Navigation Links
Boehringer Ingelheim and Micromet Announce Global Collaboration for Multiple Myeloma BiTE Antibody
Date:5/5/2010

te on the development of the BiTE antibody. Micromet is responsible for discovery of the BiTE antibody and will jointly conduct with Boehringer Ingelheim further pre-clinical studies.  Boehringer Ingelheim is responsible for all manufacturing activities, clinical development and worldwide commercialization subject to Micromet's co-promotion right in the U.S. Micromet will bear the costs up to a pre-defined amount for its preclinical activities. During commercialization Micromet will solely bear the costs for its sales force in the U.S.  All other costs for research, development, manufacturing and commercialization of the BiTE antibody will be borne by Boehringer Ingelheim.

Under the terms of the agreement Boehringer Ingelheim will pay Micromet an upfront cash payment of 5 million euro (approximately $6.6 million). Micromet is eligible to receive development and regulatory milestone payments of up to 50 million euro (approximately $66 million) and tiered low double-digit royalties on product sales outside the U.S. In the U.S. Micromet and Boehringer Ingelheim will jointly co-promote the BiTE antibody with commercial terms commensurate with a profit split.  

About BiTE Antibodies

BiTE® antibodies are designed to direct the body's cytotoxic, or cell-destroying, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. Typically, antibodies cannot engage T cells because T cells lack the appropriate receptors for binding antibodies. BiTE antibodies have been shown to bind T cells to tumor cells, ultimately inducing a self-destruction process in the tumor cells referred to as apoptosis or programmed cell death. In the presence of BiTE antibodies, T cells have been demonstrated to serially eliminate tum
'/>"/>

SOURCE Micromet, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Ingenuity Systems Announces Multi-Year Agreement With Boehringer Ingelheim
2. Rentschler Biotechnologie Announces Cooperation with Boehringer Ingelheim
3. Boehringer Ingelheim and BioSpace Search for Scientists at Career Fair in Boston, Massachusetts
4. More Than Half of Patients Treated for Benign Prostatic Hyperplasia Receive Boehringer Ingelheims Flomax as First-Line Therapy
5. Boehringer Ingelheim Pharmaceuticals, Inc. Receives the NCQA Seal Of Approval
6. Dalton Medicinal Chemistry Partners Achieves Another Milestone in Collaboration with Boehringer Ingelheim (Canada) Ltd.
7. Astellas and Boehringer Ingelheim Reach Settlement Agreement with Ranbaxy on Flomax Patent Case
8. Dalton Medicinal Chemistry Partners Achieves Milestone in Collaboration with Boehringer Ingelheim (Canada) Ltd.
9. Boehringer Ingelheim Receives Top Honor as Worlds Most Respected Biopharmaceutical Employer in Science 2007 Top Employers Survey
10. Micromet Appoints Former Roche Oncology Clinical Leader Jan Fagerberg as Chief Medical Officer
11. Micromet Reports Interim Data from Phase 1 Study of BiTE Antibody MT110 for the Treatment of Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... laureate Herbert Kroemer famously observed, referring to the ... where layers of different materials meet. In today,s ... of metal oxides are becoming increasingly prominent, with ... superconductors, ferroelectrics and multiferroics. Realizing the vast potential ...
(Date:1/15/2014)... FALLS, N.Y., Jan. 15, 2014   Niagara Thermal ... been selected by Buffalo BioBlower Technologies LLC ("B3") as ... SBIR Phase 2 award from the Army Corps of ... system that kills all biological contaminants and destroys VOCs ...
(Date:1/15/2014)... JOSE, California , January 15, 2014 ... cancer, today announced the appointment of Thomas C Reynolds MD, ... 20 years, development experience gained in the biotechnology industry, most ... "I am delighted to welcome Tom at this transformative time ...
(Date:1/15/2014)... A study has been launched to test whether ... could help to tackle the problem of obesity.  This unique ... surgery based in Stowmarket) and academics at University Campus Suffolk ... technology, which is inspired by equipment used to collect data ...
Breaking Biology Technology:A deeper look at interfaces 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4
... EASTON, Mass., March 6 Pressure,BioSciences, Inc. (Nasdaq: ... teleconference to discuss its 2007 financial results and to ... teleconference either,by telephone or through a live web-cast. The ... March 12, 2008, Time: 4:30 p.m. Eastern Daylight ...
... to Support European Partnerships, ALAMEDA, Calif., and ... collaboration with Novartis Pharma AG to give Novartis,access ... Technology Access Program (ETAP). Terms of the collaboration,were ... opening of a,facility in Paris, France to support ...
... Recently the State of,Brandenburg, and the EU, ... Alcat Europe, GmbH, covering marketing and employee costs ... laboratory company located in the BioTech Park in,Hennigsdorf ... food and,chemical sensitivities through the Alcat test method. ...
Cached Biology Technology:Pressure BioSciences, Inc. to Discuss 2007 Financial Results and Provide Business Update 2Singulex Collaborates With Large Pharmaceutical Company in Erenna(TM) Technology Access Program 2European Union, State of Brandenburg, Award Grants to Alcat Europe, GmbH 2
(Date:4/23/2014)... is a technique used to read quickly. It ... skipping non-essential words and/ or sentences. Similarly to ... to quickly "read" genetic information. Genes that need ... the smaller the encoding message, the easier it ... from Instituto Gulbenkian de Cincia (IGC, Portugal) and ...
(Date:4/22/2014)... of Yale researchers will lead a five-year, $3 million ... events is affecting the transport of dissolved organic matter ... say could alter the chemical composition and water quality ... funding from the National Science Foundation,s MacroSystems Biology program, ... the watershed, which begins in Canada and runs through ...
(Date:4/22/2014)... International Science Consortium Ltd.,s nanotechnology expert will present a ... hazard assessment" at the 7th International Nanotoxicology Congress ... Turkey. , Dr. Monita Sharma will outline a ... National Academy of Sciences, " Toxicity Testing in the ... recommends use of non-animal methods involving human cells and ...
Breaking Biology News(10 mins):Cell division speed influences gene architecture 2Connecticut River watershed study will assess impacts of extreme rain events 2Connecticut River watershed study will assess impacts of extreme rain events 3
... 2012 The Crop Science Society of America (CSSA) announces ... their Annual Meetings, Oct. 21-24, 2012 in Cincinnati, OH. Members ... achievements and meritorious service. Only 0.3 percent of the Society,s ... class of CSSA Fellows are: Marc C. Albertsen, ...
... biological cells like a skin. They also surround organelles ... division. Scientists have long known in principle how biomembranes ... a role in maintaining the optimal distance between neighboring ... with the help of computer simulations, scientists of the ...
... Bioluminescence may play a key role in successful foraging ... research published Aug. 29 in the open access journal ... led by Jade Vacqui-Garcia, monitored the diving behaviour of ... Ocean that were also equipped with light detectors. The ...
Cached Biology News:Crop Science Society of America presents 2012 class of fellows 2Crop Science Society of America presents 2012 class of fellows 3Keep your distance! Why cells and organelles don't get stuck 2
... Sequencer 20 System revolutionizes DNA sequencing, delivering ... The Genome Sequencer 20 System includes: ... and consumables for library construction, amplification, and ... de novo assembly The ...
... The RapidVUE is a particle shape and ... has been designed with the utmost simplicity in ... sample delivery module and an optical bench. The ... allows for easy upgrade for different applications such ...
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
... degradation is critical to the maintenance ... regulatory proteins as important and diverse ... heat shock and stress response, antigen ... and ion channels, cell cycle regulation, ...
Biology Products: