Navigation Links
Bone Biologics Announces UCB-1 (NELL-1) Bone Growth Protein Production Process With Aragen Biosciences
Date:2/24/2009

Produces 98% pure protein

THOUSAND OAKS, Calif., Feb. 24 /PRNewswire/ -- Bone Biologics, Inc. announced today that it's contract research and development organization, Aragen Bioscience, has completed development of a recombinant cell line and initial production process for UCB-1 (NELL-1) recombinant protein.

Bone Biologics has been developing the protein as a platform technology since 2004, leveraging the previous ten years of research in the lab performed by the founding scientists at UCLA. The mechanism of action is not only identified as to how it works, but why, through this exhaustive research effort. This platform technology is combined with DBX(R) demineralized bone matrix to promote bone growth in spinal fusion.

Aragen has produced UCB-1 (NELL-1) at a purity level Bone Biologics believes is sufficient for IDE submission. Results in animal trials using that protein have exhibited rapid bone growth, high quality of bone, and no ectopic bone growth. Efforts will now focus on scaling that process up to produce clinical grade product.

The platform technology will be subject to the FDA review and approval process, including clinical trials. It is not currently approved for use in humans.

Rick Srigley, CEO of Aragen Bioscience said, "This project has been exciting for us. UCB-1 (NELL-1) is a complex and challenging protein, but we believe that the cell line and process we have developed for Bone Biologics can be scaled up to provide protein at purity and productivity levels sufficient for Phase I clinical studies." William Jay Treat, Ph.D., President of Southwest BioProcessing Associates LLC, who has extensive experience in cell line development, scale-up optimization and commercial manufacturing provided key guidance during this process to Bone Biologics, said, "The professionalism, expertise, and awareness of keeping to a timeline by Aragen
'/>"/>

