Navigation Links
Bioengineers develop bacterial strain to increase ethanol biofuel production
Date:12/10/2010

Georgia, US - A team of Bioengineers in the United States have modified a strain of bacteria to increase its ability to produce ethanol. The research, published in Biotechnology and Bioengineering, reveals how adaptation and metabolic engineering can be combined for strain improvement, a positive development for the biofuel industry.

The team focused their research on Zymomonas mobilis, a bacterium noted for its bio-ethanol producing potential. However, the team believed that ethanol production could be increased through improvement of xylose fermentation.

"Zymomonas mobilis is a superb ethanol producer with productivity exceeding yeast strains by several fold," said lead author Rachel Chen from the Georgia Institute of Technology. "In this study we sought to improve ethanol production by enhancing the ability of Z. mobilis to use and ferment xylose. Fermenting xylose at high concentration could in turn increase ethanol concentration, resulting in much improved productivity."

The team found that by metabolically altering the strain, sugar fermentation time was reduced from over 110 hours to about 35 hours. This improvement in fermentation allowed the strain to ferment higher concentrations of xylose.

"This demonstrated increase in fermentation and xylose utilization enabled us to produce ethanol to a concentration of 9% (w/v), the highest ever shown for this organism in mixed sugar fermentation," said Chen.

This research also investigated the underlying mechanism for the improvement. Interestingly, by adapting a strain in a high concentration of xylose, significant alterations of metabolism occurred.

One noticeable change was reduced levels of xylitol, a byproduct of xylose fermentation which can inhibit the strain's xylose metabolism. In addition, the first step of xylose metabolism, believed to be the rate-limiting step, was accelerated 4-8 times in the adapted strain, with the net effect of chann
'/>"/>

Contact: Ben Norman
Lifesciencenews@wiley.com
44-012-437-70375
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related biology technology :

