Navigation Links
BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device
Date:6/17/2009

LAVAL, QC, June 17 /PRNewswire-FirstCall/ - BioSyntech, Inc. (TSX: BSY), a biotechnology company developing biotherapeutic thermogels for regenerative medicine, today announced statistically significant results from an analysis of patients who completed their 12 month follow-up in the BST-CarGel(R) randomized clinical trial. Specifically, statistically significant evidence of improved repair tissue quality due to BST-CarGel treatment was found during analyses of tissues biopsied from the knees of 22 patients. The ongoing multicenter pivotal trial is evaluating the ability of BST-CarGel to repair cartilage lesions in the knee when applied to a microfractured lesion compared to microfracture alone (control) in 80 patients. Final results on all 80 patients are expected in the first half of 2010.

"We are excited by these positive results, which will be highly supportive in our ongoing discussions with potential orthopedic partners. Although we have not yet completed all facets of this Interim Analysis, we felt obligated to disclose these first histology results as biopsy data is considered the gold standard for assessment of cartilage repair," said Mr. Michel Lagueux, Chairman of the Board.

Using histological methods (i.e. analyses by microscope) to process and analyze the biopsied tissues from 13 BST-CarGel patients and 9 microfracture patients, and using third parties to perform the statistical analysis, statistically significant improvements were identified for critical tissue characteristics following BST-CarGel treatment compared to microfracture alone. In particular, after applying the International Cartilage Repair Society's (ICRS) histological scoring systems I and II to the biopsies in a blinded manner, several parameters were found to be statistically significant between treatment groups at p(less than)0.05. First, the Overall ICRS II score was significantly better for the BST-CarGel group than for the microfracture group (p=0.045), with
'/>"/>

SOURCE BioSyntech, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. BioSyntech Achieves Enrolment Goal for Pivotal Trial of BST-CarGel(R), its Cartilage Repair Device
2. BioSyntech to conclude enrolment for pivotal BST-CarGel(R) trial in February 2009
3. Neurim Pharmaceuticals Reports Long Term Efficacy and Safety for Circadin(R) for Insomnia in Elderly Patients
4. Repligen Reports Fourth Quarter and Fiscal Year 2009 Financial Results
5. Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus
6. Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients
7. PeriCor Therapeutics Reports Positive Preclinical Results of GP531 at the European Heart Failure Congress in Nice
8. Mersana Reports Preliminary Phase 1 Results of XMT-1001 in Patients with Advanced Solid Tumors
9. Valeant Pharmaceuticals Reports Encouraging Final Results With Taribavirin Phase IIb Study
10. Biostar Pharmaceuticals, Inc. Reports Continued Revenues and Earnings Growth in First Quarter of 2009
11. Neptune Technologies Reports Fiscal 2009 Results - Record revenue and profitability growth in nutraceutical business
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... 2015 Psyche Systems Corporation and Luminate Health ... first-of-its-kind platform that helps labs comply with new federal ... the way patients engage with these results, and improves ... provides a HIPAA-compliant digital platform that gives labs an ... their lab results, and uniquely connects labs, physicians, and ...
(Date:5/5/2015)... Muncie, IN (PRWEB) May 05, 2015 ... that the state of Indiana, led by Indiana Gov. ... Aviation Day. The AMA Foundation will host a Family ... in celebration. All proceeds will benefit the Wounded Warrior ... by the Academy of Model Aeronautics—the country’s foremost organization ...
(Date:5/5/2015)... LOS ANGELES , May 5, 2015 ... and pioneer in providing on-demand access to scientific, technical ... purchasing agreement with the Association of Southeastern Research ... of 38 research libraries located across 11 southeastern states. ... developing innovative and collaborative programs to address the continually ...
(Date:5/5/2015)...  A group of biotechnology executives and medical doctors ... a non-profit organization dedicated to providing education, research and ... of consciousness.  ... Coma is ... voluntary actions can be initiated by the patient, and ...
Breaking Biology Technology:Psyche Systems Corporation Forms Strategic Alliance with Luminate Health to Provide First-of-its-kind Patient Access Solution 2Psyche Systems Corporation Forms Strategic Alliance with Luminate Health to Provide First-of-its-kind Patient Access Solution 3State of Indiana proclaims August 15 as Model Aviation Day 2Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 2Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 3Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 2Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 3Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 5
... 9 Soligenix, Inc. (Soligenix or the Company), (OTC ... that Robert J. Rubin, MD, has been appointed to ... a distinguished career in the healthcare industry and government. ... of the national health policy and management consulting firm ...
... ... Caskey and Saul Tendler to its Scientific Advisory Board , ... Westlake Village, Calif. (PRWEB) October 9, 2009 -- Nanogea, a ... to announce today that Dr. C. Thomas Caskey and Dr. Saul Tendler have joined ...
... ... program and is opening the call for entries. Established in 2003, this prestigious awards ... that manifestly improve some facet of the R&D/drug development/clinical trial process. , ... Needham, MA (PRWEB) October 8, ...
Cached Biology Technology:Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 2Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 3Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 4Nanogea Announces New Scientific Advisory Board Members 2Nanogea Announces New Scientific Advisory Board Members 3The 2010 Bio-IT World Best Practices Call for Entries has been Released -- Highlight your Company's Excellence in Innovation 2The 2010 Bio-IT World Best Practices Call for Entries has been Released -- Highlight your Company's Excellence in Innovation 3
(Date:3/30/2015)... Mar. 26, 2015 Research and Markets ... "Global Gesture Recognition Market in Automotive Sector 2014-2018" ... forecast the Global Gesture Recognition market in Automotive Sector ... period 2013-2018. Gesture recognition is the ability ... gestures of an individual. Gesture recognition technology can be ...
(Date:3/24/2015)... 24, 2015 Research and Markets ( ... "Global Iris Recognition Market 2015-2019" report to their ... Recognition market to grow at a CAGR of 23.5 ... covers the present scenario and the growth prospects of ... To calculate the market size, the report considers the ...
(Date:3/24/2015)... --  NexID Biometrics LLC, whose spoof-mitigation technology boosts ... the beginning of shipments of version 2.0 of its ... based in Potsdam, N.Y. , is ... began here today at the Walter E. Washington Convention ... SDK boosts the accuracy rate range to 96.5 to ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2
... medical information beyond what current newborn screening already provides? ... funded by the Eunice Kennedy Shriver National Institute of ... Human Genome Research Institute (NHGRI), both parts of the ... four grantees have been made in fiscal year 2013 ...
... a polyphenolic compound, is synthesized in several plants ... anti-inflammatory and anti-carcinogenic properties. Resveratrol exhibits neuroprotective effects ... ischemia, Huntington,s disease, Parkinson,s disease and Alzheimer,s disease. ... the effect of resveratrol in vascular dementia. Dr ...
... September 4, 2013 A study published today ... tool to accurately analyze extremely rare mitochondrial DNA (mtDNA) ... as well as aging. This approach, which relies on ... researchers explore mtDNA deletions as potential disease biomarkers. ...
Cached Biology News:NIH program explores the use of genomic sequencing in newborn healthcare 2NIH program explores the use of genomic sequencing in newborn healthcare 3NIH program explores the use of genomic sequencing in newborn healthcare 4Extremely rare mitochondrial DNA deletions associated with aging can be accurately detected with Droplet Digital PCR 2Extremely rare mitochondrial DNA deletions associated with aging can be accurately detected with Droplet Digital PCR 3
... Kit (E-22013) provides,researchers with a sensitive ... in solution. This fluorescence-based assay can ... (Figure 1). The assay,measures lysozyme activity ... labeled to such a degree that ...
... (Cap Analog) is used for the synthesis ... vitro transcription reactions. Substitution of cap analog ... in an in vitro transcription reaction results ... into a large fraction of the transcripts. ...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. It can incubate up to ...
iEMS Thermal Microplate Holder...
Biology Products: