Navigation Links
Capping a two-faced particle gives duke engineers complete control

DURHAM, N.C. Scientists drew fittingly from Roman mythology when they named a unique class of miniscule particles after the god Janus, who is usually depicted as having two faces looking in opposite directions.

For years, scientists have been fascinated by the tantalizing possibilities of these particles for their potential applications in electronic display devices, sensors and many other devices. However, realizing these applications requires precise control over the positions and orientation of the particles, something which has until now eluded scientists.

Duke University engineers say they can for the first time control all the degrees of the particle's motion, opening up broad possibilities for nanotechnology and device applications. Their unique technology should make it more likely that Janus particles can be used as the building blocks for a myriad of applications, including such new technologies as electronic paper and self-propelling micromachines.

Typical Janus particles consist of miniscule spherical beads that have one hemisphere coated with a magnetic or metallic material. External magnetic or electric fields can then be used to control the orientation of the particles. However, this coating interferes with optical beams, or traps, another tool scientists use to control positioning.

The breakthrough of Duke engineers was to devise a fabrication strategy to coat the particle with a much smaller fraction of material. This discovery allows these particles to be compatible with optical traps and external magnetic fields, allowing for total control over the particles' positions and orientations.

"Past experiments have only been able to achieve four degrees of control using a combination of magnetic and optical techniques," said Nathan Jenness, a graduate student who completed his studies this year from Duke's Pratt School of Engineering. He and co-author Randall Erb, also a graduate student, were first authors of a paper appearing online in the journal Advanced Materials. "We have created a novel Janus particle that can be manipulated or constrained with six degrees of freedom."

The researchers have dubbed the unique particles they created "dot-Janus" particles.

Using optical traps on dot-Janus particles, researchers controlled three degrees of movement up and down, left and right, forward and backward, while constraining one degree of rotation - side-to-side tilting. Using magnetic fields, they controlled the remaining two degrees of rotation - forward and backward tilting, and left and right turning.

"The solution was to create a particle with a small cap of cobalt that covers about a quarter of the particle," Erb said. He and Jenness conducted their research in the laboratory of Benjamin Yellen, Duke assistant professor of Mechanical Engineering and Materials Science. "This gave the particle just enough of a magnetic handle to allow it to be manipulated by magnetism without interfering with the optical tweezers."

The researchers said that the fabrication of these unique dot-Janus particles combined with the ability to control their orientation will have important ramifications in the burgeoning field of nanoengineering.

"Being able to more completely control these particles affords us a greater ability to measure the mechanical properties of biomolecules, including DNA," Yellen said. "It may also be possible to control the behavior of cells by manipulating dot-Janus particles attached to cell surfaces. These biological applications, as well as the ability to control the assembly of nanostructures, establish the broad scientific value of these findings."


Contact: Richard Merritt
Duke University

Related biology technology :

1. Spectrum Announces New Distribution of AC-Powered Tool for Crimping and Decapping of Laboratory Vials - The CRIMPenstein™
2. Two-faced miniatures
3. Two-Faced Particles Act Like Tiny Submarines
4. Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug
5. Anthrax vaccine produces immunity with nanoparticles, not needles
6. CeloNova BioSciences Announces Worlds First Line of Fully Color-Coded Embolic Particles at CIRSE: Embozene(TM) Color-Advanced Microspheres
7. New DNA-based technique for assembly of nano- and micro-sized particles
8. New nanoparticle vaccine is more effective but less expensive
9. Anthrax vaccine produces immunity with nanoparticles, not needles
10. Sigma-Aldrich Introduces N-TER Nanoparticle siRNA Transfection System for Delivery of siRNA Into Difficult-to-Transfect Cell Types
11. Researchers outline structure of largest nonvirus particle ever crystallized
Post Your Comments:
Related Image:
Capping a two-faced particle gives duke engineers complete control
(Date:11/27/2015)... ... November 27, 2015 , ... Pittcon is pleased to ... presentations offered in symposia, oral sessions, workshops, awards, and posters. The core ... of applications such as, but not limited to, biotechnology, biomedical, drug discovery, environmental, ...
(Date:11/27/2015)... 2015 --> ... companion diagnostics is one of the major ... pharmaceutical companies and diagnostic manufacturers working together ... . --> ... global cancer biomarkers market spread across 89 ...
(Date:11/26/2015)... MUMBAI , November 26, 2015 ... --> Accutest Research ... accredited Contract Research Organization (CRO), has ... Chase Cancer Center - Temple Health ... ,     (Photo: ) ...
(Date:11/26/2015)... , November 26, 2015 --> ... company specializing in imaging technologies, announced today that it has ... part of the Horizon 2020 European Union Framework Programme for ... large-scale clinical trial in breast cancer. , ... --> --> The study ...
Breaking Biology Technology:
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ( ... "Capacitive Fingerprint Sensors - Technology and Patent Infringement Risk ... --> --> Fingerprint sensors using ... smartphones. The fingerprint sensor vendor Idex forecasts an increase ... in mobile devices and of the fingerprint sensor market ...
(Date:11/20/2015)... -- NXTD ) ("NXT-ID" or the "Company"), ... commerce market and creator of the Wocket® smart wallet, ... interviewed on The RedChip Money Report television ... Bloomberg Europe , Bloomberg Asia, Bloomberg Australia, and ... ) ("NXT-ID" or the "Company"), a biometric authentication company ...
(Date:11/19/2015)... MOUNTAIN VIEW, Calif. , Nov. 19, 2015 /PRNewswire/ ... authentication market, Frost & Sullivan recognizes BIO-key with the ... Strategy Leadership. Each year, Frost & Sullivan presents this ... comprehensive product line catering to the needs of the ... which the product line meets and expands on customer ...
Breaking Biology News(10 mins):