Navigation Links
BioTech Holdings Announces First Clinical Use of Microbiome Optimized Autologous Stem Cells
Date:7/7/2017

SAN DIEGO, July 7, 2017 /PRNewswire/ -- BioTech Holdings announced today clinical safety data on 3 patients suffering from critical limb ischemia treated with the Company's Procell microbiome-optimized personalized stem cell product. 

In the investigator initiated pilot study, patients with diabetes associated circulation deficit in the legs (critical limb ischemia), who failed previous treatments were administered their own bone marrow derived stem cells that were treated with the Company's proprietary microbiome-derived compounds. 

No treatment associated adverse reactions were observed and patients were followed-up for 3 months.  Furthermore, 2 of the 3 patients had documented improvement in leg circulation and healing of previously unhealing ulcers.

"It is well known that the microbiome controls many aspects of human health and disease ranging from obesity, to autoimmunity, to even neurological function," said Thomas E Ichim, Ph.D, President and CEO of Biotech Holdings. "We are fortunate to have filed intellectual property on application of probiotics and microbiome manipulation to stem cells more than a year ago1.  The current study supports our forward movement of our ProCell product to formal clinical trials."

The Company's product, Procell, comprises of bone marrow stem cells from the same patient, that are treated with factors generated by the microbiome of healthy patients. The key ingredient that the company has identified as secreted by the microbiome which augments stem cell activity is already approved by the FDA for other indications. Accordingly, the company believes it is eligible for accelerated FDA registration pathways, including the 505b2 pathway.

The Company intends to develop the indication of critical limb ischemia as its first condition. Patients with this conditions have a major amputation rate as high as 40% at 6 months and a mortality rate of 20% to 25% in the first year after presentation. Critical limb ischemia represents a market of approximately 10 billion dollar per year2.

Contacts

Thomas E Ichim, Ph.D
President and Chief Executive Officer
BioTech Holdings
9255 Towne Centre Drive, #450
San Diego, CA 92121
167146@email4pr.com 
858 353 4303
Twitter: @biotechholdings

1 http://www.prnewswire.com/news-releases/biotech-holdings-announces-positive-preclinical-results-on-procell-probiotic-cell-therapy-for-critical-limb-ischemia-300278136.html

2 http://www.pluristem.com/wp-content/uploads/2016/04/Pluristem-January-2017.pdf

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/biotech-holdings-announces-first-clinical-use-of-microbiome-optimized-autologous-stem-cells-300484814.html


'/>"/>
SOURCE Biotech Holdings
Copyright©2017 PR Newswire.
All rights reserved


Related biology technology :

1. Founders of Philadelphia Biotech Enterin Inc. Discover Link Between Upper GI Tract Infections and Parkinsons Disease
2. Kibow Biotech Inc. (Buzz of Bio Winner, 2014) Receives US Patent for Gout/Hyperuricemia Product Formulation Based on Modulation of the Gut Microbiome With Probiotics and Prebiotics
3. Sentien Biotechnologies, Inc. Announces Open Enrollment in Phase 1/2 Trial of SBI-101 for Patients with Acute Kidney Injury
4. Greater Gainesville Region Advances as Florida’s Leading Location for Biotech Incubation and Technology Transfer
5. Pathway for Veterans into the Biotech Industry
6. UConn Innovation Fund Provides First Round Funding to Three Biotech Startups
7. Biotech Stocks Under Scanner -- Biostage, Keryx Biopharma, Kite Pharma, and ZIOPHARM Oncology
8. Research Reports Initiation on Biotech Stocks -- Tesaro, Alnylam Pharma, Corbus Pharma, and Inovio Pharma
9. Superior Controls and Banks Integration Group Merge, Creating Industry-Leading Biotech System Integration Company
10. iPath Media and DoyleCreek Strategic Communications Join Forces to Offer New Marketing Services to Pharmaceutical and Biotech Companies
11. Maxwell Biotech Venture Funds Portfolio Company Hepatera LLC Announces Completion of Recruitment for Phase 2b Clinical Trials of Myrcludex B in Chronic Hepatitis Delta
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/26/2017)... ... July 26, 2017 , ... ... for the improvement of crop productivity and economics for the food, feed and ... scope of the agreement includes the research and development of microbiome-based seed treatments ...
(Date:7/25/2017)... , ... July 25, 2017 ... ... to welcome Chuck Heinz as Executive Director of Strategic Planning. His extensive ... Benchworks team. , Chuck’s professional experience encompasses marketing and differentiation consulting, business ...
(Date:7/24/2017)... 2017 Intralytix, Inc. announced that it received ... French family group. This investment marks the beginning of ... commercialize bacteriophage-based products, for various benefits in human health ... As a global key ... markets innovative solutions for baking, food taste & pleasure, ...
(Date:7/20/2017)... ... July 20, 2017 , ... The Arnold and ... Thomson Professor of Electrical Engineering and Computer Science at the Massachusetts Institute of ... the award recognizes an individual who has made and is continuing to make ...
Breaking Biology Technology:
(Date:5/16/2017)... , May 16, 2017   Bridge Patient ... organizations, and MD EMR Systems , an ... partner for GE, have established a partnership to ... product and the GE Centricity™ products, including Centricity ... These new integrations will allow ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... Annual Report on Form 10-K on Thursday April 13, 2017 with ... ... Relations section of the Company,s website at http://www.nxt-id.com  under "SEC ... . 2016 Year Highlights: Acquisition ...
(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
Breaking Biology News(10 mins):