Navigation Links
Calithera Biosciences Closes $40 Million in Series A Financing
Date:7/8/2010

pand its technology for targeting allosteric activating sites to other enzymes with therapeutic potential in cancer.

"Most drug discovery efforts are focused on identifying drugs that inhibit enzyme function," said Dr. Wells.  "But, interestingly, many cellular enzymes remain dormant until activated.  In the case of caspases, they can be activated on demand by mimicking the natural process with small molecules."

"I am excited about the novel chemical approach that Calithera is taking," said Chris Christoffersen, Ph.D., of Morgenthaler Ventures and Chairman of the Calithera Board.  "The technology to discover small molecules that target binding sites to activate, rather than inhibit, enzymes has the potential to be a powerful and broadly applicable approach to developing innovative therapies across many targets."  

Expert Leadership Team in Place

The management team of Calithera brings to the company both deep scientific expertise and extensive experience in drug development.  

Susan Molineaux, Ph.D., was most recently a founder and Chief Executive Officer of Proteolix, a company that developed proteasome inhibitors.  Proteolix was in late-stage clinical trials with carfilzomib in multiple myeloma when Onyx Pharmaceuticals acquired the company in 2009 for $851 million.  Prior to forming Proteolix, Dr. Molineaux held leadership positions at Rigel Pharmaceuticals and Praecis Pharmaceuticals.  Dr. Molineaux began her career as a scientist in the Immunology group at Merck.  

Mark Bennett, Ph.D., Senior Vice President of Research at Calithera, was Vice President of Research at Proteolix.  Pre
'/>"/>

SOURCE Calithera Biosciences
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Cardio3 BioSciences Reports Positive Three-Month Data From its Clinical Trial of C-Cure(R) in Heart Failure
2. MD Biosciences Offers Occlusion-induced Myocardial Infarct Model for Investigating the Cardio-protection of a Drug Treatment in the Event of Ischemia/reperfusion Injury
3. Neurocrine Biosciences Announces Conference Call and Webcast on Worldwide Agreement With Abbott on Elagolix
4. YM BioSciences appoints Dr. Nick Glover as President and Chief Operating Officer
5. Sangamo BioSciences Announces Presentation at Two Upcoming Investor Conferences
6. YM BioSciences raises US$3.2 million in support of JAK 1/2 program
7. Neurocrine Biosciences to Present at the Jefferies 2010 Global Life Sciences Conference and the 9th Annual Needham Healthcare Conference
8. YM BioSciences enrolls first US patient in Phase II randomized, double-blind brain metastases trial for nimotuzumab
9. Regado Biosciences, Inc. Continues to Expand Its Patent Portfolio By Announcing Issuance of a New Patent for Its Product Candidates, the REG1 and REG2 Anticoagulation Systems
10. Sangamo BioSciences and Collaborators Present Data in Fifteen Presentations Highlighting Broad Therapeutic Applications of ZFP Technology
11. YM BioSciences announces presentations on global nimotuzumab trials at ASCO annual meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... Having access to safe drinking water and ensuring ... corners of the globe. It’s a major priority right ... where many have been sickened by unclean water. , ... of Engineering has been working to improve drinking water ... college for the peasants.” A branch university of the ...
(Date:10/31/2014)... 30, 2014 Caustic soda is utilized in ... polycarbonates. At present, China takes lead in the global caustic ... possesses a number of facilities in the USA, Germany, Brazil ... caustic soda market in terms of output and production capacities. ... on average by 3% per year in the years ahead. ...
(Date:10/31/2014)... The evening of October 29th, ... in successful medical device development to give its ... takes to successfully innovate in the complex and ... two-hour on-site class, Insight gave master’s program students ... School of Engineering, medical and law schools an ...
(Date:10/31/2014)... 30, 2014 Two separate delegations ... hosted by Charm Sciences at its Andover, Massachusetts ... in the US, the participants discussed international systems ... management, and process verification, and received hands-on technical ... was the first visit to the United States ...
Breaking Biology Technology:Fairfield University School of Engineering project reduces illness in rural community 2Fairfield University School of Engineering project reduces illness in rural community 3China to Dominate Caustic Soda Market Through 2018, Says Merchant Research & Consulting in Its New Study 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 3Charm Sciences Hosts Executives from Latin America for Dairy Safety Executive Seminar 2
... Cingular merger with AT&T? , ,I've read the business stories ... the assets and customers of AT&T Wireless for $41 billion. ... 2 carrier Verizon by 9 million subscribers. The one hitch ... brand and plans to launch a new wireless service under ...
... Many organizations talk a good game about interpersonal skills, influence ... there's a pretty clear chain of command that runs right ... Technology (DoIT) at the University of Wisconsin-Madison, Annie Stunden ... that many more staff with IT responsibilities in other departments ...
... in Carlsbad, California. , Dynal : 400+ employees worldwide, ... in Oslo, Norway. Brown Deer, Wis. ... Dynal Biotech ASA , whose U.S. operations are based ... for $380.4 million. , ,Invitrogen has considered the ...
Cached Biology Technology:Cingular confusion 2Cingular confusion 3Annie Stunden, CIO at the University of Wisconsin-Madison 2Annie Stunden, CIO at the University of Wisconsin-Madison 3Annie Stunden, CIO at the University of Wisconsin-Madison 4Invitrogen to buy Norwegian biotech with operations in Brown Deer 2
(Date:10/29/2014)... on sunlight to make their food, but they also need ... scientists discovered a group of molecules in plants that shields ... Journal of the American Chemical Society , one team ... work. , Timothy Zwier and colleagues at Purdue University note ... can cause serious damage to plant DNA and, as a ...
(Date:10/29/2014)... available in German . ... Cabral and Peter Schlögelhofer at the Max F. Perutz ... Medical University of Vienna dived into the process of ... plants display an inversion of the standard meiotic phases. ... journal Nature Communications . , Meiosis is the ...
(Date:10/29/2014)... Ghrelin is a hormone released by the stomach and ... viewed as a psychoactive substance that primarily affects brain ... , This knowledge, combined with findings from animal ... the potential to stimulate alcohol craving. , Dr. Lorenzo ... found that, as they had anticipated, alcohol craving was ...
Breaking Biology News(10 mins):Meiotic cell division 'the other way round' 2Ghrelin stimulates an appetite for drinking alcohol 2
... it comes to improving bone health in postmenopausal women ... University researcher has found a simple, proactive solution to help ... career, I have tested numerous fruits, including figs, dates, strawberries ... having the effect on bone density that dried plums, or ...
... , INDIANAPOLIS -- An Indiana University scientist studying human ... the U.S. Department of Defense to study a chemical ... bone healing. Hiroki Yokota, professor of biomedical engineering ... of anatomy and cell biology at the IU School ...
... the first major survey in Asia of a deadly fungus ... worldwide. The massive survey could help scientists zero in on ... of the globe -- and why Asian amphibians have so ... chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis or Bd, is ...
Cached Biology News:No bones about it: Eating dried plums helps prevent fractures and osteoporosis 2New compound may accelerate bone healing, prevent osteoporosis 2New compound may accelerate bone healing, prevent osteoporosis 3Researchers complete first major survey of amphibian fungus in Asia 2
Latanoprost EIA Antiserum EIAs neutrophils antisera enzyme immunoassays reagents...
Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXS6673E protein). [Source:Uniprot/SWISSPROT;Acc:Q14202] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Phospho-SEK1/MKK4 (Thr261) Antibody...
Human Ig Lambda-chain, clone ICO-16, Monoclonal Antibody...
Biology Products: