Navigation Links
BioRealm Receives $1 million NIDA Award to Launch the Smokescreen® Genotyping Array for Research on Tobacco Dependence and Treatment Approaches
Date:8/1/2013

Monument, CO (PRWEB) August 01, 2013

BioRealm, LLC announced today it was awarded a $1 million Small Business Innovative Research (SBIR) Phase II contract from the National Institute on Drug Abuse (NIDA) to develop and launch the Smokescreen® genotyping array for research on tobacco dependence and treatment approaches. The array uses Affymetrix’ Axiom® genotyping technology to screen over 600,000 genetic variants to support research related to nicotine addiction, smoking cessation therapies, and consequences of tobacco use.

Smoking continues to be a leading preventable cause of disease, disability and death in the United States and worldwide. According to a recent report from the Centers for Disease Control and Prevention, smoking was estimated to be responsible for $96 billion in healthcare costs and an additional $97 billion in lost productivity in the United States annually. Due to the highly addictive properties of nicotine, people attempting to quit smoking often fail. Genetics is known to play a role in how strongly tobacco users become addicted and how they respond to different cessation therapies.

The Smokescreen product will be a targeted genotyping and software solution for scientists studying the genetics of nicotine addiction and smoking behavior, including those conducting clinical trials of smoking cessation therapies. The array will have excellent coverage of genomic regions associated with addiction, as well as biological pathways related to the metabolism of nicotine and the brain’s reward system. “Large-scale, disease-specific genotyping arrays have had a lot of success following up on prior research and discovering new risk loci”, stated Christopher Edlund, Bioinformatics Principal at BioRealm. "Tobacco addiction scientists will now have a unified genotyping array designed specifically for their research domain."

According to BioRealm, customers of Smokescreen will access their study data via a secure software application, built using the team’s statistical computing and genetics expertise. The software will feature automated quality control, data analysis pipelines, and the ability for researchers from different institutions to combine their data for powerful analyses.

During the two-year project, BioRealm will collaborate with top addiction researchers to develop a roadmap for future clinical products. "An important part of this project will be building a framework for biomarker development, which may classify smokers and suggest smoking cessation therapies based on individual characteristics, including genetics," said Dr. James Baurley, Co-founder of BioRealm. "Our team will be developing state-of-the-art statistical methods that combine all available data to build predictive models. This includes biological information, existing study data, and Smokescreen data as it becomes available."

BioRealm is currently enrolling early-access users of the Smokescreen platform. Manufacturing of Smokescreen genotyping arrays is expected to begin in the fourth quarter of 2013. Additional information related to the Smokescreen product and early access could be found at https://biorealmresearch.com/smokescreen.

About BioRealm:

Founded in 2006, BioRealm develops solutions for genetic research and the biomedical industry.

This project has been funded in whole or in part with Federal funds from the National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN271201300004C.

Read the full story at http://www.prweb.com/releases/2013/8/prweb10985208.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. BioRealm to Develop Universal Genetic Screening Tool for Tobacco Addiction and Treatment
2. UCSB professor receives award for graphene electronics research
3. Watsons Generic Yaz(R) Receives FDA Approval
4. Quanterix Receives Funding From the Department of Homeland Security to Develop Test for Botulinum Toxin
5. Life Technologies Ion Personal Genome Machine Receives San Diegos CONNECT Most Innovative New Product Award
6. MacroGenics Receives Milestone Payment as Part of Its Global DART™ Alliance with Boehringer Ingelheim
7. Intimate Bridge 2 Conception, Inc. Receives $4.3M
8. Pacific Meso Center Receives Generous Donation to First Free-Standing Mesothelioma Research Laboratory in Los Angeles
9. BioNeutral Group Receives $400,000 in Equity Financing
10. Amsterdam Molecular Therapeutics Receives US Orphan Designation for Hemophilia B Gene Therapy
11. Arcion Receives Notice of Allowance for US Patent for Novel Topical Lidocaine Formulation for Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... The global biotechnology services outsourcing market ... 2025, according to a new report by Grand ... of the function of outsourcing certain clinical and ... services outsourced, clinical trial management and contract manufacturing ... was the first pharmaceutical company to outsource its ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... device-to-computer interconnect using USB or PCI Express, announced the ZEM5310 USB 3.0 FPGA ... FPGA into a compact business-card sized form factor suitable for prototyping, testing, and ...
(Date:1/18/2017)... Jan. 18, 2017   Parent Project Muscular Dystrophy ... end Duchenne muscular dystrophy (Duchenne) , today announced ... Jersey Institute of Technology (NJIT) and Talem Technologies (Talem) ... robotic technology to assist people living with Duchenne. ... technology – an embedded computer, software, a force sensor ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... bio-focused Manufacturing Innovation Institutes (MII). U.S. Secretary of Commerce Penny Pritzker has announced ... and the Department of Defense has announced the award of a new Advanced ...
Breaking Biology Technology:
(Date:12/15/2016)... Calif. , Dec. 15, 2016   WaferGen ... publicly held genomics technology company, announced today that on ... Listing Qualifications Department of The Nasdaq Stock Market LLC ... closing bid price of WaferGen,s common stock had been ... Accordingly, WaferGen has regained compliance with Listing Rule 5550(a)(2) ...
(Date:12/15/2016)... , Dec. 15, 2016  There is much ... doors or starting the engine. Continental will demonstrate the ... Las Vegas . Through the combination of ... and Entry) and biometric elements, the international technology company ... vehicle personalization and authentication. "The integration of ...
(Date:12/8/2016)... 2016 Market Research Future published a half cooked research ... Biometric Security and Service Market is expected to grow over the ... Market Highlights: ... Mobile Biometric Security and Service Market ... need of authentication and security from unwanted cyber threats. The increasing ...
Breaking Biology News(10 mins):