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Biopure Announces 2008 Second Quarter Financial Results
Date:5/21/2008

h the United Kingdom's Medicines and Healthcare Products Regulatory Agency (MHRA) in May and in June 2008. The purpose of the meeting is to clarify the issues outlined in a letter Biopure received in April 2008 from the U.K.'s Commission on Human Medicines regarding the company's application for marketing authorization for Hemopure [hemoglobin glutamer-250 (bovine)], or HBOC-201.

Clinical Program Update

The company's ongoing clinical trial in patients undergoing cardiopulmonary bypass surgery is nearing completion with 56 of 60 patients enrolled.

U.S. Navy

The company continues to support the Naval Medical Research Center's (NMRC) efforts toward lifting the clinical hold on the Navy's investigational new drug application to conduct the pending, proposed clinical trial in trauma patients entitled "Restore Effective Survival in Shock (RESUS)." In addition to the $22.5M funding allocated by Congress for the military to pursue research of HBOC-201 through the RESUS program, the NMRC has received further funding of approximately $3.4 million for the development of HBOC-201 for a project entitled: A Multifunctional Blood Substitute for Field Resuscitation of Polytrauma Combat Casualties with Brain Injury and Concomitant Hemorrhagic Shock. This project is part of the Post Traumatic Stress Disorder/Traumatic Brain Injury Research Program of the Office of the Congressionally Directed Medical Research Programs. The Navy has chosen HBOC-201 as the platform to develop the first multifunction blood substitute for trauma patients.

South Africa

Usage of Hemopure in South Africa is continuing to increase.

Biopure Corporation

Biopure Corporation develops, manufactures and markets pharmaceuticals, called oxygen therapeutics, that are intravenously administered to deliver oxygen to the body's tissues. Hemopure [hemoglobin glutamer -- 250 (bovine)], or HBOC-201, is approved for sale in South Africa for the treatment of surgic
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