Navigation Links
CU-Boulder python study may have implications for human heart health
Date:10/27/2011

arts show significant growth in the major part of the heart that pumps blood, the heart muscle cell size increased, there was no increase in heart fibrosis -- which makes the heart muscle more stiff and can be a sign of disease -- and there were no alterations in the liver or in the skeletal muscles, he said.

"It was remarkable that the fatty acids identified in the plasma-fed pythons could actually stimulate healthy heart growth in mice," said Harrison. The team also tested the fed python plasma and the fatty acid mixture on cultured rat heart cells, with the same positive results, Harrison said.

The CU-led team also identified the activation of signaling pathways in the cells of fed python plasma, which serve as traffic lights of sorts, said Leinwand. "We are trying to understand how to make those signals tell individual heart cells whether they are going down a road that has pathological consequences, like disease, or beneficial consequences, like exercise," she said.

The prey of Burmese pythons can be up to 100 percent of the constricting snake's body mass, said Leinwand, who holds a Marsico Endowed Chair of Excellence at CU-Boulder. "When a python eats, something extraordinary happens. Its metabolism increases by more than forty-fold and the size of its organs increase significantly in mass by building new tissue, which is broken back down during the digestion process."

The three key fatty acids in the fed python plasma turned out to be myristic acid, palmitic acid and palmitoleic acid. The enzyme that showed increased activity in the python hearts during feeding episodes, known as superoxide dismutase, is a well-known "cardio-protective" enzyme in many organisms, including humans, said Leinwand.

The new Science study grew out of a project Leinwand began in 2006 when she was named a Howard Hughes Medical Institute Professor and awarded a four-year, $1 million undergraduate education grant from the Chevy Chase
'/>"/>

Contact: Leslie Leinwand
Leslie.Leinwand@colorado.edu
303-492-7606
University of Colorado at Boulder
Source:Eurekalert  

Page: 1 2 3 4

Related biology technology :

