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Calvert Research Licenses Novel Technology to Treat Age Related Macular Degeneration from Tulane University
Date:6/10/2009

d by Calvert T1 combine the known anti-proliferative effects of a somatostatin peptide analog with a cytotoxic drug chemically linked to the peptide, resulting in a dual mechanism drug candidate designed to specifically target and kill abnormal blood vessels found in wet AMD patients.

The lead compound from this technology platform has shown activity in an animal model of AMD. Calvert T1 intends to advance it further through additional preclinical studies using its network of preferred pharmaceutical development service providers including Calvert Laboratories, Inc., a leading contract laboratory offering toxicology, pharmacology, immunology, pharmacokinetic and other preclinical services to the biotechnology and pharmaceutical industry.

Russ C. McLauchlan, Chairman and CEO of Calvert Holdings commented: "We are very pleased to enter into this agreement with Dr. Coy and his colleagues at Tulane to further develop this very promising technology for the treatment of wet AMD. This disease is of growing concern to millions of people as our population ages. Calvert has a strong commitment to work with research universities such as Tulane to advance these research efforts." He added: "Calvert T1 is a continuation of investments in a range of technologies over the last several years. Other investments include the following: CureDM (Lankenau Institute) for diabetes, Auburn University for targeted drug delivery, Pinnacle Pharmaceuticals (University of Virginia) for wound healing, and AcSentient II (now owned by Ista Pharmaceuticals, Inc.) for ocular hypertension/open-angle glaucoma.

About Tulane University:
Tulane University is one of the nation's leading educational and research institutions. Founded in 1834 in New Orleans, Tulane has ten schools and colleges offering degrees in architecture, busi
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Calvert Research Licenses Novel Technology to Treat Age Related Macular Degeneration from Tulane University
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