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Cambridge Major Appoints Professor John Hartwig as Scientific Advisor
Date:10/31/2007

Expertise in Catalysis and Chiral Chemistry Adds to CML's Technical

Excellence

GERMANTOWN, Wis., Oct. 31 /PRNewswire/ -- Cambridge Major Laboratories announces the appointment of University of Illinois Professor John Hartwig as Scientific Advisor. Professor Hartwig is a world renowned expert in the application of catalysis to the synthesis of amines, halogens, and a variety of chiral transformations. His knowledge will play a vital role in advancing Cambridge Major's development of variety of chemical intermediates and Active Pharmaceutical Ingredients. He joins other prominent academics as part of CML's growing International Scientific Advisory Team.

Professor Hartwig's group has developed a series of catalytic reactions for organic synthesis, including palladium-catalyzed aminations of haloarenes, palladium-catalyzed alpha-arylation of carbonyl compounds, hydroaminations of vinylarenes and dienes, iridium-catalyzed enantioselective allylations of amines and alcohols, and the terminal functionalizations of alkanes. In addition, his group has uncovered new elementary organometallic reactions, such as reductive eliminations of amines, ethers and sulfides, insertions of olefins into transition metal amides and alkoxides, and the oxidative addition of ammonia.

John F. Hartwig received his A.B. from Princeton in 1986 and his Ph.D. from the University of California, Berkeley in 1990. Subsequently, he was an American Cancer Society Postdoctoral Fellow at the Massachusetts Institute of Technology and joined Yale University in 1992 where he was awarded the Irenee P. duPont Professorship in Chemistry in 2004. Dr. Hartwig joined the University of Illinois chemistry faculty in 2006 and currently holds the Kenneth J. Rinehart Jr. Professorship. John Hartwig has received numerous awards including an A.C. Cope Scholar (1998) Award, the Leo Hendrik Baekeland (2003) Award, the Thieme-IUPAC Prize in Synthetic Organic Chemistry (2004), the ACS Award in Organometallic Chemistry (2006), and the Tetrahedron Young Investigator Award in Organic Synthesis (2007).

"It has been a pleasure to become part of the synthetic chemistry community in the midwest, and I am looking forward to working with the experienced and skilled group of synthetic chemists at Cambridge Major Laboratories," said John Hartwig, Kenneth L. Rinehart Jr. Professor of Chemistry, University of Illinois.

"We are excited to have Professor Hartwig join our Scientific Advisory Team. His expertise will significantly help us to expedite synthesis of a wide range of pharmacologically active substances and their key intermediates," said Dr. Michael Major, President and CEO of Cambridge Major. "The addition of Professor Hartwig underscores our commitment to scientific excellence, and also our desire to provide our customers innovative and highly relevant chemistry that works."

Cambridge Major Laboratories, Inc. is a service-based chemistry outsourcing partner to the world's leading pharmaceutical and biotechnology companies, producing pharmaceutical intermediates, Active Pharmaceutical Ingredients, and other organic chemicals. Specializing in chemical process development and advanced multi-step organic synthesis, the Company operates two facilities near Milwaukee, Wisconsin including process chemistry laboratories, kilo labs, pilot plants, and complete analytical laboratories. The Company has been FDA inspected and approved for cGMP manufacturing. Visit us at http://www.c-mlabs.com


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