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BugLab Launches Noninvasive Biomass Monitor for Continuous, On-Line Measurements
Date:7/8/2008

DANVILLE, Calif., July 8 /PRNewswire/ -- BugLab LLC, has introduced the BugEye 200 Noninvasive Biomass Monitor, a novel biomass measurement system with the widest linear range of any such device currently available. It performs automated, continuous, real-time optical density (OD) measurements of biomass for fermentation and cell culture applications. The BugEye 200 is designed for use in both research laboratory and industrial environments and has a sensor that is easily secured to the outside of a variety of different fermentor types, from small glass vessels to large stainless steel vessels with glass viewing ports. Since no immersion port is required, it avoids fouling and contamination and the need for sensor sterilization is also eliminated. Due to its simple implementation, the BugEye 200 has the lowest total cost of ownership of any biomass monitor currently available.

The BugEye 200 consists of a sensor head that attaches to the fermentor, and a base unit that interfaces with included software, allowing tracking of fermentation progress in real time in any desired units (OD, g/L, cells/mL, etc.) and tracking important events during the fermentation. The system has serial RS-232, USB and two 4-20 mA analog outputs and can function as a stand-alone device or can be controlled through software via serial or USB protocols, enabling straightforward integration into a fermentor control system. Due to the highly linear response of the sensor to changes in biomass, growth rate can be rapidly determined, and is output both as analog and digital output signals.

Most immersion probes for measuring biomass are limited in the range of biomass growth they measure, but the BugEye 200 responds linearly to biomass over a wide range of growth: from less than 0.1 to greater than 300 OD units. It has been tested and shown effective in measuring several microorganisms and cultures including e. coli, yeast, and animal cell cultures. This new monitor will pro
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