Biotech Cools Off in August But Capital Markets Remai... (% % 12/ ...)

Biotech Cools Off in August But Capital Markets Remain Positive

Date:9/1/2009

% % 12/31 12/31 6/30 7/31 8/31 change change Index 2007 2008 2009 2009 2009 Month YTD Burrill Biotech 331.52 300.33 294.09 313.23 309.76 -1.11% 3.14% Select Burrill Large Cap Biotech 437.71 379.7 424.71 452.87 450.36 -0.55% 18.61% Burrill Mid-Cap 201.89 139.39 173.97 178.77 176.26 -1.40% 26.45% Burrill Small Cap 137.6 78.35 82.51 96.13 100.56 4.61% 28.35% NASDAQ 2652.28 1577.03 1835.04 1978.5 2009.06 1.54% 27.40% DJIA 13264.82 8776.39 8447 9171.61 9496.28 3.54% 8.20%

About Burrill & Company

Founded in 1994, Burrill & Company is a San Francisco-based global leader in life sciences with activities in Venture Capital, Private Equity, Merchant Banking and Media. The Burrill family of venture capital funds has over $950 million under management and its merchant banking business is one of the industry leaders in life sciences transactions. Burrill is also the creator, sponsor and facilitator of over a dozen leading industry conferences worldwide and publisher of a range of bio-intelligence reports including the monthly Burrill Report, which tracks the progress of the global biotechnology industry and annual "State of the Industry" report the latest of which is Biotech 2009-Life Sciences: Navigating the Sea Change, the 23rd annual report on the industry. The 470-plus page book contains analysis and perspectives on the performance of the industry in 2008 and projections for 2009 and beyond. (www.burrillandco.com)

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Breaking Biology News(10 mins):BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 2 BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 3 UF to lead national effort to help patients with rare brain disease 2 UF to lead national effort to help patients with rare brain disease 3 Late-surviving megafauna exposed by ancient DNA in frozen soil 2 Late-surviving megafauna exposed by ancient DNA in frozen soil 3 Late-surviving megafauna exposed by ancient DNA in frozen soil 4 PharmaVentures Corporate Advisory Appoints Nikki Watkins as Practice Head Product 26 Portfolio Strategy 13965 1 PharmaVentures Corporate Advisory Appoints Nikki Watkins as Practice Head Product 26 Portfolio Strategy 13965 2 C O R R E C T I O N Clinical Therapeutics 13962 1 C O R R E C T I O N Clinical Therapeutics 13962 2 C O R R E C T I O N Clinical Therapeutics 13962 3 C O R R E C T I O N Clinical Therapeutics 13962 4 C O R R E C T I O N Clinical Therapeutics 13962 5 Kapstone Medical Acquires Exclusive License to New Orthopedic Technology 56715 1 Kapstone Medical Acquires Exclusive License to New Orthopedic Technology 56715 2

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Biotech Cools Off in August But Capital Markets Remai...(% % 12/ ...)