Navigation Links
Building better bone replacements with bacteria
Date:9/6/2009

Bacteria that manufacture hydroxyapatite (HA) could be used to make stronger, more durable bone implants. Professor Lynne Macaskie from the University of Birmingham this week (7-10 September) presented work to the Society for General Microbiology's meeting at Heriot-Watt University, Edinburgh.

Using Serratia bacteria, the research showed that the bacterial cells stuck tightly to surfaces such as titanium alloy, polypropylene, porous glass and polyurethane foam by forming a biofilm layer containing biopolymers that acted as a strong adhesive. The HA coating then builds up over the surface. For practical use, the HA layer must stick tightly, then the material is dried and heated to destroy the bacteria. A micro-manipulation technique used to measure the force needed to overcome the bioglue adhesion showed that dried biofilm stuck 20-times more tightly than fresh biofilm. When coated with HA the adhesion was several times more again. Slightly roughening the surface made the bioglue much more effective.

Currently bone implant materials are made by spraying-on hydroxyapatite. This does not have good mechanical strength and the spraying only reaches visible areas. This biocoating method reaches all the hidden surfaces as the bacteria can "swim" into hidden nooks and crannies. Bacterial HA also has better properties than HA made chemically as the nanocrystals of HA produced by the bacteria are much smaller than HA crystals produced chemically, giving them a high mechanical strength.

"The bacteria are destroyed by heating, leaving just the HA stuck to the surface with their own glue - rather akin to a burnt milk-saucepan," said Professor Macaskie, "We need to do more work actually to turn the materials into materials we can use in biomedicine and the environment. Then they need to be tested in real life situations with clinical and environmental trials."


'/>"/>

Contact: Dianne Stilwell
diannestilwell@me.com
44-795-720-0214
Society for General Microbiology
Source:Eurekalert

Page: 1

Related biology technology :

1. Secret of sandcastle construction could help revive ancient building technique, researchers say
2. Arts Way Manufacturing Announces Launch of New Web Site For Arts Way Scientific - Buildings For Science
3. Techstreet Launches BuildingBlocks Utility for Industry Standards Saving Time and Increasing Productivity for Engineers
4. Photo-catalytic, self cleaning coating for building exteriors
5. PointCross Releases Catalyst for Building Business-Ready SharePoint Solutions in 1/10th the Time
6. AEterna Zentaris Sells Quebec City Building for $7.1 million
7. Alexandria Real Estate Equities, Inc. Features Green Buildings and Sustainable Operations Initiatives and Tour at 2008 BIO
8. Roche Molecular Diagnostics Invests $57.5 Million in Green Research Building
9. University of Maryland, Baltimore BioPark Signs Gliknik Inc. as First Tenant in Its BioInnovation Center in Building Two
10. Millennium Announces 2008 Goals for Growth, Building on Record 2007 Results
11. Siemens Building Technologies Helping Companies Participate in EPA Labs21 Movement With Comprehensive Compliance Solution Strategy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 2016 , ... Researchers at the Universita Politecnica delle Marche in Ancona combed ... pleural mesothelioma. Their findings are the subject of a new article on the Surviving ... signposts in the blood, lung fluid or tissue of mesothelioma patients that can help ...
(Date:6/23/2016)... , June 23, 2016   Boston Biomedical ... novel compounds designed to target cancer stemness pathways, ... been granted Orphan Drug Designation from the U.S. ... of gastric cancer, including gastroesophageal junction (GEJ) cancer. ... designed to inhibit cancer stemness pathways by targeting ...
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... 23, 2016  The Biodesign Challenge (BDC), a university ... to harness living systems and biotechnology, announced its winning ... New York City . ... showcased projects at MoMA,s Celeste Bartos Theater during the ... MoMA,s senior curator of architecture and design, and ...
Breaking Biology Technology:
(Date:4/19/2016)... DUBAI , UAE, April 20, 2016 ... can be implemented as a compact web-based "all-in-one" system ... in the biometric fingerprint reader or the door interface ... requirements of modern access control systems. The minimal dimensions ... the ID readers into the building installations offer considerable ...
(Date:4/14/2016)... AVIV, Israel , April 14, 2016 ... Behavioral Authentication and Malware Detection, today announced the appointment ... already assumed the new role. Goldwerger,s leadership ... BioCatch, on the heels of the deployment of its ... addition, BioCatch,s behavioral biometric technology, which discerns unique cognitive ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys ... founding CEO, Barrett Bready , M.D., who returned ... of the original technical leadership team, including Chief Technology ... of Product Development, Steve Nurnberg and Vice President of ... to the company. Dr. Bready served as ...
Breaking Biology News(10 mins):