Navigation Links
Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
Date:8/11/2008

LOS ANGELES, California and GUANGZHOU, China, August 12 /PRNewswire-FirstCall/ --

- Major Threat Treatable With StatC(TM); FDA-Approved Drugs to Begin Testing in U.S. Animal Models

An internationally renowned avian influenza expert today hailed "encouraging and exciting" results from experiments conducted by his research team. This study demonstrated impressive efficacy of a novel statin/caffeine combination, StatC(TM) in the treatment and prevention of H5N1, H1N1 and H3N2 in a mouse model.

To view the Multimedia News Release, please click: http://www.prnewswire.com/mnr/canopusbiopharma/34441/

Dr. Jiahai Lu, from the School of Public Health, Sun Yat-sen University in Guangzhou, China, has published extensively in the field of avian influenza, and has been researching the breakthrough compound StatC(TM) for the past two years on behalf of Canopus Biopharma (OTCPK:CBIA), a US corporation who discovered and patented the potential of this antiviral candidate.

"The global distribution of the highly pathogenic H5N1 avian influenza has caused the World Health Organization to show its profound concern regarding the possibility of the virus spreading from human to human in the future," stated Dr. Lu. "Furthermore, the development of resistance to two approved anti-influenza drugs, oseltamivir (Tamiflu(R)) and zanamivir (Relenza(R)), as well as the lack of adequate vaccines has increased the need of developing new antiviral drugs."

"Consequently, I am delighted to be involved in the preclinical research stage of this innovative antiviral candidate, and look forward to continuing our successful collaboration with Canopus Biopharma in this area."

Dr. Lu and his colleagues have conducted extensive animal studies with StatC(TM) against three influenza strains, H5N1 (avian influenza, bird flu), H1N1 (Spanish influenza) and H3N2 (Hong Kong influenza). StatC(TM) is a combination of two FDA approved compounds which have been re-formulated by Canopus BioPharma for the prevention and treatment of Influenza. Oseltamivir and ribavirin were used as positive controls in this study. In the H5N1 model, StatC(TM) prevented and relieved the symptoms of H5N1 infection, inhibited lung damage and H5N1 virus replication in the lungs of mice, and was as effective as oseltamivir in both prevention and therapy models. There were no animals with positive viral detection in the groups nasally administered with StatC(TM). Likewise, StatC(TM) demonstrated similar results against the H3N2 and H1N1 viruses.

"We are encouraged with these findings," said Dr. Lu. "It is possible that higher doses of statin than those used in this study may result in even greater efficacy. StatC(TM) also appeared to be more effective when administered preventatively." With current positive results, Canopus BioPharma is looking to form a co-development agreement or licensing arrangements with pharmaceutical companies and Government health authorities interested in providing more economical and universal treatment for their populations in the event of a pandemic.

At the forefront of influenza research in Guangzhou, China, Dr. Lu is perfectly placed to further investigate the synergistic properties of the statin/caffeine combination. "We are also motivated at the potential of this compound in comparison with other currently available anti-influenza medications. It's clear that there is significant global need for a superior, low cost and plentiful alternative in the fight against influenza." added Dr. Lu. While StatC(TM) has proven to be highly efficacious against the most virulent strains of influenza, it must be noted that StatC(TM) is also extremely effective against non-fatal, human forms of the virus that occur annually.

Approved by the Food and Drug Administration, oseltamivir (Tamiflu(R)) is the leading prescription medicine approved for the prevention and treatment of influenza in adults and children. Datamonitor, the world's leading provider of online data, analytic and forecasting platforms for key vertical sectors, forecasts that global market demand for influenza treatments will expand to 370 million doses and a market value of approximately $3.7 billion by 2010.

Canopus BioPharma's strategy for developing StatC(TM) includes continued animal testing in partnership with its extensive network of American and Chinese based research laboratories. The next step involves a ferret animal model using a lethal strain of influenza to examine the efficacy of StatC(TM). Once completed, Canopus BioPharma's preclinical results will then satisfy the FDA's Animal Efficacy Rule and will make StatC(TM) available for Government stockpiling for use in the case of a pandemic.

About Canopus BioPharma, Inc.:

Canopus BioPharma, Inc. (OTCPK:CBIA) is dedicated to providing the safest, most cost effective and efficacious pharmaceutical products and assay methods in the areas of infectious disease, radiation protection, cancer, and addiction. With innovative science, proven research and development leadership, and superior products and compounds, Canopus BioPharma has, since 2001, been committed to becoming a market trend setter in a new era of healthcare. In addition, the Company is a world leader in the development of novel camelid antibody products to provide unique avenues of progress and improvement in assay methods and monitoring capabilities for physicians, patients and researchers, particularly for food chain protection applications. Canopus maintains staff in Australia, South Africa, Ireland and the USA. Additional information on the Company is available at http://www.canopusbiopharma.com.

Canopus BioPharma Inc Disclaimer:

With the exception of historical information contained in this press release, content herein may contain "forward looking statements" that are made pursuant to the Safe Harbor Provisions of the Private Securities Litigation Reform Act of 1995. These statements are based on management's current expectations and are subject to uncertainty and changes in circumstances. In particular, the Company may not be successful in its efforts commercialize or attain acceptable clinical results for its products. Investors are cautioned that forward-looking statements involve risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include general economic conditions, delays and risks associated with the performance of contracts and research and development programs, uncertainties as a result of research and development, consumer and industry acceptance, litigation and/or court proceedings, regulatory risks including approval of Food and Drug Administration filings, the ability to achieve and maintain revenues and profitability in the Company's business lines, and other factors discussed in the Company's filings with the Securities and Exchange Commission


'/>"/>
SOURCE Canopus Biopharma INC
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. CB1400, Patented by Canopus BioPharma, Prevents Tumor Growth and Enhances the Anti-Tumor Effects of Cisplatin and Cetuximab (Erbitux).
2. Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Second Quarter 2008 Financial Results on Monday, August 11, at 8:30 A.M. EDT
3. Prometic reaches understanding for commercialisation of several biopharmaceutical products and strategic investment
4. ARCA biopharma Appoints James Carr as Vice President of Marketing
5. TriCipher is First to Transfer Smart Card Level Security to Federally Approved SAFE-BioPharma(TM) Roaming Credentials
6. Keryx Biopharmaceuticals to Present at the Jefferies & Co. Healthcare Conference
7. PacificGMP to Merge With Pacific Biopharma Group and Create Innovative US-Compliant cGMP Contract Biomanufacturing Facility in China
8. Helix BioPharma product development update, quarterly highlights and financial results for fiscal Q3 2008
9. XTL Biopharmaceuticals Announces Appointment of Laurence N. Charney to Board of Directors
10. Best Practices in Quality Assurance and Risk-Based Approach for the Biopharmaceutical Industry
11. XTL Biopharmaceuticals to Present at the Rodman & Renshaw 5th Annual Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... , ... October 10, 2017 , ... San Diego-based team ... its corporate rebranding initiative announced today. The bold new look is part of ... the company moves into a significant growth period. , It will also expand its ...
(Date:10/10/2017)... SomaGenics announced the receipt of a Phase ... (Single Cell), expected to be the first commercially available ... from single cells using NGS methods. The NIH,s recent ... development of approaches to analyze the heterogeneity of cell ... for measuring levels of mRNAs in individual cells have ...
(Date:10/9/2017)... ... 09, 2017 , ... At its national board meeting in North Carolina, ... University’s Departments of Physics and Astronomy, has been selected for membership in ARCS ... for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the accelerating ...
(Date:10/7/2017)... Oct. 6, 2017  The 2017 Nobel Prize ... scientists, Jacques Dubochet, Joachim Frank and ... cryo-electron microscopy (cryo-EM) have helped to ... structural biology community. The winners worked with systems ... routinely produce highly resolved, three-dimensional images of protein ...
Breaking Biology Technology:
(Date:3/30/2017)... March 30, 2017 Trends, opportunities and forecast ... behavioral), by technology (fingerprint, AFIS, iris recognition, facial recognition, ... others), by end use industry (government and law enforcement, ... and banking, and others), and by region ( ... Asia Pacific , and the Rest ...
(Date:3/27/2017)... CENTRE, N.Y. , March 27, 2017 /PRNewswire-USNewswire/ ... Healthcare Information and Management Systems Society (HIMSS) Analytics ... Outpatient EMR Adoption Model sm . In addition, ... 12% of U.S. hospitals using an electronic medical ... CHS for its high level of EMR usage ...
(Date:3/23/2017)... PUNE, India , March 23, 2017 The report ... Equipment, Touchless Biometric), Industry, and Geography - Global Forecast to 2022", published by ... growing at a CAGR of 29.63% between 2017 and 2022. ... ... Logo ...
Breaking Biology News(10 mins):