Navigation Links
Boston College receives W.M. Keck Foundation funding for nanoscale optical microscope

Chestnut Hill, Mass. (2/3/2011) -- Boston College has been awarded a $1 million grant from the W.M. Keck Foundation to support a team of university researchers developing a new microscope that uses a light-guiding "metamedium" to create images that reveal micro- and macroscopic matter with significantly improved clarity.

The nanoscale coaxial optical microscope, or NCOM, would join a new class of microscopes known as "superlenses," which function far differently than traditional optical microscopes. These new devices use novel technologies to manipulate light, reconstruct it on computers or assemble bits of images to create one in its entirety.

The NCOM, under development in a $1.8 million project, relies on a bundle of hundreds of nanoscale tubes similar in design to the coaxial cable that supplies TV, Internet and phone signals. The nanocoax design will allow the microscope to focus beams of light on sub-wavelength-sized matter, such as cells or proteins, and then return that light to a camera that presents the image.

"We're excited by the opportunities this grant from the W.M. Keck Foundation provides and grateful for their support," said principal investigator Michael J. Naughton, Ferris Professor of Physics at BC. "We believe our novel concepts and ideas on microscopy can lead to the development of the nanoscale coaxial optical microscope, which will have a far-reaching impact on scientific investigation."

Based in Los Angeles, the W. M. Keck Foundation was established in 1954 by the late W. M. Keck, founder of the Superior Oil Company. The Foundation's grant making is focused primarily on pioneering efforts in the areas of medical research, science and engineering and undergraduate education. The Foundation also maintains a Southern California Grant Program that that provides support for the Los Angeles community, with a special emphasis on children and youth. For more information, please visit the foundation website

In addition to Naughton, the research team includes Professor of Physics Krzysztof Kempa, Joshua Rosenberg, PhD, manager of the University's microscopy imaging facility, and Greg McMahon, PhD, a researcher and nanolithography specialist in the University's Clean Room Nanofabrication Facility.

Tiny pieces of matter present a significant challenge to microscopy because they can be smaller than the wavelengths of the electromagnetic waves that strike them. An optical barrier known since the 1800's as the diffraction limit restricts the resolution, or clarity, necessary to distinguishing among the features of matter. Researchers have traditionally used electron microscopes to "see" matter using electron waves, which can be much shorter than light waves, or optical devices after a sample has been colored with fluorescent dyes. Rosenberg says the advantage of the NCOM will be the ability to examine matter using visible light or photons without the need to manipulate or stain the sample.

Where traditional microscopes offer a resolution that allows scientists to distinguish between two features as long as they are separated by 200 nanometers or more, the NCOM is projected to provide resolution of 20 nanometers. Without the need to manipulate or treat the sample, tissue could be examined in its living state, instead of in the vacuum of an electron microscope.

"With super resolution microscopy, we propose we can achieve 20 nm resolution, which is a 10-fold improvement," said Rosenberg. "That means scientists will be able to see with much finer detail what is going on inside of a cell and how the cell works."


Contact: Ed Hayward
Boston College

Related biology technology :

1. Boston Scientific Announces Court Decision
2. Boston Scientific to Participate in UBS Global Life Sciences Conference
3. Boston Scientific Announces FDA Approval of TAXUS(R) Express2(TM) Atom(TM) Stent System, First Drug-Eluting Stent For Small Vessels
4. Video: Boston Scientific Announces FDA Approval of Second-Generation TAXUS(R) Liberte(R) Drug-Eluting Stent
5. Boston Scientific Provides Update on Involuntary Selling of Its Stock by Co-Founders
6. Boston Scientific Provides Comments Reinforcing Strength of Its Balance Sheet
7. Boston Scientific Announces Results for Third Quarter Ended September 30, 2008
8. Boston Healthcare Appoints Adam Barak as Vice President Enhancing Its International Pricing and Reimbursement Capability
9. InterMune to Present at Deutsche Bank Biotech Boston Confab
10. FDA Approves Boston Scientifics Apex(TM) PTCA Dilatation Catheter
11. Idenix Pharmaceuticals to Present at Deutsche Banks 2008 Biotech Boston Confab
Post Your Comments:
Related Image:
Boston College receives W.M. Keck Foundation funding for nanoscale optical microscope
(Date:11/25/2015)... 2015 The Global Genomics ... professional and in-depth study on the current state ... ) , The report ... definitions, classifications, applications and industry chain structure. The ... markets including development trends, competitive landscape analysis, and ...
(Date:11/24/2015)... 24, 2015 Halozyme Therapeutics, Inc. (NASDAQ: HALO ) ... New York on Wednesday, December 2 at 9:30 ... president and CEO, will provide a corporate overview. th ... at 1:00 p.m. ET/10:00 a.m. PT . Jim ... provide a corporate overview. --> th Annual Oppenheimer ...
(Date:11/24/2015)... 2015  Clintrax Global, Inc., a worldwide provider of clinical research ... announced that the company has set a new quarterly earnings record ... quarter growth posted for Q3 of 2014 to Q3 of 2015. ... Mexico , with the establishment of an Asia-Pacific ... United Kingdom and Mexico ...
(Date:11/24/2015)... York , November 24, 2015 ... a recent market research report released by Transparency Market ... to expand at a CAGR of 17.5% during the ... Prenatal Testing Market - Global Industry Analysis, Size, Volume, ... the global non-invasive prenatal testing market to reach a ...
Breaking Biology Technology:
(Date:10/26/2015)... Calif. , Oct. 26, 2015  Delta ID ... biometric authentication to mobile and PC devices, announced its ... smartphone, the arrows NX F-02H launched by NTT DOCOMO, ... NX F-02H is the second smartphone to include iris ... technology in ARROWS NX F-04G in May 2015, world,s ...
(Date:10/23/2015)... and GOLETA, California , ... HFES conference, BIOPAC and SensoMotoric Instruments (SMI) announce a ... eye tracking data captured during interactive real-world tasks ... and play integration of their established wearable solutions for ... to synchronize gaze behavior captured with SMI Eye ...
(Date:10/22/2015)... Calif., Oct. 22, 2015  Synaptics (NASDAQ: SYNA ), a ... its first quarter ended September 30, 2015. ... of fiscal 2016 grew 66 percent over the comparable quarter last ... fiscal 2016 was $23.8 million, or $0.62 per diluted share. ... for the first quarter of fiscal 2016 grew 39 percent over ...
Breaking Biology News(10 mins):