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Biomarkers in Late Stage Clinical Trials: Applications, Opportunities and Activities of Leading Players

roteomics, Applied BioSystems, BG Medicine, Covance, Eli Lilly, Pfizer and Astra Zeneca are some of the major companies engaged in collaborative partnerships in the past three years.

• A number of market players have formed strategic alliances for the development and sharing of technology for biomarker applications in the late stage clinical trials.

• Pharmaceutical companies are focusing mainly on cancer biomarkers for use in late stage (Phase III and IV) clinical trials.

Key questions answered• How is the biomarker late stage clinical trials market segmented and what will growth be to 2014?

• What are the major technologies that have emerged such as microarrays, PCR, LC/MS and GC/MS?

• In which areas are the companies focusing while forming strategic alliances with other industrial players?

• What is the competitive landscape and what is the strategic focus of innovator companies, CROs and biomarker specialists?

• What applications are pharmaceutical companies focusing on while conducting late stage biomarker clinical trials?

Companies mentionedAbbott , Astra Zeneca , Bayer Schering Pharma , Boehringer Ingelheim , Bristol-Myers Squibb , Covance , Eisai Co. Ltd , Eli Lilly , GSK , ICON plc , Merck and Co. Inc. , Novartis , Pfizer , Roche , Sanofi-Aventis , Takeda Pharmaceuticals

Table of ContentsBiomarkers in Late Stage Clinical Trials

Executive summary 12

Market dynamics 12

Biomarker activity at leading pharma companies 13

Applications of biomarkers in clinical trials 13

Biomarker market for late stage clinical trials by tools and services 14

Company profiles 15

Chapter 1 Market dynamics 18

Summary 18

Introduction 19

Factors influencing biomarker adoption in clinical trials 22

Investment scenario for late stage clinical trials 22

Cost of clinical trials: early stage v

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