1. Novel CU-Boulder technique shrinks size of nanotechnology circuitry
2. Ultrafast lasers give CU-Boulder researchers a snapshot of electrons in action
3. Study offers clues as to why some patients get infections from cardiac implants
4. Study Hints at Possible Therapeutic Strategy to Combat Premature Birth
5. Revolutionary IVF Study May Change the Way Embryos are Biopsied for Genetic Disease
6. EORTC, BIG, and Agendia Announce Completion of Patient Recruitment for International MINDACT Study
7. HABIT Study Highlights Home BNP Testing May Allow for Earlier Interventions and Better Management of Heart Failure Patient
8. International Study Confirms CNSystems-Technology
9. Childrens Oncology Group and Apeiron to Jointly Conduct Phase II Study in Neuroblastoma With hu14.18-IL2 (APN301)
10. Otonomy Presents Positive New Findings From Phase 1b Study of OTO-104 in Menieres Disease at International Conference
11. BioDelivery Sciences Announces Results from Phase 3 Efficacy Study for BEMA Buprenorphine in Chronic Pain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CU-Boulder python study may have implications for human heart health
(Date:3/2/2015)... 2015  Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a ... medicine, today announced that it will release fourth quarter ... Tuesday, March 10, 2015 after the close of the ... call and webcast on Tuesday, March 10, 2015 at ... the results and recent corporate developments. For ...
(Date:3/1/2015)... (PRWEB) March 01, 2015 Market ... agreement for quality market research promotion on Internet. ... research reports worked out by DataGroup Booksellers. , ... Market Publishers Ltd, commented on the recent partnership ... DataGroup Booksellers in our team of publishers. Since ...
(Date:2/27/2015)... A paper published today, " Financing ... in Science Translational Medicine, demonstrates the ... the risk associated with investing in the treatment ... of funding for developing so-called "orphan" drugs. ... between scientists at the National Center for Advancing ...
(Date:2/27/2015)... 27, 2015  Pfenex Inc. (NYSE MKT: PFNX), a ... therapeutics, today announced that it will be presenting at ... March 2 nd at 3pm PST. Patrick Lucy, chief ... discussing the current state of the biosimilar industry landscape ... For more information on CALBIO 2015 and ...
Breaking Biology Technology:Asterias Biotherapeutics to Report Fourth Quarter and Full Year 2014 Results on March 10, 2015 2Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 2Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4
... June 16 Wyeth (NYSE: WYE ) (the ... Senior Debentures due 2024 (the "Convertible Debentures") have the right ... to their terms effective on the July 15, 2009 purchase ... in aggregate principal amount of Convertible Debentures outstanding. , ...
... SANTA CRUZ, Calif., June 16 Six prestigious members ... Career Center ( www.BioCareerCenter.com ), the nation,s ... science professionals. , , The NIH has the ... in the country. The six NIH organizations that have ...
... Pharmaceuticals, the proprietary products division of a wholly owned ... PRX ), today announced that its development partner, BioAlliance ... the Food and Drug Administration (FDA) for Loramyc (R) ... If approved, Strativa could launch Loramyc in the ...
Cached Biology Technology:Wyeth Announces Holder Right to Surrender Convertible Debentures 2Wyeth Announces Holder Right to Surrender Convertible Debentures 3Wyeth Announces Holder Right to Surrender Convertible Debentures 4National Institutes of Health Join Nation's Leading Postgrad Bio Jobs Board 2National Institutes of Health Join Nation's Leading Postgrad Bio Jobs Board 3Strativa's Development Partner, BioAlliance Pharma, Submits Loramyc(R) NDA 2
(Date:2/23/2015)... NXT-ID, Inc. (NASDAQ: NXTD ... company focused on the growing mobile commerce market, announced ... DISTRIBUTED VOICE DIRECTED PAYMENT METHOD AND SYSTEM. ... groundbreaking payment method. Payment accounts may be selected via ... accessed if both the speech (the word associated with ...
(Date:2/13/2015)... , Feb. 13, 2015 ACT ... company that aims to transform cancer genomic information ... that the company has raised US$ 8 million in ... Based in Taipei, Taiwan , ... ACTDrug™, ACTOnco™. With the aim to implement next ...
(Date:2/11/2015)... 11, 2015 According ... Control Market by Product (Cards and Readers, Biometrics, Controllers, ... Government, Industrial, Healthcare, Education) and By Geography - Global Forecast and ... the Access Control Market is expected to ... a CAGR of 10.6% between 2014 and ...
Breaking Biology News(10 mins):NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3ACT Genomics Raises $8 Million in its First Private Funding Round 2Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4
... lion (Thylacoleo carnifex) would have made mince meat of ... hyper-carnivores ever squared off in a fight to the ... published in the Journal of Zoology suggests that Thylacoleo ... scissor through hide and flesh to produce major trauma ...
... gigantic palm that flowers itself to death and exists as part ... name will be published in the Botanical Journal of the Linnean ... trunk which towers over 18m high and fan leaves which are ... is the most massive palm ever to be found in Madagascar. ...
... (January 16, 2008) The latest medications can delay the ... its devastating effects. This limitation often makes early detection the ... for as long as possible. Now, a new ... University may allow patients to take a brief, inexpensive test ...
Cached Biology News:Marsupial lion tops African lion in fight to death 2New genus of self-destructive palm found in Madagascar 2New genus of self-destructive palm found in Madagascar 3Portable device quickly detects early Alzheimer's 2Portable device quickly detects early Alzheimer's 3
Presenilin-1, N-terminus....
Human Kallikrein 1 MAb (Clone 323803) Protein Family: Serine Proteases...
... are well-characterized tissue-specific stem cells that exhibit ... the life-long maintenance of the hematopoietic system. ... adult bone marrow where hematopoiesis is continuously ... in cord blood, fetal liver, adult spleen ...
MOUSE ANTI PORCINE SLA 1:FITC Immunogen: Porcine peripheral blood mononuclear cells....
Biology Products: