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BioMarin Announces Fourth Quarter and Full Year 2008 Financial Results
Date:2/18/2009

Operating expenses: Cost of sales (excludes amortization) 5,224 11,665 18,359 52,509 Research and development 24,015 25,733 78,600 93,291 Selling, general and administrative 23,891 28,730 77,539 106,566 Amortization of intangible assets 1,093 1,093 4,371 4,371 Total operating expenses 54,223 67,221 178,869 256,737 Income (loss) from operations (9,369) 32,056 (57,288) 39,756 Equity in the income (loss) of BioMarin/Genzyme LLC 9,366 (579) 30,525 (2,270) Interest income 7,383 3,231 25,932 16,388 Interest expense (4,080) (4,096) (14,243) (16,394) Impairment loss on investment -- (4,056) -- (4,056) Income (loss) before income taxes 3,300 26,556 (15,074) 33,424 Income Taxes 729 2,050 729 2,593 Net income (loss) $2,571 $24,506 $(15,803) $30,831 Net income (loss) per share, basic $0.03 $0.25 $(0.16) $0.31 Net income (loss) per share, diluted $0.03 $0.21 $(0.16) $0.29 Weighted average common shares outstanding, basic 96,931 99,777 95,878 98,975 Weighted average common shares outstanding, diluted 101,193 128,296 95,878 103,572

The following is the stock-based compensation expense included in the respective captions of the consolidated statements of operations above:

                                           Three Months
                                              Ended         Twelve Months
                                           December 31,  
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SOURCE BioMarin Pharmaceutical Inc.
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