Navigation Links
Boston College receives W.M. Keck Foundation funding for nanoscale optical microscope
Date:2/3/2011

Chestnut Hill, Mass. (2/3/2011) -- Boston College has been awarded a $1 million grant from the W.M. Keck Foundation to support a team of university researchers developing a new microscope that uses a light-guiding "metamedium" to create images that reveal micro- and macroscopic matter with significantly improved clarity.

The nanoscale coaxial optical microscope, or NCOM, would join a new class of microscopes known as "superlenses," which function far differently than traditional optical microscopes. These new devices use novel technologies to manipulate light, reconstruct it on computers or assemble bits of images to create one in its entirety.

The NCOM, under development in a $1.8 million project, relies on a bundle of hundreds of nanoscale tubes similar in design to the coaxial cable that supplies TV, Internet and phone signals. The nanocoax design will allow the microscope to focus beams of light on sub-wavelength-sized matter, such as cells or proteins, and then return that light to a camera that presents the image.

"We're excited by the opportunities this grant from the W.M. Keck Foundation provides and grateful for their support," said principal investigator Michael J. Naughton, Ferris Professor of Physics at BC. "We believe our novel concepts and ideas on microscopy can lead to the development of the nanoscale coaxial optical microscope, which will have a far-reaching impact on scientific investigation."

Based in Los Angeles, the W. M. Keck Foundation was established in 1954 by the late W. M. Keck, founder of the Superior Oil Company. The Foundation's grant making is focused primarily on pioneering efforts in the areas of medical research, science and engineering and undergraduate education. The Foundation also maintains a Southern California Grant Program that that provides support for the Los Angeles community, with a special emphasis on children and youth. For more information, please visit the foundation website www.wmkeck.org.

In addition to Naughton, the research team includes Professor of Physics Krzysztof Kempa, Joshua Rosenberg, PhD, manager of the University's microscopy imaging facility, and Greg McMahon, PhD, a researcher and nanolithography specialist in the University's Clean Room Nanofabrication Facility.

Tiny pieces of matter present a significant challenge to microscopy because they can be smaller than the wavelengths of the electromagnetic waves that strike them. An optical barrier known since the 1800's as the diffraction limit restricts the resolution, or clarity, necessary to distinguishing among the features of matter. Researchers have traditionally used electron microscopes to "see" matter using electron waves, which can be much shorter than light waves, or optical devices after a sample has been colored with fluorescent dyes. Rosenberg says the advantage of the NCOM will be the ability to examine matter using visible light or photons without the need to manipulate or stain the sample.

Where traditional microscopes offer a resolution that allows scientists to distinguish between two features as long as they are separated by 200 nanometers or more, the NCOM is projected to provide resolution of 20 nanometers. Without the need to manipulate or treat the sample, tissue could be examined in its living state, instead of in the vacuum of an electron microscope.

"With super resolution microscopy, we propose we can achieve 20 nm resolution, which is a 10-fold improvement," said Rosenberg. "That means scientists will be able to see with much finer detail what is going on inside of a cell and how the cell works."


'/>"/>

Contact: Ed Hayward
ed.hayward@bc.edu
617-552-4826
Boston College
Source:Eurekalert  

Related biology technology :

1. Boston Scientific Announces Court Decision
2. Boston Scientific to Participate in UBS Global Life Sciences Conference
3. Boston Scientific Announces FDA Approval of TAXUS(R) Express2(TM) Atom(TM) Stent System, First Drug-Eluting Stent For Small Vessels
4. Video: Boston Scientific Announces FDA Approval of Second-Generation TAXUS(R) Liberte(R) Drug-Eluting Stent
5. Boston Scientific Provides Update on Involuntary Selling of Its Stock by Co-Founders
6. Boston Scientific Provides Comments Reinforcing Strength of Its Balance Sheet
7. Boston Scientific Announces Results for Third Quarter Ended September 30, 2008
8. Boston Healthcare Appoints Adam Barak as Vice President Enhancing Its International Pricing and Reimbursement Capability
9. InterMune to Present at Deutsche Bank Biotech Boston Confab
10. FDA Approves Boston Scientifics Apex(TM) PTCA Dilatation Catheter
11. Idenix Pharmaceuticals to Present at Deutsche Banks 2008 Biotech Boston Confab
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Boston College receives W.M. Keck Foundation funding for nanoscale optical microscope
(Date:2/12/2016)... FRANKLIN LAKES, N.J. , Feb. 12, 2016 /PRNewswire/ ... a leading global medical technology company, today announced the ... Advances in Genome Biology and Technology (AGBT) Meeting. ... BD CLiC System enables genomic research by providing cost ... BD CLiC System is a high-throughput, fully integrated, next ...
(Date:2/11/2016)... NBIX ) today announced its financial results for the quarter ... --> For the fourth quarter of 2015, the ... per share, compared to a net loss of $19.4 million, or ... the year ended December 31, 2015, the Company reported a net ... to a net loss of $60.5 million, or $0.81 loss per ...
(Date:2/11/2016)... ATLANTA , Feb. 11, 2016  Spectra BioPharma ... Organization (CSO) that provides biopharma companies the experience, ... implement and deploy outsourced sales teams. Created in ... team addresses both the strategic and tactical needs ... innovative sales solutions through both personal and non-personal ...
(Date:2/11/2016)... 2016 --> ... (OTCQB: PSID), a life sciences company focused on ... subsidiary, which markets the Caregiver® FDA-cleared non-contact thermometer, ... January 2016, including entering into agreements with five ... growth, and establishing several near-term pipeline opportunities. ...
Breaking Biology Technology:
(Date:1/25/2016)... SEATTLE , Jan. 25, 2016  Glencoe Software, ... biotech, pharma and publication industries, will provide the data ... Phenotypic Screening Centre (NPSC). ... Phenotypic analysis ... even whole organisms, allowing comparisons between states such as ...
(Date:1/20/2016)... --  MedNet Solutions , an innovative SaaS-based eClinical technology ... is pleased to announce the attainment of record-setting corporate ... of the company,s laser focus on (and growing international ... comprehensive, easy-to-use and highly affordable cloud-based technology platform. ... growth achievements in 2015 include: , Record ...
(Date:1/13/2016)... 2016 http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ... the  "India Biometrics Authentication & Identification ...  report to their offering.  ... the addition of the  "India Biometrics ... & Forecast (2015-2020)"  report to ...
Breaking Biology News(10 mins):