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Boston Scientific Begins PLATINUM PLUS Trial for PROMUS(R) Element(TM) Stent System
Date:5/25/2010

Madrid, Spain. Results are expected to be presented in 2012.

"We are very enthusiastic about beginning the first large-scale randomized trial that compares the new platinum chromium PROMUS Element Stent with the XIENCE PRIME Stent," said Dr. Fajadet. "The results should demonstrate how two distinct stent platforms, with the same everolimus drug, perform in a head-to-head comparison."

The PROMUS Element Stent is designed specifically for coronary stenting. The novel stent architecture and proprietary platinum chromium alloy combine to offer greater radial strength and flexibility. The stent architecture helps create consistent lesion coverage and drug distribution while improving deliverability, which is enhanced by an advanced catheter delivery system. The higher density alloy provides superior visibility and reduced recoil while permitting thinner struts compared to prior-generation stents[1].

The PLATINUM PLUS trial is coordinated by the Centre Europeen de Recherche Cardiovasculaire (CERC) under the direction of Marie-Claude Morice, M.D. CERC is an interventional cardiology clinical research organization based in Paris.

"This is an important study that could provide insights on the potential benefits of third-generation drug-eluting stents in an all-comers trial reflecting the daily clinical practice of interventional cardiologists," said Dr. Morice.

The PLATINUM PLUS trial will provide data that may complement Boston Scientific's PLATINUM clinical trial, which completed enrollment of 1,531 patients at 133 sites worldwide in September 2009. PLATINUM is a randomized, controlled, pivotal trial designed to support U.S. Food and Drug Administration (FDA) an
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