Navigation Links
BioMarin and IGAN Biosciences to Collaborate on Development of an Enzyme Therapy to Treat IgA Nephropathy, a Rare and Life-Threatening Kidney Disease
Date:12/3/2007

NOVATO, Calif., Dec. 3 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq and SWX: BMRN) and IGAN Biosciences announced today that they have initiated a program to develop an IgA protease for treating IgA nephropathy. IgA proteases have been shown to cleave IgA complexes, the deposition of which causes IgA nephropathy, an orphan kidney disorder with few treatment alternatives. BioMarin has executed a research and option agreement with IGAN Biosciences for intellectual property covering IgA proteases for treating IgA nephropathy.

"IgA proteases have the potential to reverse or prevent progression of IgA Nephropathy," said Dr. Andrew Plaut, discoverer of IgA proteases, Professor of Medicine at Tufts University School of Medicine, and Chairman of IGAN Biosciences. "Current treatments are not very effective, and nothing on the horizon looks very promising. BioMarin has a strong track record of aggressively developing disease modifying therapeutics for rare disorders, and I am very pleased that they have made a commitment to further these important efforts."

"Dr. Plaut's laboratory has performed pioneering work in the field of IgA proteases," Emil Kakkis, M.D., Ph.D., Chief Medical Officer of BioMarin commented. "These proteases are exceptionally specific for IgA and show promise for treating the underlying pathophysiology of IgA nephropathy. In collaboration with IGAN and the Tufts-New England Medical Center, we look forward to testing these proteases in animal models of IgA nephropathy, and if successful, developing an efficacious therapeutic for the disorder."

"We are pleased to add this program to our growing product development pipeline. The IgA nephropathy indication aligns well with our development and commercial competencies as it is a protein therapeutic for treating a well- defined and relatively large orphan disorder treated by renal specialists," said Jean-Jacques Bienaime, Chief Executive Officer of BioMarin. "Well val
'/>"/>

