Navigation Links
Bionovo Publishes Discoveries in Predictable Tissue Selectivity for Selective Estrogen Receptor Modulators Platform
Date:1/3/2009

EMERYVILLE, Calif., Jan. 2 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI) announced today results describing predictable estrogen regulatory elements that can be used to identify estrogenic drugs that are safer. The data, published in Molecular and Cellular Endocrinology, showed that the new regulatory elements can distinguish the estrogenic pharmacological activity exerted by different compounds and allow for more accurate prediction of specific tissue effect.

"Selective estrogen modulators (SERMs) are an exciting class of drugs that are used to prevent breast cancer and osteoporosis and differ from estrogens in how they regulate gene transcription," said Dr. Dale Leitman, from the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco. "This study identified gene elements that are activated by SERMs but not by estrogens used in hormone therapy. The identification of these elements, coupled with the understanding of the differential regulation in various tissues by each estrogen receptor subtype, provides a new platform for the discovery of safer estrogenic drugs with SERM-like profiles to prevent and treat a variety of clinical conditions associated with menopause."

The study was conducted by investigators at The Center for Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco in collaboration with scientists at Bionovo.

"The discovery of these selective estrogen regulatory elements strengthens our SERM discovery engine," said Isaac Cohen, Bionovo's Chairman and Chief Executive Officer. "The advantage of the new array, of specific regulatory elements, is manifest in the pharmacological and toxicological insights gained. We can
'/>"/>

SOURCE Bionovo, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Bionovo to Present at A.G. Edwards 2nd Annual Emerging Growth Conference 2007
2. Bionovo Announces Proposed Public Offering of Common Stock
3. Bionovo to Present at the Biotechnology Industry Organization (BIO) Investor Forum
4. Bionovo Announces the Pricing of Public Offering of Shares of Common Stock
5. Bionovo Announces Third Quarter 2007 Financial Results
6. Bionovo to Present at Bank of Montreals 2007 Focus on Healthcare Conference
7. George Butler Joins Bionovos Board of Directors
8. Louis Drapeau Joins Bionovos Board of Directors
9. Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness
10. Bionovo to Present Recent Findings of BN107 and BN108, Its Anticancer Agents, at the American Association of Cancer Research
11. Bionovo Reports First Quarter 2008 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... SHANGHAI , May 6, 2015 Dr ... institute of Massey University, will deliver a speech at the ... 24-25 at the Shanghai New Expo Center.  ... he will introduce to attendees the topic: ,Potato Starch: ... Bulk-ingredients and Smart Foods., Co-editor of a ...
(Date:5/5/2015)... /PRNewswire/ - Aptose Biosciences Inc. (NASDAQ: APTO, TSX: APS) ("Aptose" ... three months ended March 31, 2015 and provided a ... Canadian dollars. Effective July 17, 2014 ... 31 to December 31. As a result of that ... the three months ended March 31, 2015, while the ...
(Date:5/5/2015)... 05, 2015 Hayden-McNeil is ... develop custom course materials for smaller courses. This program ... low as 200 students. , “I’m very excited ... of higher education instructors,” said Jeff McCarthy, Hayden-McNeil president. ... can do our part to make education both more ...
(Date:5/5/2015)... 05, 2015 The Academy of Model ... Indiana, led by Indiana Gov. Mike Pence, has declared ... Foundation will host a Family Fest and aviation themed ... will benefit the Wounded Warrior Project. , National Model ... Model Aeronautics—the country’s foremost organization for model aviation—to celebrate ...
Breaking Biology Technology:Potato Starch: A Potential Source for the Creation of Next Generation Bulk-ingredients and Smart Foods 2Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 2Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 3Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 4Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 5Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 6Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 7Aptose Biosciences Reports Results for the First Quarter Ended March 31, 2015 8Hayden-McNeil Expands Publishing Program to Service Lower Enrollment Courses 2State of Indiana proclaims August 15 as Model Aviation Day 2
... Calif., Sept. 13 NanoSensors,Inc. (OTC Bulletin Board: ... its,Chief Executive Officer, President, Chief Financial Officer and ... entered into a separation,agreement with Dr. Wong dated ... resign from all positions with NanoSensors, including as ...
... 13 Cephalon, Inc. (Nasdaq:,CEPH) today communicated ... selection, dosing and administration for FENTORA(R),(fentanyl buccal ... information,with the medical community to reinforce the ... The letter, issued in collaboration with the ...
... 13 An affiliate of,Phlo Corporation (OTC: ... of its performance/vitality product, AQUISS(TM), in California,has ... region, an expansive and,diverse territory, including both ... the expansion into additional distribution districts,encompassing San ...
Cached Biology Technology:NanoSensors, Inc. Announces Reorganization of Executive Management Team and Redirection of Operations 2NanoSensors, Inc. Announces Reorganization of Executive Management Team and Redirection of Operations 3NanoSensors, Inc. Announces Reorganization of Executive Management Team and Redirection of Operations 4NanoSensors, Inc. Announces Reorganization of Executive Management Team and Redirection of Operations 5Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA 2Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA 3Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA 4Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA 5AQUISS Expands Into Significant New Territory 2
(Date:4/9/2015)... , April 9, 2015 Synaptics Inc. (NASDAQ: ... solutions, announced today that it will report financial results ... April 23, 2015, after the close of market. The ... and investors at 2:00 p.m. PT (5:00 p.m. ET), ... To participate on the live call, analysts and ...
(Date:4/2/2015)... , April 2, 2015 ... DERMALOG by far outperforms the strongest competitors, showing ... high accuracy, the system is capable of a ... speed proves up to be ten times faster ... its runner-up performance.      (Photo: ...
(Date:4/2/2015)... Sweden , April 2, 2015 ... its touch fingerprint sensor FPC1025 from the distributor World ... will commence during Q2 2015 although the major part ... The sensors will be used by smartphone manufacturers in ... 110 MSEK is included in the communicated revenue guidance ...
Breaking Biology News(10 mins):Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2
... sensitive biological experiments is always a delicate affair. ... by Cheryl Nickerson, whose working laboratory aboard the ... miles above the Earth, traveling at some 17,000 ... at Arizona State University,s Biodesign Institute, is using ...
... has gifted the Institute for Genomic Biology (IGB) a ... by the NSF, Ember will be managed by the ... Ember for a while now through the NCSA, mainly ... "It can perform a lot of tasks that our ...
... a deep, dark mystery. That is changing, though, as ... ocean-going creatures. Stanford marine sciences professor and ... technology to enable live feeds of animal movements relayed ... help protect marine ecosystems by revolutionizing how we understand ...
Cached Biology News:International space station plays host to innovative infectious disease research 2International space station plays host to innovative infectious disease research 3International space station plays host to innovative infectious disease research 4International space station plays host to innovative infectious disease research 5International space station plays host to innovative infectious disease research 6New supercomputer to aid genomics research 2Wiring the ocean 2
Troponin I Immunogen: Full length native protein (purified) (Human). Storage: -20 C, Avoid Freeze/Thaw Cycles...
...
Troponin I (22B11)...
... low freezers , Ultima II ... material storage, Ultima II represents the finest, ... general purpose and blood bank configurations, each ... microprocessor control system with built-in voltage boost ...
Biology Products: