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Cardiac Dimensions Announces First Patient Treated in TITAN II Clinical Trial
Date:10/11/2011

or early mortality and repeat hospitalizations. The CARILLON device was easily deployed in a cath lab setting. Notably, we were able to confirm safety and benefit to the patient intra-operatively. The novel CARILLON technology presents an attractive option for this patient's condition and the millions of others who suffer similarly from heart failure. Collaborating with the other investigational sites in completing enrollment in the TITAN II trial will allow the broader clinical community to obtain a robust understanding of this nascent and exciting technology."

About CARILLON® Mitral Contour SystemCardiac Dimensions' CARILLON Mitral Contour System combines a proprietary, implantable device with a percutaneous catheter delivery system. The implantable device consists of a proximal anchor and a distal anchor connected by a shaping ribbon. Utilizing the heart's natural structures, the device is intended to reduce mitral annulus dilatation upon deployment, thereby significantly reducing functional mitral regurgitation (FMR). Rapidly delivered via the venous vasculature, CARILLON has the potential to treat most heart failure patients in a minimally invasive fashion. Early clinical data suggest that usage is associated with significant reduction in FMR, and significant improvement in functional capacity and quality of life.

About Functional Mitral RegurgitationMore than 20 million people worldwide have heart failure, most of whom also suffer from functional mitral regurgitation (FMR). FMR typically results from the dilation of the left ventricle, which is the main pumping chamber in the heart. As the left ventricle increases in size, the mitral valve also expands. This dimensional increase leads to mitral regurgitation, which significantly reduces the amount of blood flow out of the left ventricle and on to the body and its organs. FMR has been associated with high rates of mortality, reduced func
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SOURCE Cardiac Dimensions, Inc.
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