Navigation Links
Butler Hospital Neurologist Lead Author of Ground Breaking Bio-Engineered Treatment Study for Alzheimer's Disease
Date:12/9/2009

PROVIDENCE, R.I., Dec. 9 /PRNewswire/ -- The results of a new study on immune-based treatment of Alzheimer's disease (AD), which was conducted at 30 sites around the country, will be published in the December 15 issue of Neurology®. Lead author, Stephen P. Salloway, MD, MS, director of the Butler Hospital Memory and Aging Program and a professor of neurology and psychiatry at the Warren Alpert Medical School of Brown University, says that this 18-month phase two study on slowing the disease process in Alzheimer's patients offers promising results. The study tested the effectiveness of bapineuzumab, which acts like a vaccine to reduce the levels of toxic amyloid protein thought to play a key role in causing Alzheimer's.

"This study was built from the lab up," says Salloway. While many treatments for Alzheimer's disease have been discovered by observing the impact of treatments for other conditions, this treatment is among the first to use what scientists have developed in the lab to treat the underlying cause of the disease. "This study offers a real step forward in our development of effective treatments for Alzheimer's disease," says Salloway.

The results of the study offer an important piece of the Alzheimer's puzzle. What Dr. Salloway and his colleagues found was that the success of this treatment may be influenced by the patient's genetic makeup. Some people have a genetic marker, called the ApoE e4 gene, which makes them more likely to develop Alzheimer's. This gene increases risk and makes it more likely for people to develop the disease at an earlier age. In this study, people who didn't have the gene responded more positively to the treatment.

Sponsored by Elan Pharmaceuticals and Wyeth Research, the study helped to shape a phase three trial that is now in progress. Based on the results of Salloway's phase two trial, the new study will track patients with the ApoE e4 gene separately from those who do not
'/>"/>

SOURCE Butler Hospital
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. George Butler Joins Bionovos Board of Directors
2. Dr. Robert N. Butler Appointed to Board of Directors of BioTime, Inc.
3. Xceleron Names Michael Butler as President & CEO
4. Six UK Hospitals Join Together in Using Varian Medical Oncology Information Network
5. Largest Asian Cancer Hospital to Evaluate New CT Laser Breast Imaging System
6. Florida Childrens Hospital and Disney Unite to Create Magical Pediatric Hospital
7. Cooler Solutions and Leading Research Hospital to Design Revolutionary Osteoporosis Diagnosis Device
8. AG Mednet Selected By Massachusetts General Hospital to Transport 3D Post-Processing Images
9. National Surgical Hospitals Acquires Majority Share of Houston-Area Surgery Center
10. Candid Details on Hospitals Quality of Care Are Now at Your Fingertips - Just Like It Should Be
11. Anesiva Signs Co-Promotion and Distribution Agreement With Sagent Pharmaceuticals for Zingo(TM) in U.S. Hospitals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 ... advancing patient care in critical areas, announced the closing ... common stock, and warrants to purchase up to an ... price of $4.00 per share and $.01 per warrant.  ... $5.00, are exercisable immediately, and expire 5 years from ...
(Date:12/24/2014)... Missouri (PRWEB) December 23, 2014 GMO ... Swiss biotechnology company, Syngenta, are in the process of ... proceedings. The consolidated case is In Re: Syngenta AG ... U.S. District Court for the District of Kansas. , ... has been handed over to U.S. District Judge John ...
(Date:12/24/2014)... December 23, 2014 According to Ross Selinger, ... Affiliate of ITRA Global, the national office market continues to ... This is evidenced by the third quarter’s surprising 3.9% ... Low energy costs have held inflation down and the ... is the housing market remaining soft. , This solid economic ...
(Date:12/24/2014)... CA (PRWEB) December 23, 2014 Pipette.com ... where their Twitter followers can submit their #HolidayInTheLab pictures ... and their lab mates. , For those struggling to ... mates, the Pipette.com Holiday in the Lab Contest provides ... Pipette.com Twitter followers to send pictures of their ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2
... hand-held medical device will help UK athletes reach the ... competitions. UK Sport, the UK,s high performance sports agency, ... to use cutting edge technology developed by Argento Diagnostics ... will be able to monitor various proteins which reveal ...
... marine biologists and signal-processing experts from Rice University, the ... U.S. universities have won a $6 million grant from ... of nature,s best camouflage artists. Ultimately, the team hopes ... skin colors and patterns produced by marine animals. ...
... benchtop version of the world,s smallest battery its ... a human hair has been created by a team ... To better study the anode,s characteristics, the tiny rechargeable, ... (TEM) at the Center for Integrated Nanotechnologies (CINT), a ...
Cached Biology Technology:Medical science helps UK athletes reach peak performance 2Medical science helps UK athletes reach peak performance 3Nano squid skin: DOD awards $6M for metamaterials research 2Nano squid skin: DOD awards $6M for metamaterials research 3World's smallest battery created at CINT nanotechnology center 2World's smallest battery created at CINT nanotechnology center 3
(Date:12/15/2014)... 12, 2014 Research and Markets ... the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is ... Facial recognition system measures the overall facial feature ... mouth, and the distance between eyes. Facial recognition ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ... Adding functional endpoints to toxicology studies has evolved ...
(Date:12/10/2014)... 9, 2014 CIE San Diego has launched ... the connective tissue that enhances care coordination among social ... share client-level information; earned a second $1 million grant ... serving seniors aging in community and; will be recognized ... 11 th 4-6p. CIE San Diego ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... The discrimination that obese people feel, whether it is ... in the workplace, may have a direct impact on ... University. "Obesity is a physiological issue, but when ... sense of being discriminated againstit can make matters worse ...
... study of 45-million-year-old pollen from Pine Island west of Fort ... geologic history, showing Florida could be 10 million to 15 ... land in Florida during the early Eocene opens the possibility ... that time, including their adaptation, evolution and dispersal until the ...
... Indiana Jones as they search for plants in remote ... of life-saving new medicines, are currently trying to figure ... affect their work. That,s the topic of an article ... C&EN Associate Editor Carmen Drahl explains that ...
Cached Biology News:Stigma weighs heavily on obese people, contributing to greater health problems 2UF Pine lsland pollen study leads to revision of state's ancient geography 2UF Pine lsland pollen study leads to revision of state's ancient geography 3
The filter 695RDF55 Reflect 635 for the Molecular Imager FX is a band pass filter for Cy5 and Alexa Fluor 635 dyes....
... Kit is a 2-color staining method for ... to detect apoptotic cells by flow cytometry. ... required for measuring apoptosis in cells, including ... reagent performance; washing, reaction and rinsing buffers ...
The sample holders for gels are used to hold gels in place in the multi-sample tray I, which is used with Molecular Imager FX imaging systems....
... The ApopTag Fluorescein In Situ ... in situ by the indirect TUNEL ... is conjugated to a Fluorescein reporter ... for 40 samples. Results are analyzed ...
Biology Products: