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BioSpecifics Technologies Corp. Announces Data Presentations at Upcoming XVI Annual Federation of the European Societies for Surgery of the Hand Meeting
Date:5/18/2011

triple helical region of collagen under physiological conditions. The specific substrate collagen comprises approximately one-third of the total protein in mammalian organisms, and it is the main constituent of skin, tendon and cartilage, as well as the organic component of teeth and bone. The body relies on endogenous collagenase production to remove dead tissue, and collagenase production is an essential biological mechanism that regulates matrix remodeling and the normal turnover of tissue. The Clostridial collagenase produced by BioSpecifics has a broad specificity towards all types of collagen and is acknowledged as much more efficient than mammalian collagenases. Clostridial collagenase cleaves the collagen molecule at multiple sites along the triple helix, whereas the mammalian collagenase is only able to cleave the molecule at a single site along the triple helix. Because collagenase does not damage the cell membrane, it is widely used for cell dispersion for tissue disassociation and cell culture.

There are a number of medical conditions that can result from an excess accumulation of collagen. Collagenase offers a minimally invasive treatment option for patients and can be administered in an office setting. It holds considerable therapeutic potential to change the way patients are treated for a variety of diseases and indications.

About F.E.S.S.H.

The Federation of European Societies for Surgery of the Hand (F.E.S.S.H.) is an organization which represents national hand surgery societies in Europe. Its object is to improve the standard of hand surgery throughout Europe. It seeks to develop surgical resources by advising European authorities of the requirements and appropriate quality of hand care.

The purpose of F.E.S.S.H. is to rationalize and unify the training and educational structure for qualification of European hand surgery specialists. The standard would be the amount and level of knowledge approved for the
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