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CTI Announces Data Presentations at the 55th American Society of Hematology Annual Meeting
Date:11/7/2013

on:  Hall E
  • Poster Presentation:  615, Acute Myeloid Leukemia: Therapy, excluding Transplantation: Poster II
  • Abstract #2698
  • A Phase II Study of Tosedostat (TST) in Combination with Either Cytarabine or Decitabine in Newly Diagnosed Older Patients with Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

    • First Author:  Dr. Raya Mawad, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA
    • Date/Time:  Monday, December 9, 2013, 6:00-8:00 p.m. CT
    • Location:  Hall E
    • Poster Presentation:  615, Acute Myeloid Leukemia: Therapy, excluding Transplantation: Poster III
    • Abstract #3926

    Exposure-Response Analysis for Pacritinib (SB1518), a Novel Oral JAK2/FLT3 Inhibitor, In Patients With Myelofibrosis

    • First Author:  Dr. Suliman Al-Fayoumi, Cell Therapeutics, Inc., Seattle, WA
    • Date/Time: Monday, December 9, 2013 at 6:00-8:00 p.m. CT
    • Location:  Hall E
    • Poster Presentation: 634, Myeloproliferative Syndromes: Clinical: Poster III
    • Abstract #4080

    About Pacritinib

    Pacritinib is an oral tyrosine kinase inhibitor (TKI) with dual activity against JAK2 and FLT3.  The JAK family of enzymes are a central component in signal transduction pathways, which are critical to normal blood cell growth and development as well as inflammatory cytokine expression and immune responses.  Mutations in these kinases have been shown to be directly related to the development of a variety of blood related cancers including myeloproliferative neoplasms, leukemia and lymphoma.  Pacritinib may offer an advantage over other JAK inhibitors through effective treatment of symptoms while having
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    SOURCE Cell Therapeutics, Inc.
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