SOURCE Bone Biologics, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. FDA Accepts Amgens Submission and Files Biologics License Application for Denosumab
2. Insmed Sells Follow-on Biologics Platform to Merck & Co., Inc. for Gross Proceeds of $130 Million
3. Interface Biologics secures $5mm financing and appoints Thomas P. Reeves President and Chief Executive Officer
4. DSM Biologics and Crucell Announce Commercial PER.C6(R) Licensing Agreement with Gedeon Richter
5. Savient Submits Biologics License Application (BLA) for pegloticase
6. Therapure Biopharma Inc. announces collaboration with Induce Biologics Inc.
7. Cell Therapeutics Submits Supplemental Biologics License Application for Zevalin Use in First-Line Consolidation Therapy
8. DSM Biologics and MorphoSys AG to Manufacture Fully Human Antibody
9. NuVasive Completes Acquisition of Osteocel Biologics Business
10. Pinnacle Biologics Announces Agreement With pharmexx to Expand Sales Support Activities in Key European Markets
11. Pinnacle Biologics Announces Opening of Executive Offices in Bannockburn, Illinois and the Addition of Sandra Miller to the Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... August 27, 2014 Riviera Beach, ... announcing the creation of the Sancilio Scientific Advisory ... the SCI’s philosophy of looking to nature for ... development actions are based on sound scientific data, ... Advisory Board provides a vehicle for SCI to ...
(Date:8/27/2014)... State College, PA (PRWEB) August 27, 2014 ... Electromagnetic Simulation Software with new features for the ... release is an enhanced Biological Thermal Sensor, exclusive to ... is a specialty version of XFdtd, developed to calculate ... MATLAB® export functionality has been added to all versions ...
(Date:8/26/2014)... 2014  NeuroSigma, Inc., a Los Angeles ... technologies, today announced that it has filed a registration ... Exchange Commission relating to a proposed initial public offering ... be offered and the price range for the proposed ... LLC will act as the book-running manager for the ...
(Date:8/26/2014)... 2014 - A team of engineers from Singapore ... sensor network (WSN) for satellite communications. , With ... in satellite design, constructing a lightweight, low power-consuming, ... inside the satellite has always been a challenge ... the Satellite Research Centre of Nanyang Technological University ...
Breaking Biology Technology:New Sancilio & Company, Inc. Scientific Board 2New Sancilio & Company, Inc. Scientific Board 3Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 3ZigBee in the Sky 2
... HAVEN, Conn., Sept. 9 Rib-X Pharmaceuticals, ... focused on the,discovery and development of novel ... today the formation of its,Clinical Advisory Board. ... will provide oversight and counsel on matters ...
... announces the,availability of MarketStats for agri-biotech equities ... offers a perspective on the,aforementioned equities and ... blogs and opinions., Investors can view ... division of FiSpace.net, a dynamic social networking ...
... Affitech AS, the Norwegian,antibody therapeutics company, today announced ... Chairman of its Board of Directors. The,Company,s previous ... of the,Board. Mr Broymer welcomed Dr McCullagh,s appointment ... McCullagh has agreed to take over from me ...
Cached Biology Technology:Rib-X Pharmaceuticals, Inc. Announces Formation of Clinical Advisory Board 2Rib-X Pharmaceuticals, Inc. Announces Formation of Clinical Advisory Board 3SectorWatch.biz Issues MarketStats on Agri-Biotech Equities YGYB, GRO, SEED, MON, ADM, and BG 2Affitech Appoints Dr. Keith McCullagh as Chairman 2Affitech Appoints Dr. Keith McCullagh as Chairman 3
(Date:8/25/2014)... that promotes virus entry into cells also has the ... viruses, University of Missouri researchers have found. , "This ... our understanding of not only HIV infection, but also ... M.D., Ph.D., associate professor in the MU School of ... study was recently published in the Proceedings of ...
(Date:8/25/2014)... reproduces by manipulating the behavior of ants emits ... brain of its natural target host, but not ... shows., The findings, which suggest that the fungus ... the molecular mechanisms underlying this phenomenon, according to ... to secrete chemicals that affect their environment," noted ...
(Date:8/25/2014)... 25, 2014 Riddell, the leader in football ... Research Institute (TGen), a leader in cutting-edge genomic ... University and its Sun Devil football program will ... to advance athlete concussion detection and treatment. , ... project will combine molecular information and head impact ...
Breaking Biology News(10 mins):MU researchers discover protein's ability to inhibit HIV release 2MU researchers discover protein's ability to inhibit HIV release 3Zombie ant fungi 'know' brains of their hosts 2Zombie ant fungi 'know' brains of their hosts 3Riddell, TGen team with ASU football to further genetic research into concussion detection 2Riddell, TGen team with ASU football to further genetic research into concussion detection 3
... Harvard Medical School (HMS) report in the April 23 ... encode the values that subjects assign to different items. ... of decision-making that occurs when someone chooses between different ... in various parts of the brain respond to separate ...
... up to $10.3 million to help develop a new prosthetic arm ... Utah work is a key part of a U.S. Department of ... device for soldiers and potentially others whose arms were amputated. , ... thoughts, that allows you to feel both the outside world and ...
... depression by manipulating the neurotransmitter serotonin in the brain ... that are not yet understood, say scientists from Georgetown ... That's because the investigators found, for the first time, ... immune system, and that the chemical is specifically used ...
Cached Biology News:Attention shoppers: Researchers find neurons that encode the value of different goods 2Attention shoppers: Researchers find neurons that encode the value of different goods 3Both alcoholism and chronic smoking can damage the brain's prefrontal cortex 2Both alcoholism and chronic smoking can damage the brain's prefrontal cortex 3Both alcoholism and chronic smoking can damage the brain's prefrontal cortex 4Both alcoholism and chronic smoking can damage the brain's prefrontal cortex 5Commonly used antidepressants may also affect human immune system 2Commonly used antidepressants may also affect human immune system 3
... Sheep polyclonal to Decorin ( ... Antigen: Synthetic ... to amino acids 6-19 of Human ... molecule bone proteoglycan II). ...
... VSOS-4P, all Programmable and Digital Orbital Shaker. Our ... redesigned to make every day use even easier. ... for up to 4 different programs. Its easy ... program. Furthermore, the VSOS-4P has a pulse operation ...
... enables early selection of the best ... quantitative data for sensitivity, dynamic range, ... Furthermore quantitative antibody fingerprints can be ... your antibodies., The full-service package includes ...
... is a new generation of microarrays to ... enables you to rapidly elucidate alternatively spliced ... relevant for drug discovery. The service combines ... design and customized analysis with Agilents robust ...
Biology Products: