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Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
Date:8/11/2008

nza). StatC(TM) is a combination of two FDA approved compounds which have been re-formulated by Canopus BioPharma for the prevention and treatment of Influenza. Oseltamivir and ribavirin were used as positive controls in this study. In the H5N1 model, StatC(TM) prevented and relieved the symptoms of H5N1 infection, inhibited lung damage and H5N1 virus replication in the lungs of mice, and was as effective as oseltamivir in both prevention and therapy models. There were no animals with positive viral detection in the groups nasally administered with StatC(TM). Likewise, StatC(TM) demonstrated similar results against the H3N2 and H1N1 viruses.

"We are encouraged with these findings," said Dr. Lu. "It is possible that higher doses of statin than those used in this study may result in even greater efficacy. StatC(TM) also appeared to be more effective when administered preventatively." With current positive results, Canopus BioPharma is looking to form a co-development agreement or licensing arrangements with pharmaceutical companies and Government health authorities interested in providing more economical and universal treatment for their populations in the event of a pandemic.

At the forefront of influenza research in Guangzhou, China, Dr. Lu is perfectly placed to further investigate the synergistic properties of the statin/caffeine combination. "We are also motivated at the potential of this compound in comparison with other currently available anti-influenza medications. It's clear that there is significant global need for a superior, low cost and plentiful alternative in the fight against influenza." added Dr. Lu. While StatC(TM) has proven to be highly efficacious against the most virulent strains of influenza, it must be noted that StatC(TM) is also extremely effective against non-fatal, human forms of the virus that occur annually.

Approved by the Food and Drug Administration, oseltamivir (Tamiflu(R)) is the leading prescription medicine ap
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