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Biomarkers - Technologies, Markets and Companies
Date:11/30/2011

kers of branched chain amino acid status 179

Biomarkers of caloric restriction 180

Biomarkers of malnutrition 180

Proteomic biomarkers and nutrition 180

Vitamin deficiency as biomarker of disease 181

Vitamin D as a biomarker of disease 181

Vitamin B12 deficiency 181

Biomarkers of gene-environmental interactions in human disease 182

6. Biomarkers of Cancer 183

Introduction 183

The ideal biomarker for cancer 183

Single vs multiple biomarkers of cancer 184

Types of cancer biomarkers 184

HER3 as biomarker of cancer 185

DNA repair biomarkers 185

miRNAs as biomarkers in cancer 185

Circulating miRNAs for cancer detection 187

Diagnostic value of miRNA in cancer 187

Biomarkers of epigenetic gene silencing in cancer 187

Immunologic biomarkers of cancer 188

Molecular diagnostic techniques for cancer 188

Technologies for detection of cancer biomarkers 189

Genomic technologies for cancer biomarkers 189

Cold-PCR 189

Genome analysis at the molecular level 190

Sequencing-based approaches for detection of cancer biomarkers 190

Early detection of tumor suppressor gene mutations 190

Biomarkers of PTEN tumor suppressor gene status 191

HAAH as a biomarker for cancer 191

KRAS as a biomarker of cancer 192

Telomerase as a biomarker of cancer 192

Digital karyotyping for cancer biomarkers 192

LigAmp for detection of gene mutations in cancer 193

Mitochondrial DNA as a cancer biomarker 193

Tissue microarrays for study of cancer biomarkers 193

Molecular fingerprinting of cancer 194

Biomarkers of inflammation in cancer 195

Proteomic technologies for detecting biomarkers of cancer 195

2D PAGE 196

Antibody-based detection of protein biomarkers 196

Aptamer-based molecular probes for cancer biomarker discovery 197

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