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Cadence Pharmaceuticals Announces U.S. Launch and Availability of OFIRMEV™ (acetaminophen) Injection
Date:1/18/2011

dies, OFIRMEV demonstrated significant pain relief, reduced the consumption of opioids, and improved patient satisfaction.  OFIRMEV is also the first and only IV medication indicated for the treatment of pain and fever in children two years of age and older.

"We have long needed better tools to improve pain management in hospitalized patients," said Keith Candiotti, M.D., Professor of Anesthesiology at the University of Miami.  "The safety and effectiveness of IV acetaminophen has been well established in numerous clinical trials and has become the foundation of IV pain management in Europe since its introduction in 2002.  I believe that OFIRMEV will meet a longstanding unmet need in the U.S. and expect it to play a prominent role in the treatment of pain not only in my practice, but across the U.S."

Conference Call and Webcast Details

Cadence management will host a conference call and webcast on Tuesday, January 18, 2011 at 1:30 p.m. Pacific Time/ 4:30 p.m. Eastern Time. Interested investors may participate in the conference call by dialing (877) 303-9145 (domestic) or (760) 536-5203 (international). To access the webcast, please visit Cadence's website at www.cadencepharm.com and go to the Investor Relations page. A replay of the webcast will be available approximately two hours after the call and remain available on Cadence's website for 30 days through February 17, 2011.

About OFIRMEV (acetaminophen) Injection

OFIRMEV (acetaminophen) injection is Cadence Pharmaceuticals' proprietary intravenous formulation of acetaminophen. The FDA approval of OFIRMEV was based on data from clinical trials in which a total of 1,020 adult and 355 pediatric patients received IV acetaminophen. These trials included two studies evaluating the safety and effectiveness of OFIRMEV in the management of pain, and one study evaluating OFIRMEV in the treatment of fever.

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SOURCE Cadence Pharmaceuticals, Inc.
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