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CV Therapeutics Announces Presentations at American Heart Association Scientific Sessions 2008

PALO ALTO, Calif., Oct. 21 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX) announced today that five clinical and preclinical abstracts have been accepted for presentation at the American Heart Association (AHA) Scientific Sessions 2008, which will be held in New Orleans, LA on November 8 - 12, 2008.

In addition, company chairman and chief executive officer Louis G. Lange, M.D., PhD. will present The Industry's Perspective on the Pressures, Challenges and Ethics of Conducting Clinical Trials in the Modern Era at an AHA plenary session on November 12, 2008, 9:00 a.m. CST.

The accepted abstracts relate to several different topics, as follows:

Ranexa(R) (ranolazine extended-release tablets):

Ranolazine, a Late Sodium Current Inhibitor, as an Adjunct to Cardioplegia Further Reduces Contracture During Ischemia And Reperfusion; Poster Presentation, Monday, November 10, 2008, 3:00 p.m. CST

Lexiscan(R) (regadenoson) injection

High Reproducibility of Serial Adenosine Single Photon Tomography Myocardial Perfusion Studies: A Quantitative Analysis from the ADVANCE 2 Study; Poster Presentation, Sunday, November 9, 2008, 9:30 a.m. CST

Regadenoson Induces Perfusion Defects of Comparable Extent and Severity as Adenosine: A Quantitative Analysis from the ADVANCE 2 Trial; Oral Presentation, Wednesday, November 12, 2008, 4:15 p.m. CST

Chronic Angina

Long-Term Morbidity and Mortality among Patients with Angina and Multivessel Coronary Artery Disease in the Duke Cardiovascular Databank; Oral Presentation, Tuesday, November 11, 2008, 9:00 a.m. CST

Late Sodium Current

Discordant T Wave and Mechanical Alternans in Left Ventricular Hypertrophy: Role of Late Sodium Current; Poster Presentation, Wednesday, November 12, 2008, 9:00 a.m. CST

Additional information regarding the AHA Scientific Sessions 2008 can be accessed at

About CV Therapeutics

CV Therapeutics, Inc., headquartered in Palo Alto, California, is a biopharmaceutical company primarily focused on applying molecular cardiology to the discovery, development and commercialization of novel, small molecule drugs for the treatment of cardiovascular diseases. CV Therapeutics Ltd. is the company's European subsidiary based in the United Kingdom.

CV Therapeutics' approved products in the United States include Ranexa(R) (ranolazine extended-release tablets), indicated for the treatment of chronic angina in patients who have not achieved an adequate response with other antianginal drugs, and Lexiscan(R) (regadenoson) injection for use as a pharmacologic stress agent in radionuclide myocardial perfusion imaging in patients unable to undergo adequate exercise stress. Ranexa(R) (ranolazine prolonged-release tablets) is approved for use in the European Union as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or intolerant to first-line antianginal therapies. CV Therapeutics also has other clinical and preclinical drug development candidates and programs.

Except for the historical information contained herein, the matters set forth in this press release, including statements as to research and development and commercialization of products, are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially, including operating losses and fluctuations in operating results; capital requirements; regulatory review and approval of our products; special protocol assessment agreement; the conduct and timing of clinical trials; commercialization of products; market acceptance of products; product labeling; concentrated customer base; reliance on strategic partnerships and collaborations; uncertainties in drug development; uncertainties regarding intellectual property and other risks detailed from time to time in CV Therapeutics' SEC reports, including its Quarterly Report on Form 10-Q for the quarter ended June 30, 2008. CV Therapeutics disclaims any intent or obligation to update these forward-looking statements.

SOURCE CV Therapeutics, Inc.
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