Navigation Links
BioRealm Receives $1 million NIDA Award to Launch the Smokescreen® Genotyping Array for Research on Tobacco Dependence and Treatment Approaches

Monument, CO (PRWEB) August 01, 2013

BioRealm, LLC announced today it was awarded a $1 million Small Business Innovative Research (SBIR) Phase II contract from the National Institute on Drug Abuse (NIDA) to develop and launch the Smokescreen® genotyping array for research on tobacco dependence and treatment approaches. The array uses Affymetrix’ Axiom® genotyping technology to screen over 600,000 genetic variants to support research related to nicotine addiction, smoking cessation therapies, and consequences of tobacco use.

Smoking continues to be a leading preventable cause of disease, disability and death in the United States and worldwide. According to a recent report from the Centers for Disease Control and Prevention, smoking was estimated to be responsible for $96 billion in healthcare costs and an additional $97 billion in lost productivity in the United States annually. Due to the highly addictive properties of nicotine, people attempting to quit smoking often fail. Genetics is known to play a role in how strongly tobacco users become addicted and how they respond to different cessation therapies.

The Smokescreen product will be a targeted genotyping and software solution for scientists studying the genetics of nicotine addiction and smoking behavior, including those conducting clinical trials of smoking cessation therapies. The array will have excellent coverage of genomic regions associated with addiction, as well as biological pathways related to the metabolism of nicotine and the brain’s reward system. “Large-scale, disease-specific genotyping arrays have had a lot of success following up on prior research and discovering new risk loci”, stated Christopher Edlund, Bioinformatics Principal at BioRealm. "Tobacco addiction scientists will now have a unified genotyping array designed specifically for their research domain."

According to BioRealm, customers of Smokescreen will access their study data via a secure software application, built using the team’s statistical computing and genetics expertise. The software will feature automated quality control, data analysis pipelines, and the ability for researchers from different institutions to combine their data for powerful analyses.

During the two-year project, BioRealm will collaborate with top addiction researchers to develop a roadmap for future clinical products. "An important part of this project will be building a framework for biomarker development, which may classify smokers and suggest smoking cessation therapies based on individual characteristics, including genetics," said Dr. James Baurley, Co-founder of BioRealm. "Our team will be developing state-of-the-art statistical methods that combine all available data to build predictive models. This includes biological information, existing study data, and Smokescreen data as it becomes available."

BioRealm is currently enrolling early-access users of the Smokescreen platform. Manufacturing of Smokescreen genotyping arrays is expected to begin in the fourth quarter of 2013. Additional information related to the Smokescreen product and early access could be found at

About BioRealm:

Founded in 2006, BioRealm develops solutions for genetic research and the biomedical industry.

This project has been funded in whole or in part with Federal funds from the National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN271201300004C.

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. BioRealm to Develop Universal Genetic Screening Tool for Tobacco Addiction and Treatment
2. UCSB professor receives award for graphene electronics research
3. Watsons Generic Yaz(R) Receives FDA Approval
4. Quanterix Receives Funding From the Department of Homeland Security to Develop Test for Botulinum Toxin
5. Life Technologies Ion Personal Genome Machine Receives San Diegos CONNECT Most Innovative New Product Award
6. MacroGenics Receives Milestone Payment as Part of Its Global DART™ Alliance with Boehringer Ingelheim
7. Intimate Bridge 2 Conception, Inc. Receives $4.3M
8. Pacific Meso Center Receives Generous Donation to First Free-Standing Mesothelioma Research Laboratory in Los Angeles
9. BioNeutral Group Receives $400,000 in Equity Financing
10. Amsterdam Molecular Therapeutics Receives US Orphan Designation for Hemophilia B Gene Therapy
11. Arcion Receives Notice of Allowance for US Patent for Novel Topical Lidocaine Formulation for Pain
Post Your Comments:
(Date:6/24/2016)... , ... June 24, 2016 , ... While the majority ... as the Cary 5000 and the 6000i models are higher end machines that use ... height of the spectrophotometer’s light beam from the bottom of the cuvette holder. ...
(Date:6/23/2016)... , June 23, 2016 /PRNewswire/ - FACIT has ... Ontario biotechnology company, Propellon Therapeutics Inc. ... and commercialization of a portfolio of first-in-class WDR5 ... targets such as WDR5 represent an exciting class ... in precision medicine for cancer patients. Substantial advances ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
Breaking Biology Technology:
(Date:6/9/2016)...  Perkotek an innovation leader in attendance control systems is proud to announce the ... employers to make sure the right employees are actually signing in, and to even ... ... ... ...
(Date:6/2/2016)... 2, 2016   The Weather Company , an IBM ... an industry-first capability in which consumers will be able to ... ask questions via voice or text and receive relevant information ... Marketers have long sought an advertising solution that ... be personal, relevant and valuable; and can scale across millions ...
(Date:5/16/2016)... May 16, 2016   EyeLock LLC , a ... the opening of an IoT Center of Excellence in ... expand the development of embedded iris biometric applications. ... of convenience and security with unmatched biometric accuracy, making ... aside from DNA. EyeLock,s platform uses video technology to ...
Breaking Biology News(10 mins):