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Biocept and Clarient Announce Collaboration on First Test for Circulating Tumor Cells and HER2 Status in Breast Cancer Patients
Date:8/24/2011

d potentially other biomarkers, in the future.  OncoCEE-BR™ is the only commercially available CTC test that combines enumeration and cytogenetic characterization.

Ron Andrews, CEO of Clarient, said, "Establishing the ability to perform molecular characterization of peripheral cancer cells from a blood sample takes us one step closer to making cancer a chronic disease.  Biocept's OncoCEE™ platform supports our mission of personalized medicine and care for cancer patients."

Biocept's OncoCEE-BR™ test is expected to have application in several clinical settings, including:

  • At the time of recurrence, and especially in cases where a biopsy may be difficult to obtain, to determine if the patient's HER2 status has changed from the original diagnosis or surgery.
  • Confirmation of HER2 status at the time of original diagnosis or surgery, where tumor tissue analysis was negative for HER2 amplification.  Biocept has demonstrated detection of HER2-amplified CTCs in patients with HER2 negative primary tumors, a finding reported by other groups in the scientific literature.  This suggests that the pathologist may have examined a part of the tumor that was not HER2 amplified for a variety of reasons including tumor heterogeneity, and that treatment with HER2-targeted agents may be justified.  This could be a life-changing event for a breast cancer patient.

About Biocept, Inc.

Biocept Laboratories, headquartered in San Diego, California, is an advanced diagnostic CLIA-certified laboratory services company specializing in the capture, detection, enumeration and molecular analysis of circulating tumor cells (CTCs). Biocept is dedicated to positively impacting the lives of cancer patients through the development of innovative diagnostic products and services. Biocept utilizes innovative and proprietary technologies to deliver clinically relevant an
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SOURCE Biocept, Inc.
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