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Caliper Life Sciences and DiscoveRx Announce Availability of PathHunter eXpress Reagents for GPCR Assays

- PathHunter eXpress Kits Combined with LabChip Microfluidic Instruments Provide a Comprehensive, High Quality, Easy-to-Use GPCR Assay Solution -

HOPKINTON, Mass. and FREMONT, Calif., Oct. 7 /PRNewswire-FirstCall/ -- Caliper Life Sciences, Inc. (Nasdaq: CALP) and DiscoveRx, today announced the commercial availability of PathHunter(TM) eXpress Beta-Arrestin kits for use with Caliper's LabChip(R) 3000 and EZ Reader(TM) platforms to conduct cellular G protein-coupled receptor (GPCR) assays. This milestone is part of the collaboration between Caliper and DiscoveRx, announced in May 2008, to provide a powerful and comprehensive suite of solutions to assist pharmaceutical and biotechnology researchers in more efficiently discovering new drugs.

"This joint solution enables researchers to quickly assess potency and potential side effects of new drug candidates in a cellular environment, which accelerates overall drug discovery programs," said Nate Cosper, Director of Marketing at Caliper Life Sciences. "Achievement of this commercial milestone underscores Caliper's commitment to partnering with leading technology companies like DiscoveRx to develop innovative solutions that provide higher quality and more reproducible data, improve scientific workflows and enable novel research approaches."

Caliper's LabChip 3000 and EZ Reader platforms, a suite of instruments for screening and profiling potential drug candidates, utilize microfluidic separation and direct detection of both substrates and products to generate high quality, reproducible data to qualify potential lead candidates. Caliper provides researchers in neuroscience, cardiovascular, and inflammation therapeutic areas with platforms and services for target validation, receptor screening, side effect profiling, functional cellular assays, in vivo efficacy studies using IVIS technology, and in vivo pharmacodynamic analysis.

"PathHunter eXpress Beta-Arrestin kits for use with Caliper's LabChip instruments contain everything needed to perform screening or profiling experiments: cells, detection reagents, media and plates. The workflow improvements inherent to this complete solution for live-cell GPCR experiments enables scientists to spend more of their time designing better and safer drugs," said Sailaja Kuchibhatla, Senior Vice President of Business Development at DiscoveRx. "Today's announcement further signifies the momentum generated by our partnership with Caliper and the relationships they are helping us develop with customers in secondary screening and profiling laboratories."

About DiscoveRx Inc.

Founded in 2000, DiscoveRx is a privately held, venture-backed company headquartered in Fremont, California, with an additional office in Birmingham, England. The Company pioneered the use of Beta-Galactosidase enzyme fragment complementation in biochemical and cell based assays for discovery research, and holds extensive intellectual property in this area. DiscoveRx is dedicated to the development and commercialization of innovative solutions to study GPCRs, Kinases and other major drug target classes, and many of their innovative products have been widely adopted in pharmaceutical and biotech drug screening laboratories worldwide. For more information on DiscoveRx products, please visit

About Caliper Life Sciences

Caliper Life Sciences is a premier provider of cutting-edge technologies enabling researchers in the life sciences industry to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper is aggressively innovating new technology to bridge the gap between in vitro assays and in vivo results and then translating those results into cures for human disease. Caliper's portfolio of offerings includes state-of-the-art microfluidics, lab automation & liquid handling, optical imaging technologies, and discovery & development outsourcing solutions. For more information please visit

Caliper, LabChip, and EZ Reader are trademarks of Caliper Life Sciences, Inc.

DiscoveRx and PathHunter are trademarks of DiscoveRx Corporation.

SOURCE Caliper Life Sciences, Inc.
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