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CORDIS Launches ExoSeal(TM) Vascular Closure Device
Date:5/27/2010

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About the ExoSeal(TM) Vascular Closure Device:

The ExoSeal(TM) Vascular Closure Device is due to be available for the commercial market in June in Europe. Alongside the ExoSeal(TM) Vascular Closure Device launch, Cordis will roll out a comprehensive programme of customer training and certification to ensure that all users are fully confident in the handling of the device.

About the Eclipse Trial

The safety and effectiveness of the device was assessed in two non-randomized studies conducted in Mexico and Germany, as well as a study in the US where the 6F ExoSeal(TM) was compared with manual compression (MC) with a 2:1 randomisation in patients undergoing diagnostic and interventional coronary/peripheral procedures. The trials tested the time to hemostasis, the time to ambulation and the 30-day combined rate of access site-related complications. The results showed that there were no major adverse events, no vascular repair, no access site-related bleeding requiring transfusion, no access site-related infection requiring treatment, no new ipsilateral low extremity ischemia and no surgery for access site-related nerve injury.

    *  Clinical data from the ECLIPSE trial indicates safety in terms of
       vessel injury, access site-related bleeding, infection or nerve
       injury, new ipsilateral lower extremity ischemia or serious adverse
       events (SAE).
    ** In addition to his role as Primary Investigator, Dr. Weimer is
       compensated for his services as a member of the Company's scientific
       advisory board and provides other consulting services.

About Cordis Corporation

For more than 50 years, Cordis Corporation
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