Navigation Links
Butler Hospital Neurologist Lead Author of Ground Breaking Bio-Engineered Treatment Study for Alzheimer's Disease
Date:12/9/2009

PROVIDENCE, R.I., Dec. 9 /PRNewswire/ -- The results of a new study on immune-based treatment of Alzheimer's disease (AD), which was conducted at 30 sites around the country, will be published in the December 15 issue of Neurology®. Lead author, Stephen P. Salloway, MD, MS, director of the Butler Hospital Memory and Aging Program and a professor of neurology and psychiatry at the Warren Alpert Medical School of Brown University, says that this 18-month phase two study on slowing the disease process in Alzheimer's patients offers promising results. The study tested the effectiveness of bapineuzumab, which acts like a vaccine to reduce the levels of toxic amyloid protein thought to play a key role in causing Alzheimer's.

"This study was built from the lab up," says Salloway. While many treatments for Alzheimer's disease have been discovered by observing the impact of treatments for other conditions, this treatment is among the first to use what scientists have developed in the lab to treat the underlying cause of the disease. "This study offers a real step forward in our development of effective treatments for Alzheimer's disease," says Salloway.

The results of the study offer an important piece of the Alzheimer's puzzle. What Dr. Salloway and his colleagues found was that the success of this treatment may be influenced by the patient's genetic makeup. Some people have a genetic marker, called the ApoE e4 gene, which makes them more likely to develop Alzheimer's. This gene increases risk and makes it more likely for people to develop the disease at an earlier age. In this study, people who didn't have the gene responded more positively to the treatment.

Sponsored by Elan Pharmaceuticals and Wyeth Research, the study helped to shape a phase three trial that is now in progress. Based on the results of Salloway's phase two trial, the new study will track patients with the ApoE e4 gene separately from those who do not carry the gene, further advancing research on the effectiveness of bapineuzumab.

Affiliated with Brown University's Warren Alpert Medical School's Department of Psychiatry, Butler Hospital is a major research, treatment, and teaching center. For more details on the study results visit neurology.org. More information about Butler Hospital's Alzheimer's and other memory disorders research call 401-455-6265, or visit butler.org.

SOURCE Butler Hospital


'/>"/>
SOURCE Butler Hospital
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. George Butler Joins Bionovos Board of Directors
2. Dr. Robert N. Butler Appointed to Board of Directors of BioTime, Inc.
3. Xceleron Names Michael Butler as President & CEO
4. Six UK Hospitals Join Together in Using Varian Medical Oncology Information Network
5. Largest Asian Cancer Hospital to Evaluate New CT Laser Breast Imaging System
6. Florida Childrens Hospital and Disney Unite to Create Magical Pediatric Hospital
7. Cooler Solutions and Leading Research Hospital to Design Revolutionary Osteoporosis Diagnosis Device
8. AG Mednet Selected By Massachusetts General Hospital to Transport 3D Post-Processing Images
9. National Surgical Hospitals Acquires Majority Share of Houston-Area Surgery Center
10. Candid Details on Hospitals Quality of Care Are Now at Your Fingertips - Just Like It Should Be
11. Anesiva Signs Co-Promotion and Distribution Agreement With Sagent Pharmaceuticals for Zingo(TM) in U.S. Hospitals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... ... June 23, 2016 , ... UAS ... the launch of their brand, UP4™ Probiotics, into Target stores nationwide. The company, ... proud to add Target to its list of well-respected retailers. This list includes ...
(Date:6/23/2016)... , June 23, 2016 /PRNewswire/ - FACIT ... Ontario biotechnology company, Propellon Therapeutics ... development and commercialization of a portfolio of first-in-class ... Epigenetic targets such as WDR5 represent an exciting ... significantly in precision medicine for cancer patients. Substantial ...
(Date:6/23/2016)... Houston Methodist Willowbrook Hospital has signed ... to serve as their official health care provider. ... will provide sponsorship support, athletic training services, and ... volunteers, athletes and families. "We are ... and to bring Houston Methodist quality services and ...
(Date:6/23/2016)... 23, 2016  The Prostate Cancer Foundation (PCF) is pleased to ... faster cures for prostate cancer. Members of the Class of 2016 were selected ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
Breaking Biology Technology:
(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
(Date:4/15/2016)... , April 15, 2016  A new ... make more accurate underwriting decisions in a fraction ... timely, competitively priced and high-value life insurance policies ... screenings. With Force Diagnostics, rapid testing ... lifestyle data readings (blood pressure, weight, pulse, BMI, ...
Breaking Biology News(10 mins):