1. QuantaLife, Inc. Closes $17.2M Series B Financing to Accelerate Application Development for Its Droplet Digital™ PCR Platform and Establish Commercial Operations by 2011
2. Shrink Nanotechnologies Shrink Chips Cell Culturing Unit Enters Into Exclusive Development and Manufacturing Agreement with EV Group to Commercialize the StemDisc Platform
3. Shrink Nanotechnologies Enters Into Exclusive Development and Manufacturing Agreement With EV Group to Commercialize Stem Disc Platform
4. Chimerix Presents Update on CMX001 Development to the World Health Organization Advisory Committee on Variola Virus Research
5. Pitt-led team develops nanoscale light sensor compatible with Etch-a-Sketch nanoelectronic platform
6. Argos Therapeutics to Present Corporate Overview and Next Steps in Clinical Development of Arcelis™ Immunotherapy at Lazard Capital Markets 7th Annual Healthcare Conference
7. Cardium Reports on Third Quarter 2010 Financial Results and Recent Developments
8. Advanced Life Sciences Submits Full Proposal to NIAID for Development of Intravenous Formulation of Restanza as a Biodefense Countermeasure
9. Transgenomic Develops New Assays to Detect EGFR Mutations Using COLD-PCR
10. U.S. Government Grants Awarded for Further Development of Adult Stem Cell Products
11. Building Biotech Technology Transfer Opportunities: Sponsor and Developer Strategies for Success
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... Inc. (NYSE: MDT ) has submitted ... and Drug Administration (FDA) for the use of ... system (including a newly developed catheter) for use ... delivered intravenously to patients with pulmonary arterial hypertension.   ...
(Date:12/24/2014)... GMO corn cases filed across the ... in the process of being consolidated in a Kansas ... In Re: Syngenta AG MIR 162 Corn Litigation, MDL ... District of Kansas. , Management of the Syngenta GMO ... U.S. District Judge John W. Lungstrum.* , As a ...
(Date:12/24/2014)... December 23, 2014 The ... such as its definition, classification, application and ... specification, manufacturing process, and product cost structure. ... applications. The analysis also covers upstream raw ... industry development trend and proposals. In the ...
(Date:12/24/2014)... , Dec. 23, 2014 Vermillion, Inc. ... on gynecologic disease, announced today that investors including ... Birchview Fund LLC and several Vermillion directors have ... shares of Vermillion,s common stock and warrants to ... a private placement.  Under the ...
Breaking Biology Technology:United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5
... 21 Startech,Environmental Corp. (OTC Bulletin Board: ... Company, announced today that the,EnviroSafe Industrial Services ... its original plans for its new recycling-facility ... to install three Plasma Converters Systems,purchased last ...
... Angiotech Pharmaceuticals,Inc. (NASDAQ: ANPI , TSX: ANP), ... announced that it has elected to suspend,enrolment in ... its Vascular Wrap,product candidate in patients undergoing surgery ... an imbalance of infections that have,been observed between ...
... A group of German,investors is about to acquire up ... purchasing price of up to EUR 750,000. The acquisition,will be ... subscribed,to by the investors. It will become effective after the ... and after the capital increase will,have been entered in the ...
Cached Biology Technology:Startech Environmental to Have Three Plasma Converters in Former Pharmaceutical Industry Facility in Puerto Rico 2Startech Environmental to Have Three Plasma Converters in Former Pharmaceutical Industry Facility in Puerto Rico 3Angiotech elects to suspend Vascular Wrap(TM) pivotal clinical trials 2Angiotech elects to suspend Vascular Wrap(TM) pivotal clinical trials 3Angiotech elects to suspend Vascular Wrap(TM) pivotal clinical trials 4Investors Acquire Share in Sangui BioTech GmbH 2
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ... Adding functional endpoints to toxicology studies has evolved ...
(Date:12/10/2014)... 9, 2014  Wake Forest Baptist Medical Center today announced ... School of Medicine. Funding for this $50 million capital ... will be publicly launched next summer. ... former 60 series R.J. Reynolds Tobacco Company complex, adjacent ... begin immediately with plans to be ready to welcome ...
(Date:12/10/2014)... 2014     ...   Jifflenow, a leading ... for business-to-business (B2B) events, today announced a partnership ... near-field communication (NFC), Bluetooth low energy (BLE), and ... , Jifflenow will integrate its meeting ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... Hospital Research Institute (OHRI) and the University of Ottawa have ... Spinal muscular atrophy (SMA), the leading inherited cause of death ... student Melissa Bowerman have found that an enzyme called RhoA ... and blocking this enzyme can greatly increase survival. The study ...
... 2010 Using a novel light activation technique, Scripps Research ... a modest ability to fight specific proteins into virtual protein ... capable of inactivating nearby proteins when triggered by light, could ... researchers with a new set of research tools and options. ...
... of psychopaths appear to be wired to keep seeking a ... The research uncovers the role of the brain,s reward system ... understanding what drives these individuals. "This study underscores ... Dr. Francis S. Collins, director of the National Institutes of ...
Cached Biology News:Study opens new avenue for developing treatments for genetic muscle-wasting disease 2Light activated 'warhead' turns modest molecules into super protein killers 2Light activated 'warhead' turns modest molecules into super protein killers 3Psychopaths' brains wired to seek rewards, no matter the consequences 2Psychopaths' brains wired to seek rewards, no matter the consequences 3
The Econo gradient pump rack is a preassembled rack that is used to hold the components of the Econo gradient pump kits....
... 384-well reaction module is used for nucleic ... with an interchangeable, 384-well reaction module (5-20 ... and control and ramp rates that are ... the iCycler base with 384-well reaction module, ...
... is the cycler that revolutionized thermal ... and swappable blocks ensure consistent results, ... rugged machine is more than just ... new features and upgrades as research ...
... Gene Pulser Xcell microbial system, 100 ... used for electroporation of bacterial and ... main unit, PC module for exponential ... sterile cuvettes (5 each of 0.1 ...
Biology Products: