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CEM führt neue, bahnbrechende Technologie für Mikrowellen-Peptidsynthese ein
Date:6/24/2013

engen zur Lead-Optimierung über den Aufbau gezielter Peptid-Bibliotheken bis hin zur Herstellung von 200-Gramm-Mengen für präklinische Studien reicht."

„Die Zykluszeiten sind 10 Mal kürzer als die aktueller Mikrowellen-Synthesizer, so dass Chemiker ein normales Peptid in weniger als einer Stunde herstellen können. Zudem können diese neuen Mikrowellen-Synthesizer dank der schnellen Zykluszeiten ungleich reinere Peptide herstellen", erklärte Collins weiter.

Die zum Patent angemeldete Flex-Add™-Technologie des Systems bietet endlose Volumenlieferung in Verbindung mit höchster Präzision, wodurch die Liberty Blue-Reihe eine Gesamtskala von 0,025 bis 5 mmol abdecken kann, die größte Skala, die Mikrowellen-Synthesizer zu Forschungszwecken je abdecken konnte. Darüber hinaus kann die Chemie dank des neuen Liberty XL direkt auf 100 mmol skaliert werden.

Die Liberty Blue-Reihe der Mikrowellen-Peptidsynthesizer wurde für maximale Geschwindigkeit, Effizienz und besonders einfache Nutzung entwickelt und besteht aus manuellen und automatisierten Systemen sowie Systemen für hohen Durchsatz. Das Liberty XL hingegen ist ein automatisiertes Mittelklasse-System. Die Systeme verfügen über die patentierte Technologie von CEM zur Verwendung von Mikrowellenenergie, sowohl zur Kopplung als auch zur Entschützung der Synthese, wodurch schneller als je zuvor höhere Reinheiten und Erträge erzielt werden können.

„Wir gehen davon aus, dass Liberty Blue und Liberty XL noch größere Auswirkungen auf die Peptidsynthese haben werden als unsere ursprüngliche Mikrowellen-Peptidtechnologie, die für viele Forscher zur ersten Wahl geworden ist. Diese neuen Produkte bieten den Chemikern die Möglichkeit, die Grenzen der Peptidsynthese erneut auszudehnen", schloss Collins.

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SOURCE CEM Corporation
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