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Boston Scientific Announces Start of Major European Registry Assessing Different Olimus-Eluting Stents
Date:2/11/2008

PROENCY will provide real-world clinical data on the PROMUS(TM) Stent

NATICK, Mass., Feb. 11 /PRNewswire-FirstCall/ -- Boston Scientific Corporation (NYSE: BSX) today announced that the first patient has been enrolled in its PROENCY (PROMUS(TM), ENdeavor(R) and CYpher(R)) European registry. The registry is the first to observe different 'Olimus'-eluting coronary stents. It will collect real-life clinical outcome data for Boston Scientific's PROMUS(TM) Everolimus-Eluting Coronary Stent and compare them with data from Johnson & Johnson's Cypher(R) Sirolimus-Eluting Stent and Medtronic's Endeavor(R) Zotarolimus-Eluting Stent in patients in routine clinical practice. The PROMUS Stent is a private-labeled XIENCE(TM) V Everolimus-Eluting Coronary Stent System manufactured by Abbott and distributed by Boston Scientific. The PROMUS Stent is an investigational device in the United States with its Premarket Approval (PMA) application currently under review by the U.S. Food and Drug Administration.

"I am excited to enroll the first patient into this innovative new registry," said Professor Christian Hamm, Principal Investigator, Kerckhoff Heart Center, Bad Nauheim, Germany. "We have previously seen efficacy data from clinical trials with the PROMUS, Cypher and Endeavor stents but data from this registry will allow us, for the first time, to comparatively assess the differences between everolimus-, sirolimus- and zotarolimus-eluting stents in patients with simple and complex lesions. This should help clinicians in making the appropriate stent choice for their patients."

The registry will enroll up to 2,500 patients with simple and complex lesions at multiple sites in several European countries. Of the patients at each site, half wi
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