Navigation Links
BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
Date:1/12/2009

EXTON, Pa., Jan. 12 /PRNewswire/ -- BioTrends Research Group, Inc. released TreatmentTrends(TM): US Nephrology, a syndicated report based on online survey results from 305 Nephrologists in the US.

The renal anemia market continues to show signs of stabilization. While the percent of patients with Chronic Kidney Disease not on dialysis (CKD) on ESAs declined significantly compared to the same period last year, only a small percent of Nephrologists reported making any changes in the past three months in their use of ESAs. The most noteworthy upcoming changes in this market may come from the proposed bundling structure under which Nephrologists project shifts to subcutaneous dosing, less aggressive treatment of EPO hypo-responders, and increased focus on patients' iron status. The commercialization of new ESAs could also alter market dynamics in which Amgen's Epogen currently leads the dialysis market and Ortho Biotech's Procrit and Amgen's Aranesp virtually split the CKD market. Even though the perceived need for new ESA therapies is relatively low, ESAs with extended dosing intervals are desired in CKD and ESAs with less hemoglobin variability are desired in dialysis. And among those aware of Affymax's Hematide, currently in development, interest is high.

The IV iron market, on the other hand, is likely to see more changes in the near-term with the potential approval of AMAG's Feraheme (ferumoxytol), which could be commercially available in the first half of 2009. Although awareness of this product remains relatively low, significant increases in representative activity were reported this quarter. In the CKD market, oral iron continues to be the first line treatment of choice over IV iron, and rationale for this tends to center around convenience, a potential advantage for Feraheme due to its perceived dosing and administration benefits. Contrary to the CKD market, in dialysis, the majority of patients are on IV iron and Nephrologists report preferring a preventative strategy employing maintenance dosing to manage iron deficiency versus the reactive strategy in line with repletion dosing that is most common in CKD. Despite these differences, Nephrologists report optimistic projections for Feraheme in both the dialysis and CKD markets, drawing share from American Regent's/Fresenius Medical Care's Venofer and Watson's Ferrlecit.

Many potential new products are also on the horizon in the phosphate binder market, albeit longer term. New products will likely be welcome additions as Nephrologists report that over one-third of their patients are not well-controlled on currently available binders. A binder that could be given with less frequency (as opposed to every meal) would likely have a considerable impact on market dynamics as the largest group of Nephrologists report patient non-compliance due to the frequency with which current binders have to be taken as the main reason phosphorus is difficult to control in dialysis patients. A more near-term shift in market dynamics will likely come from the recent introduction of generic calcium acetate from Roxane Laboratories, as very few Nephrologists oppose the substitution of a generic for Fresenius Medical Care's PhosLo. Another recent market shift came with the introduction of Genzyme's Renvela in Q108. Although the growth of Renvela seems to be fueled by cannibalization of Renagel, Nephrologists expect increases in overall sevelamer share in both dialysis and CKD, as well as increases in Shire's Fosrenol, while continued shifts are expected away from calcium based binders.

The proposed bundling structure is also expected to greatly impact the Vitamin D market, with over 50% of Nephrologists reporting they would shift away from IV Vitamin D to oral Vitamin D as their first line choice in hemodialysis patients. Another change in this market may be in the use of Nutritional Vitamin D, with over one third of Nephrologists expecting to increase their use of Nutritional Vitamin D in dialysis patients and close to half expecting to increase their use in CKD patients in the next six months. Despite these expected changes, the market has been relatively stable from a market share perspective as Abbott's Zemplar continues to hold its position as the leader in the dialysis market and calcitriol continues to hold this position in CKD. Use of Amgen's Sensipar has also been relatively stable, although Nephrologists continue to report an expected increase in use across both dialysis and CKD patients.

About BioTrends Research Group, Inc.

BioTrends Research Group, Inc. (www.bio-trends.com) provides syndicated and custom market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please contact us at (610) 363-3872 or www.bio-trends.com.

All company, brand, or product names contained in this document may be trademarks of their respective holders.

    Contact:
    Jennifer Robinson
    BioTrends Research Group, Inc.
    610-363-3872


'/>"/>
SOURCE BioTrends Research Group, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. European Nephrologists Share Insights on the Management of Renal Anemia and Hyperphosphatemia in Latest BioTrends Report
2. BioTrends Releases TreatmentTrends(TM): Nephrology and Renal Dietitians, Two Syndicated Reports Providing Continuing Insight into the Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
3. BioTrends Research Group, Inc. Recognized as One of Philadelphias Fastest Growing Privately Held Companies
4. New Study by BioTrends Highlights Anemia Practice Patterns According to Anemia Managers in Both Dialysis Units and CKD Clinics/Offices
5. BioTrends Releases Quarterly TreatmentTrends(TM): Nephrology Report Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
6. New Study by BioTrends Highlights Practice Management Shifts Among European Nephrologists
7. BioTrends Releases Two Publications - TreatmentTrends(TM): Nephrologists and TreatmentTrends(TM): Renal Dietitians - Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
8. BioTrends Releases Fourth Annual Nephrology TreatmentTrends Publication Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
9. CEL-SCI Corporation Releases Letter to Shareholders
10. The American Ceramic Society releases new ACerS-NIST phase equilibria diagrams CD-ROM database
11. The International Society for Stem Cell Research Releases New Guidelines to Shape Future of Stem Cell Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... December 08, 2016 , ... ... World Technology Awards. uBiome is one of just six company finalists in the ... In addition to uBiome, companies nominated as finalists in this year’s awards include ...
(Date:12/8/2016)... N.J. , Dec. 8, 2016 Soligenix, ... biopharmaceutical company focused on developing and commercializing products to ... need, announced today that it will be hosting an ... am ET on the origins of innate defense regulators ... a review of oral mucositis and the recently announced ...
(Date:12/8/2016)... Eutilex Co. Ltd. today announced that it ... A financing. This financing round included participation from DS ... Bio Angel. This new funding brings the total capital ... since its founding in 2015. The ... commercialization of its immuno-oncology programs, expand its R&D capabilities ...
(Date:12/7/2016)... San Diego (PRWEB) , ... December 07, 2016 ... ... safety data from its phase I/II dose escalation and expansion clinical trial for ... 2016 in Vienna, Austria. The purpose of the trial was to determine the ...
Breaking Biology Technology:
(Date:11/22/2016)... Nov. 22, 2016   MedNet Solutions , an ... spectrum of clinical research, is pleased to announce that ... Healthcare and Life Sciences Awards as "Most Outstanding ... an unprecedented year of recognition and growth for MedNet, ... 15 years. iMedNet ™ , ...
(Date:11/16/2016)... Nov. 16, 2016 Sensory Inc ., ... security for consumer electronics, and VeriTran , ... retail industry, today announced a global partnership that ... to authenticate users of mobile banking and mobile ... software which requires no specialized biometric scanners, ...
(Date:6/27/2016)... Research and Markets has announced the addition ... to their offering. The report ... to grow at a CAGR of 12.28% during the period 2016-2020. ... in-depth market analysis with inputs from industry experts. The report covers ... The report also includes a discussion of the key vendors operating ...
Breaking Biology News(10 mins):