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Biocept, Inc. Announces New CFO
Date:7/15/2011

s of circulating tumor cells (CTCs). Biocept's mission is to enhance the lives of cancer patients through the development of innovative diagnostic products and services. Biocept utilizes innovative, proprietary technologies to deliver clinically relevant and actionable information to physicians that enable better patient care. This includes clinical assessments of CTCs, both prognostic and predictive, which may provide physicians with information highly relevant for the treatment of their patients with cancer.

About OncoCEE™

The OncoCEE™ platform, developed by Biocept, has demonstrated that it can consistently and accurately capture extremely rare cells, like CTCs, which may be present in only 1 of every 50-100 billion blood cells.  Biocept obtains patient samples via a simple blood draw, or "liquid biopsy", instead of relying on traditional biopsy methods or surgical procedures.  Biocept differentiates its "liquid biopsy" CTC analysis by combining enhanced prognostic (CTC enumeration) and predictive (e.g., HER2 status) biomarker analyses, information not currently available through commercial laboratories using existing technologies for CTC testing.  Other methods to capture, detect and enumerate CTCs rely only on the expression of epithelial cell adhesion molecule (EpCAM) and cytokeratins, and do not include molecular biomarker analysis.  This approach may exclude CTCs that have undergone intrinsic modifications of their phenotype, such as the epithelial-to-mesenchymal transition (EMT).  EMT may represent a possible explanation for many patients who, despite having aggressive disease, are found negative for the presence of CTCs. OncoCEE™ has the potential to capture not only epithelial (i.e., EpCAM positive) but also mesenchymal-like CTCs.  Additionally, the OncoCEE™ platform enables evaluation of predictive biomarkers by techniques like immunocytochemistry, fluorescence in situ hybridizati
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