive, closed-chest bypass procedures using Cardica's C-Port Flex A Anastomosis System and Intuitive Surgical's da Vinci(R) Surgical System.

"We are pleased that the European authorities have approved the use of the Flex A. We continue to receive positive feedback from cardiothoracic surgeons in the U.S. who are using the C-Port Flex A to perform ground-breaking closed- chest and beating heart procedures," said Bernard A. Hausen, M.D., Ph.D., president and chief executive officer of Cardica, Inc. "The C-Port Flex A is designed to enable surgeons to create compliant, reliable anastomoses in sternum-sparing bypass procedures, even in difficult to reach areas of the heart."

The C-Port Flex A system features several innovative modifications to Cardica's C-Port xA system, which is designed to enable automated, reliable and reproducible connections of blood vessels during CABG surgery. The C-Port Flex A system has a flexible, rather than rigid, shaft; is effective in creating compliant anastomoses in vessel
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