SOURCE BioMarin Pharmaceutical Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. BioMarin Licenses Technology From Leading Cystic Fibrosis Research Laboratory at the University of California, San Francisco
2. BioMarin to Present at the BioCentury NewsMakers Conference
3. BioMarin to Present at the Rodman & Renshaw 9th Annual Healthcare Conference
4. YM BIOSCIENCES ANNOUNCES COMPLIANCE WITH AIM RULE 26
5. Selection of Development Candidate Triggers $0.5 Million Milestone Payment to Ardea Biosciences, Inc.
6. ImmuneRegen BioSciences Files 8-K that Highlights Enclosed Shareholder Letter Discussing Recent Achievements and Outlook
7. ONCOSCIENCE AG, THE EUROPEAN PARTNER OF YM BIOSCIENCES, ANNOUNCES COMPLETION OF PATIENT ENROLLMENT IN PHASE III BRAIN CANCER TRIAL OF NIMOTUZUMAB
8. Pressure BioSciences, Inc. Reports Second Quarter 2007 Financial Results and Provides Business Update
9. YM BIOSCIENCES, EUROPEAN PARTNER, ONCOSCIENCE AG, ANNOUNCES INITIATION OF ADVANCED NIMOTUZUMAB TRIALS IN ADULT GLIOMA AND PANCREATIC CANCER
10. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2007
11. Magellan Biosciences Names Steven E. Diamond, PhD, Chief Scientific Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... 2014 Research and Markets has ... Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, ... their offering. The global molecular biology ... and is expected to grow at a CAGR of ... enzymes, kits, & reagents find applications in a large ...
(Date:8/22/2014)... Canada (PRWEB) August 22, 2014 ... in model organisms can be accelerated by exome ... and manufacturing technologies, the custom SeqCap EZ Developer ... research. , Mr. Watson will additionally present how ... with commercially available human and mouse exome kits. ...
(Date:8/21/2014)... PA & Rockville, MD (PRWEB) August 21, 2014 ... (ITI) is making progress in its development of ... to Japanese red cedar pollen. Phase IC studies began ... a real solution to hay fever. , The Japanese ... over 35 million people in Japan. Mountain Cedar pollen ...
(Date:8/21/2014)... 2014 2014 Deep Research ... a professional and in-depth research report on ... basic Seaweed Fertilizer information, including Seaweed Fertilizer ... as well as industry overview. This research ... market as well as global industry analysis ...
Breaking Biology Technology:Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 2Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 3Efficient Identification of Protein-Coding Variants in a Model Organism Through Exome Sequencing, New Webinar Hosted by Xtalks 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 4Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3
... , BETHESDA, Md., Sept. 21 ... company developing novel, proprietary antibodies for the treatment of cancer, ... a phase 1 dose-escalation clinical study for BiTE antibody MT110, ... tumors. The interim data(1) were presented at the Multidisciplinary ...
... , , , ... 21 Volcano Corporation (Nasdaq: VOLC ), a leader ... and treatment of coronary and peripheral artery disease, announced today its ... Francisco, CA from September 21-25. Volcano programming for TCT includes a ...
... ST. PAUL, Minn., Sept. 21 Brennen Medical, LLC, ... device to Davol Inc., a subsidiary of C.R. Bard, Inc. ... of the hernia products business of Brennen Medical, LLC. This ... in soft tissue repair including hernia and abdominal wall reconstruction. , ...
Cached Biology Technology:Micromet Reports Interim Data from Phase 1 Study of BiTE Antibody MT110 for the Treatment of Solid Tumors 2Micromet Reports Interim Data from Phase 1 Study of BiTE Antibody MT110 for the Treatment of Solid Tumors 3Micromet Reports Interim Data from Phase 1 Study of BiTE Antibody MT110 for the Treatment of Solid Tumors 4Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics (TCT) Conference 2Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics (TCT) Conference 3Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics (TCT) Conference 4Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics (TCT) Conference 5Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics (TCT) Conference 6Brennen Medical Announces Sale of XenMatrix(R) 2
(Date:8/21/2014)... has successfully replicated one of the crucial steps in ... sunlight which could manufacture hydrogen as a fuel. , ... an exciting prospect to use them to create hydrogen, ... Hingorani, from the ARC Centre of Excellence for Translational ... Hydrogen offers potential as a zero-carbon replacement for petroleum ...
(Date:8/21/2014)... itself resulting in severe abdominal pain, vomiting and systemic ... are diagnosed with the disease resulting in 1000 deaths. ... to intravenous fluid and nutritional support. , Dr ... led the research, said "The major causes of pancreatitis ... alcohol intake combined with a high fat diet. In ...
(Date:8/20/2014)... a study of 158 pregnant teenagers in Rochester, NY, ... intentional consumption of ice, cornstarch, vacuum dust, baby powder ... Cornell study. , Moreover, such teens had significantly lower ... eat nonfood substances. , Pregnant teens, regardless of pica, ... lead to iron deficiency and anemia. Low iron in ...
Breaking Biology News(10 mins):Water and sunlight the formula for sustainable fuel 2Insulin offers new hope for the treatment of acute pancreatitis 2Pica in pregnant teens linked to low iron 2
... the behaviors of individual cells and the functions and ... the complex interactions of cell clusters have not been ... Emergent Behaviors of Integrated Cellular Systems (EBICS) Center to ... the University of Illinois at Urbana-Champaign, and the Georgia ...
... From how massive humpbacks glide through the sea with ease ... Harvard have excavated the equations behind a variety of complex ... Michael Brenner, working closely with a team of Harvard evolutionary ... most famous icon of evolution: the beaks of Darwin,s finches. ...
... industrialized countries have easy access to healthy food and nutritional ... because new research from Tel Aviv University suggests that magnesium, ... even more critical than previously thought for the neurons of ... MIT, the research started as a part of a post-doctoral ...
Cached Biology News:$25M NSF center established to investigate the creation of biological machines 2$25M NSF center established to investigate the creation of biological machines 3$25M NSF center established to investigate the creation of biological machines 4Simple math explains dramatic beak shape variation in Darwin's finches 2Simple math explains dramatic beak shape variation in Darwin's finches 3Remember magnesium if you want to remember 2
Mouse Activin RIB/ALK-4 MAb (Clone 207304)...
Normal human serum, single donor...
... SYBR Green, TaqMan, LNA spiked TaqMan, MethyLight, ... specific primers are designed by avoiding cross ... results. Primer efficiency is enhanced by avoiding ... the Mfold server. Beacon Designer can be ...
Agar, 5 lb. Bacteriological.Moisture: < 10%, ash: < 6.5%. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: