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BioRealm to Develop Universal Genetic Screening Tool for Tobacco Addiction and Treatment
Date:6/20/2012

Los Angeles, CA (PRWEB) June 20, 2012

BioRealm, LLC announced today that it has been awarded a Small Business Innovative Research contract by the U.S. National Institute on Drug Abuse (NIDA) to develop a universal genetic screening tool for tobacco addiction and treatment approaches. BioRealm’s “Smokescreen” product will integrate recent advances in tobacco addiction research and allow researchers to study thousands of an individual’s genetic variants related to tobacco dependence and treatment response.

According to the Centers for Disease Control and Prevention (CDC), smoking is the leading cause of preventable disease in the U.S., resulting in $96 billion in annual health care costs. Despite the availability of numerous smoking cessation products and treatments, effectiveness varies greatly and people often relapse. Studies have shown that genetic variation plays a significant role in nicotine dependence, including the ability to quit smoking and response to nicotine replacement therapy and medication. However, the genetics of tobacco addiction are not yet fully understood.

Addiction researchers have so far been limited by the small number of participants in clinical trials, and the lack of a validated genetic screening tool and centralized database for storing results. “The Smokescreen aims to solve these problems by featuring a uniform set of genetic variants, with genotyping results automatically stored and accessible via a secure cloud-based application”, stated Christopher Edlund, Bioinformatics Principal at BioRealm. “The ability to seamlessly share and compare data across multiple studies will enable researchers and clinicians to more effectively investigate tobacco addiction”.

Scientists at BioRealm envision the Smokescreen to be the standard genetic test used by clinical trials for smoking cessation. “The Smokescreen will be an invaluable resource for developing personalized smoking cessation t
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