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CB1400, Patented by Canopus BioPharma, Prevents Tumor Growth and Enhances the Anti-Tumor Effects of Cisplatin and Cetuximab (Erbitux).
Date:6/19/2008

(Erbitux) alone. An almost 30% increase in efficacy was observed with the addition of CB1400 to cetuximab, increasing tumor inhibition to 89.4%, confirming a synergistic effect of combining the two anti-tumor drugs. Similar to the cisplatin study, there was no significant difference in mean weight or survival between the groups of mice; and no toxicity was observed in this study.

Cetuximab is a chimeric monoclonal antibody, an epidermal growth factor receptor inhibitor used as a chemotherapeutic agent, administered by IV injection for the treatment of various cancers. Enhancing the efficacy of cetuximab may have potential in treating patients no longer responding to traditional chemotherapy.

About Canopus BioPharma, Inc.:

Canopus BioPharma, Inc. (OTCBB: CBIA) is dedicated to providing the safest, most cost effective and efficacious pharmaceutical products and assay methods in the areas of infectious disease, radiation protection, cancer, and addiction. With innovative science, proven research and development leadership, and superior products and compounds, Canopus BioPharma has, since 2001, been committed to becoming a market trend setter in a new era of healthcare. In addition, the Company is a world leader in the development of novel camelid antibody products to provide unique avenues of progress and improvement in assay methods and monitoring capabilities for physicians, patients and researchers, initially for food chain protection applications. Canopus maintains staff in Australia, South Africa, Ireland, Panama and the USA. Additional information on the Company is available at http://www.canopusbiopharma.com.


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SOURCE Canopus BioPharma, Inc.
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