Navigation Links
Boldly illuminating biology's 'dark matter'
Date:7/14/2013

ific Rise; the Homestake Mine in South Dakota; and the Great Boiling Spring in Nevada. From these samples, the team laser-sorted 9,000 cells, from which they were able to reassemble and identify 201 distinct genomes, which then could be aligned to 28 major previously uncharted branches of the tree of life.

"Microbes are the most abundant and diverse forms of life on Earth," said Tanja Woyke, DOE JGI Microbial Program Head and senior author on the Nature publication. "They occupy every conceivable environmental niche from the extreme depths of the oceans to the driest of deserts. However, our knowledge about their habits and potential benefits has been hindered by the fact that the vast majority of these have not yet been cultivated in the laboratory. So we have only recently become aware of their roles in various ecosystems through cultivation-independent methods, such as metagenomics and single-cell genomics. What we are now discovering are unexpected metabolic features that extend our understanding of biology and challenge established boundaries between the domains of life."

To get around the difficulty of growing most microbes in the lab, recent efforts have focused on conducting surveys based on sequencing marker or 16S ribosomal RNA genes that are conserved across microbial lineages because of their essential role as "housekeeping" genescritical for the organism's survival. Genome sequencing of the rest of the genomes of most of these lineages is however proceeding much more slowly. "Microbial genome representation in the databases is quite skewed," said Chris Rinke, DOE JGI postdoctoral fellow and first author of the study. "More than three-quarters of all sequenced genomes fall into three taxonomic groups or phyla but there are over 60 phyla we know of." For the majority of them, however, there are no cultivated members available.

"Based on 16S surveys we know they're out there, but we don't know much about themthat's why we
'/>"/>

Contact: David Gilbert
degilbert@lbl.gov
DOE/Joint Genome Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology technology :

1. "Just Label It" condemns dangerous riders snuck into the Farm Bill by chemical companies working to keep Americans in the dark about their food
2. Discovery of a dark state could mean a brighter future for solar energy
3. Management Matters Series Starts with “Lab Budgeting 101”
4. Mathematicians can conjure matter waves inside an invisible hat
5. Exotic particles, chilled and trapped, form giant matter wave
6. EveryDayMatters.com Aims to Raise Awareness and Coordinate Care Between Mental and Physical Health
7. Relay race with single atoms: New ways of manipulating matter
8. Ampio Pharmaceuticals Awarded Canadian Composition of Matter Patent That Strengthens IP Protection for Its Key Drug Ampion™
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... 2015   GenoSpace , a leading provider ... analysis of genomic and other biomedical data, today ... the company as Vice President of Sales and ... "GenoSpace partners with its customers ... and explore complex sets of genomic, phenotypic and ...
(Date:7/30/2015)... CA (PRWEB) , ... July 30, 2015 , ... ... successful completion of a field clinical study of its canine osteoarthritis stem cell ... with Aratana Therapeutics (Kansas City, KS) and will be marketed in the US ...
(Date:7/30/2015)... 30, 2015 Ascendis Pharma A/S (Nasdaq: ... its innovative TransCon technology to address significant unmet ... a six-month Phase 2 study to evaluate the ... in 53 treatment-naïve, pre-pubertal children with growth hormone ... pleased with the top-line results from our Phase ...
(Date:7/30/2015)... ... July 30, 2015 , ... GEA's ... designed for continuous operation up to 1500 bar. The sanitary design gauge of ... preventing toxic contamination. , The Pony™ NS2006L homogenizer is an ideal solution for ...
Breaking Biology Technology:GenoSpace Introduces Matthew Fischer as Vice President of Sales and Marketing 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 2Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 4Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 6Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 7GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2
... ... , ... (PRWEB) October 21, 2009 -- iLife Americas, LLC, a leading developer and marketer of ... its line of iLife wellness and therapeutic products. Officially opened on September 1, 2009, ...
... -- China Medical Technologies,Inc. (the "Company") (Nasdaq: CMED ), ... advanced in-vitro diagnostic,products, today announced that it will attend the ... October 31, 2009 in Chengdu,China. , , ... China International Medical Equipment Fair, Date: ...
... created a new material that would allow a fingernail-size ... DVDs or 250 million pages of text, far exceeding ... Led by Dr. Jagdish "Jay" Narayan, John C.C. Fan ... director of the National Science Foundation Center for Advanced ...
Cached Biology Technology:iLife Americas, LLC Enters U.S. Wellness and Therapeutic Markets 2China Medical Technologies to Exhibit its Products at China International Medical Equipment Fair in Chengdu, China 2New material could boost data storage, save energy 2
(Date:7/31/2015)... , July 31, 2015 The 10 th ... be held by BGI from October 22-25, 2015, in ... The conference is celebrating its 10 th anniversary this ... of the world,s most influential annual meetings in the ,omics, ... enjoyable scientific gatherings. ICG-10 focuses on recent ...
(Date:7/23/2015)... -- Aware, Inc. (NASDAQ: AWRE ), a leading supplier ... its second quarter ended June 30, 2015.  ... a decrease of 33% compared to $6.8 million in the ... of 2015 was $0.3 million, or $0.01 per diluted share, ... in the same period a year ago.  ...
(Date:7/21/2015)... NEW YORK , July 21, 2015 /PRNewswire/ ... critical systems, as seen in the recent U.S. ... enterprises a solution to the infosec conundrum, but ... data is stored. To address this dilemma, Biometrics-as-a-Service ... of its Biometric Tokenization SDK for third party ...
Breaking Biology News(10 mins):The 10th International Conference on Genomics (ICG-10) to Open in October 2Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4
... CITY After years of working toward this goal, scientists ... isolate cancer stem cells in tumors so they can target ... A research team at the University of Oklahoma led ... a particular protein only appears in stem cells. Until now, ...
... KNOXVILLE -- Two research groups from the University of ... National Science Foundation to create new graduate research and ... The grants, called Integrative Graduate Education and Research Traineeships, ... graduate students to UT Knoxville for two unique programs ...
... University of Nottingham are to investigate the effect of nutrients ... of keeping up our strength as we get old. ... and Health in Derby, want to know what sort of ... to slow down the natural loss of skeletal muscle with ...
Cached Biology News:UT Knoxville wins 2 $3M National Science Foundation research and education grants 2A stronger future for the elderly 2
SHEEP ANTI BOVINE BETA-LACTOGLOBULIN A...
Recorder, 6", 7 Day, 1 Pen, 0 to 100°C, 220V, 50/60 Hz, for 4520, Customer Installed...
... Ambions 96 well Magnetic-Ring Stand is designed ... well U-bottom microplates. The stand has a ... well microtiter plate footprint. The use of ... fast and easy magnetic separation. With this ...
Request Info...
Biology Products: