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Biopure Announces 2008 Second Quarter Financial Results
Date:5/21/2008

Rotterdam, The Netherlands. The paper concluded that this trial represents an important next step in the clinical development program for this product as a treatment for acute myocardial ischaemia. The accompanying technical report co-authored by Biopure Director of Cardiovascular Research, Gregory Dube, PhD., entitled "HBOC-201: The multi-purpose oxygen therapeutic." appeared in this issue also. The report provides an overview of the attributes of Hemopure and how it could be potentially useful in cardiac indications.

HEM-0115. A paper on the company's HEM-0115 trial, a phase 3 trial in patients undergoing orthopedic surgery, is to be published in the spring edition of the Journal of Trauma Injury, Infection and Critical Care. The paper, entitled, "HBOC-201 as an alternative to blood transfusion: efficacy and safety evaluation in a multicenter phase 3 trial in elective orthopedic surgery," was authored by the principal investigators, Drs. Jonathan Jahr and Colin MacKenzie, and others. HEM-0115 included nearly 700 patients. The trial was designed to reduce and/or eliminate perioperative transfusion in patients who were expected to require transfusion of at least two units of packed red blood cells as part of their procedure. Publication is currently scheduled for June 10, 2008.

Dechra Veterinary Products - Exclusive Distributor

Dechra Veterinary Products was appointed as exclusive distributor for Oxyglobin solution [hemoglobin glutamer-200 (bovine)] or HBOC-301, in the U.S. Oxyglobin is the only FDA-approved treatment for canine anemia, a potentially life-threatening condition. Under the terms of the agreement, Dechra will market Oxyglobin in 60 mL single dose and 125 mL single dose infusion bags. Biopure will continue to manufacture Oxyglobin. Dechra Veterinary Products is a division of Dechra Pharmaceuticals PLC, a London Stock Exchange listed company in international animal healthcare marketing.

MHRA

Biopure expects to meet wit
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