Navigation Links
Biocept Demonstrates Multiple Phenotypes of Circulating Tumor Cells (CTCs) in Cancer Patients
Date:5/10/2011

SAN DIEGO, May 10, 2011 /PRNewswire/ -- Biocept, Inc., a privately-held laboratory testing company focused on the detection, enumeration and analysis of circulating tumor cells (CTCs) in cancer patients, today announced the publication of a paper describing the identification of different CTC phenotypes using its proprietary Cell Enrichment and Extraction (CEE™) platform.  The paper, appearing in the Journal of Oncology and entitled "Detection of EPCAM-Negative and Cytokeratin-Negative CTCs in Peripheral Blood", supports a growing belief that there are many cancer patients with CTCs that don't meet the standard criteria by which a CTC is defined and, importantly, detected in current practice.  The Biocept technology platform may allow more sensitive and comprehensive CTC tests for cancer patients.

David Hale, Executive Chairman of Biocept, said, "We are very excited with these results, as they support the potential of Biocept's CEE™ platform, not only to provide more sensitivity than current methods and detect more CTCs from the same blood sample, but also to derive more information about, and offer new insights into, a patient's cancer."  He continued, "We are very optimistic that better treatment decisions, and, ultimately, better patient outcomes, will result."  

CTCs are very rare in the blood of cancer patients, ranging from 1 to over a thousand in a standard 10 ml blood sample, which may contain 50-100 billion normal red or white blood cells.  To be able to count or analyze CTCs, an enrichment process is necessary.  Enrichment from blood is typically achieved using antibodies to EpCAM (Epithelial Cell Adhesion Molecule), a protein found on the surface of epithelial cells that enables them to bind to each other and to the extracellular matrix.  CTCs are normally detected after capture using antibodies to cytokeratin (CK), an intracellular structural protein typically found in epithelial cel
'/>"/>

SOURCE Biocept, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Biocept, Inc. Announces New Director Appointment - September 28, 2010
2. Biocept, Inc. Announces Two New Director Appointments
3. Biocept, Inc. Announces CEO and Director Appointments
4. Dune Medicals MarginProbe™ Demonstrates Increased Positive Margin Identification Leading to Reduction in Patients Indicated for Re-excision in Landmark Lumpectomy Surgery Trial
5. Precision Therapeutics ChemoFx® Demonstrates Significant Role in Selection of Chemotherapy Doublets in Non Small Cell Lung Cancer
6. Otonomys OTO-104 Demonstrates Hearing Loss Protection and Hearing Recovery in Preclinical Studies
7. Capasso lab demonstrates highly unidirectional whispering gallery microlasers
8. Integrated Analysis Demonstrates Alpha(1)-Augmentation Therapy Significantly Reduces Loss of Lung Tissue in Patients with AAT-deficiency-related Emphysema
9. Molecular Detections Detect-Ready™ MRSA Assay Demonstrates Strong Performance In Independent Comparative Study From Leading UK Hospital
10. Newly Published Caldolor® Clinical Data Demonstrates 77% Reduction in Fever in Hospitalized Patients
11. Data Published Today Reveal That Novel Oral Therapy Fostamatinib Demonstrates Positive Response in Rheumatoid Arthritis Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... Texas , Dec. 24, 2014  Vermillion, ... focused on gynecologic disease, announced today that the ... investors including Oracle Investment Management, Jack W. ... directors. Total proceeds were $10.5 million, before offering ... capital and general corporate purposes. Under ...
(Date:12/24/2014)... 2014 “Preparative & Process Chromatography ... Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), Accessories, ... - Forecasts to 2019” provides a detailed overview ... market trends, and strategies impacting the preparative and ... forecasts of the revenue and share analysis. ...
(Date:12/24/2014)... Boston, MA (PRWEB) December 23, 2014 ... presentation, Dr. James L. Sherley, director of the Adult ... attention on an often overlooked and under appreciated unique ... “Asymmetric Self-Renewal by Distributed Stem Cells: Misunderstood in the ... his message to congress participants. He gave the ...
(Date:12/24/2014)... 2014 On Friday, December 19, ... the Omnibus and Continuing Resolution Appropriations Act of ... a condition eligible to receive funding through the ... the Department of Defense (DoD). The Hydrocephalus Association ... Capitol Hill, is celebrating this victory for the ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2
... PRINCETON, N.J., July 8 DOR BioPharma, Inc. ... a late-stage biopharmaceutical company, announced today that it ... Lipid Polymer Micelle (LPM(TM)) technology for the improved ... EP 1460992, entitled "Stabilized Reverse Micelle Compositions and ...
... of Wisconsin-Madison biomedical engineer and colleagues have developed a ... could spare some women with increased breast cancer risk ... biopsy of a questionable lump or lesion. The ... classifying a lesion as malignant or benign. ...
... advanced energy research , , MONTREAL, July 7 ... technology company, today announced that it will jointly form ... Edmonton and the Alberta Energy Research Institute (AERI). , ... demonstration of novel catalytic conversion processes to produce advanced ...
Cached Biology Technology:DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology 2DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology 3DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology 4DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology 5New MRI technique could mean fewer breast biopsies in high-risk women 2Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 2Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 3
(Date:12/22/2014)... Dec. 22, 2014 Research and Markets ... the addition of the "The Global ... their offering. ... an overview of the global digital media ... control and monitor piracy by securely and ...
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ... its team and bring LaunchKey to market in 2015. ...
(Date:12/17/2014)... , Dec. 16, 2014 Research and ... the addition of the "Global Chemical Sensor ... http://photos.prnewswire.com/prnh/20130307/600769 ... the increasing demand for medical sensors in biomedical ... data for quick and correct diagnosis during surgical ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... Service Weekly PressPac with news from ACS, 34 peer-reviewed journals ... journal or the American Chemical Society as the source for ... Clothing to crow about: Chicken feather suits and dresses, ... up in warm, cozy sweats made of chicken feathers or ...
... technologies that make it easier to sequence the human ... Center have identified a series of genes that become ... These recurrent gene fusions are thought to be the ... The gene fusions discovered could potentially serve as a ...
... Researchers at Mayo Clinic have discovered the first ... In the Jan. 11 online edition of Nature ... genome-wide association study of patients with Alzheimer,s disease. The ... a variant in the PCDH11X gene, found on the ...
Cached Biology News:American Chemical Society's Weekly PressPac -- Jan. 7, 2009 2American Chemical Society's Weekly PressPac -- Jan. 7, 2009 3American Chemical Society's Weekly PressPac -- Jan. 7, 2009 4American Chemical Society's Weekly PressPac -- Jan. 7, 2009 5American Chemical Society's Weekly PressPac -- Jan. 7, 2009 6American Chemical Society's Weekly PressPac -- Jan. 7, 2009 7American Chemical Society's Weekly PressPac -- Jan. 7, 2009 8American Chemical Society's Weekly PressPac -- Jan. 7, 2009 9U-M researchers discover new genes that fuse in cancer 2Mayo: Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's 2Mayo: Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's 3
... nmol (individual) with sequence siTrio siRNA ... to your target gene of interestis our most ... more than 75% knockdown of your target gene ... for transfection and confirmation of optimal transfection with ...
The Bio-Plex Manager version 3.0 to 4.0 workstation software upgrade kit is used to upgrade existing Bio-Plex Manager version 3.0 software to version 4.0 security edition software....
... rigid macroporous hydrophilic media. The rigid polymer ... pressures, while the macroporous beads enhance access ... reduces nonspecific binding. Macro-Prep High Q support ... very high flow rates and resolution. It ...
... --- a cocktail of 3 siRNAs specifically ... our most popular product. The siTrio reagent ... of your target gene when used under ... and confirmation of optimal transfection with one ...
Biology Products: